| Tag | Content |
|---|---|
| Uniprot ID | G1T3T2 |
| Entrez ID | 100344727 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_002712277.3 |
| Ensembl protein ID | ENSOCUP00000010894 |
| Ensembl nucleotide ID | ENSOCUG00000012644 |
| Gene name | Glutamate decarboxylase 1 |
| Gene symbol | GAD1 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASSTPSSSA TSSNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF LQRTNSLEEK 60 SRLVSAFRER QSSKNLLSCE NSDREARFRR TETDFSNLFA RDLLPAKNGE EQTVQFLLEV 120 VDILLNYVRK TFDRSTKVLD FHHPHQLLEG MEGFNLELSD HPESLEQILV DCRDTLKYGV 180 RTGHPRFFNQ LSTGLDIIGL AGEWLTSTAN TNMFTYEIAP VFVLMEQITL KKMREIVGWS 240 SKDGDGIFSP GGAISNLYSI MAARYKYFPE VKTKGMAAVP KLVLFTSEHS HYSIKKAGAA 300 LGFGTDNVIL IKCNERGKII PADLEAKILE SKQKGYVPLY VNATAGTTVY GAFDPIQEIA 360 DLCEKYNLWL HVDAAWGGGL LMSRKHRHKL SGIERANSVT WNPHKMMGVL LQCSAILVRE 420 KGILQGCNQM CAGYLFQPDK QYDVSYDTGD KAIQCGRHVD IFKFWLMWKA KGTVGFENQI 480 NKCLELAEYL YAKIKNREEF EMVFDGEPEH TNVCFWYIPP SLRGVPDSPE RREKLHRVAP 540 KIKALMMESG TTMVGYQPQG DKANFFRMVI SNPAATQSDI DFLIEEIERL GQDL 594 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD1 | 517552 | Q0VCA1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | J9P2A8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | A0A452F295 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | 100052860 | F6ZIC0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 2571 | Q99259 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gad1 | 14415 | P48318 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD1 | 468557 | Q5IS68 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 396928 | P48319 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 100344727 | G1T3T2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad1 | 24379 | P18088 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad1b | F1Q5U5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016831 | carboxy-lyase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019752 | carboxylic acid metabolic process |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |