| Tag | Content |
|---|---|
| Uniprot ID | J9P2A8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCAFP00000039685 |
| Ensembl nucleotide ID | ENSCAFG00000012560 |
| Gene name | Glutamate decarboxylase 1 |
| Gene symbol | GAD1 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASSTPSSSA TSSNAGADPN TANLRPTTYD TWCGVAHGCT RKLGLKICAF FETANILENK 60 YLQINAFKHN RDLPPLLSCD VHDPPRILVS TKTAVGSLKA RYLLPAKNGE EQTVQFLLEV 120 VDILLNYVRK TFDRSTKVLD FHHPHQLLEG MEGFNLELSD HPESLEQILV DCRDTLKYGV 180 RTGHPRFFNQ LSTGLDIIGL AGEWLTSTAN TNMFTYEIAP VFVLMEQITL KKMREIVGWS 240 SKDGDGIFSP GGAISNMYSI MAARYKFFPE VKTKGMAAVP KLVLFTSEHS HYSIKKAGAA 300 LGFGTDNVIL IKCNERGKII PADLEAKILE AKQKGYVPLY VNATAGTTVY GAFDPIQEIA 360 DICEKYNLWL HVDAAWGGGL LMSRKHRHKL SGIERANSVT WNPHKMMGVL LQCSAILVKE 420 KGILQGCNQM CAGYLFQPDK QYDVSYDTGD KAIQCGRHVD IFKFWLMWKA KGTVGFENQI 480 NKCLELAEYL YAKIKNREEF EMVFDGEPEH TNVCFWYIPQ SLRGIPDSPE RREKLHRKVA 540 PKIKALMMES GTTMVGYQPQ GDKANFFRMV ISNPAATQSD IDFLIEEIER LGQDL 595 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD1 | 517552 | Q0VCA1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | J9P2A8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | A0A452F295 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | 100052860 | F6ZIC0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 2571 | Q99259 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gad1 | 14415 | P48318 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD1 | 468557 | Q5IS68 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 396928 | P48319 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 100344727 | G1T3T2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad1 | 24379 | P18088 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad1b | F1Q5U5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0043679 | axon terminus |
| GO:0005938 | cell cortex |
| GO:0060077 | inhibitory synapse |
| GO:0048786 | presynaptic active zone |
| GO:0004351 | glutamate decarboxylase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019752 | carboxylic acid metabolic process |
| GO:0035641 | locomotory exploration behavior |
| GO:0035176 | social behavior |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |