Gene: F13a1

Basic information

Tag Content
Uniprot ID G3V811
Entrez ID 60327
Genbank protein ID EDL98278.1; EDL98279.1;
Genbank nucleotide ID NM_021698.2
Ensembl protein ID ENSRNOP00000021568
Ensembl nucleotide ID ENSRNOG00000015957
Gene name Coagulation factor XIII A chain
Gene symbol F13a1
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSDTPATTFG GRRAIPPNNS NAAEVDLPTE DLQGLVPRGV SLKDYLNVTA VHLFKERWDS 60
NKIDHHTDKY DNNKLIVRRG QTFYIQIDFN RPYDPRKDLF RVEYVIGRYP QENKGTYIPV 120
PVVTELQSGK WGAKVIMNED RSVRLSVQSS PECIVGKFRM YVAVWTPYGI LRTQRDPETD 180
TYILFNPWCE EDAVYLDDEK EREEYVLNDI GVIFHGDFND IKSRSWSYGQ FEDGILDACL 240
YVMDKAEMDL SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNVYAYGIPP SAWTGSVDIL 300
LEYRSSETPV RYGQCWVFAG VFNTFLRCLG IPARVITNYF SAHDNDANLQ MDIFLEEDGS 360
VSSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP QENSDGMYRC GPASVQAVKH 420
GHVCFQFDAP FVFAEVNSDL VYITAKKDGT HVVENVDATH IGKLIVTKEI GGDGMQDITD 480
TYKFQEGQEE ERLALETALM YGAKKTLNTE GVVKSRSDVD MNFDVENAVL GKDFRVTITF 540
QNNSSNLYTI LAYLSGNITF YTGVSKKEFK TESFEVTLDP LSLEKKEVLI RAGEYMSYLL 600
EQGLLHFFVT ARINETRVVL AKQKSIVLTI PKVTIKVRGT AMVGSDMVVT VEFTNPLKET 660
LKNVWLHLEG PGVMRPKRKM FREIRPNATV QWEEVCQPWV SGHRKLIASM TSDSLRHVYG 720
ELDLQIRRRP TV 732

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologF13A1F1PKX3Canis lupus familiarisPredictionMore>>
1:1 orthologF13A1102169238A0A452FF40Capra hircusPredictionMore>>
1:1 orthologF13A12162P00488CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologF13a174145Q8BH61Mus musculusPredictionMore>>
1:1 orthologF13A1462413H2QS92Pan troglodytesPredictionMore>>
1:1 orthologF13A1100153504K7GQL2Sus scrofaPredictionMore>>
1:1 orthologF13a160327G3V811Rattus norvegicusPredictionMore>>
1:1 orthologf13a1bF1R1R7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0046872 metal ion binding
GO:0003810 protein-glutamine gamma-glutamyltransferase activity
GO:0072378 blood coagulation, fibrin clot formation
GO:0018149 peptide cross-linking

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0106 Calcium
KW-0479 Metal-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR034810 Factor_XIII_A
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR038765 Papain-like_cys_pep_sf
IPR002931 Transglutaminase-like
IPR036985 Transglutaminase-like_sf
IPR023608 Transglutaminase_animal
IPR013808 Transglutaminase_AS
IPR008958 Transglutaminase_C
IPR036238 Transglutaminase_C_sf
IPR001102 Transglutaminase_N

PROSITE

PROSITE ID PROSITE Term
PS00547 TRANSGLUTAMINASES

Pfam

Pfam ID Pfam Term
PF00927 Transglut_C
PF01841 Transglut_core
PF00868 Transglut_N