| Tag | Content |
|---|---|
| Uniprot ID | F1Q5U5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000110348 |
| Ensembl nucleotide ID | ENSDARG00000027419 |
| Gene name | Glutamate decarboxylase 1b |
| Gene symbol | gad1b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASSAPSSSA GDMDPNTANL RQPATTSDAW YGVAHGCTRK LGMKICGFLQ KNNSLDEKSR 60 MVGSFKESAK NQMSCDNNER FTRDETDFSN LFARDLLPAK NGEEPTIQFL LEVVEILTNY 120 VRKTFDRSTK VLDFHHPHQL LEGMEGFNLE LSDQPESLEQ ILVDCRDTLK YGVRTGHPRF 180 FNQLSSGLDI IGLAGEWLTS TANTNMFTYE IAPVFVLMEQ LTLKKMREII GWPNGDGDAL 240 FSPGGAISNM YSVMVARYKY FPEVKTKGMS AAPRLVLFTS EHRTALLMRE SGSVLDHLID 300 GRPFLFSQSH YSIKKAGAVL GFGKENVILL KTDERGRVIP ADLEAKVIDA KQKGYVPLFV 360 NATAGTTVYG AFDPINDIAD ICEKYNLWLH VDGAWGGGLL MSRKHRHKLS GIERANSVTW 420 NPHKMMGVPL QCSAILVREK GILQGCNSMC AGYLFQPDKQ YDVTYDTGDK AIQCGRHVDI 480 FKFWLMWKAK GTIGFEQHID RCLELSEYLY NKIKNREGYE MVFEGQPQHT NVCFWYIPPS 540 LRGMPNGDER REKLHRVAPK IKAMMMECGT TMVGYQPQGD KVNFFRMVVS NHAVTKSDID 600 FLIDEIERLG QDL 613 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD1 | 517552 | Q0VCA1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | J9P2A8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | A0A452F295 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | 100052860 | F6ZIC0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 2571 | Q99259 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gad1 | 14415 | P48318 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD1 | 468557 | Q5IS68 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 396928 | P48319 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 100344727 | G1T3T2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad1 | 24379 | P18088 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad1b | F1Q5U5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016831 | carboxy-lyase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0009449 | gamma-aminobutyric acid biosynthetic process |
| GO:0042136 | neurotransmitter biosynthetic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |