| Tag | Content |
|---|---|
| Uniprot ID | F6ZIC0 |
| Entrez ID | 100052860 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001498256.4 |
| Ensembl protein ID | ENSECAP00000011080 |
| Ensembl nucleotide ID | ENSECAG00000012405 |
| Gene name | Glutamate decarboxylase 1 |
| Gene symbol | GAD1 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MASSTPSSSA TASNAGADPN TTNLRPTTYD TWCGVAHGCT RKLGLKICGF LQRTNSLEEK 60 SRLVSAFKER QSSKNLLSCE NSDRDGRFRR TETDFSNLFA RDLLPAKNGE EQTVQFLLEV 120 VDILLNYVRK TFDRSTKVLD FHHPHQLLEG MEGFNLELSD HPESLEQILV DCRDTLKYGV 180 RTGHPRFFNQ LSTGLDIIGL AGEWLTSTAN TNMFTYEIAP VFVLMEQITL KKMREIVGWS 240 SKDGDGIFSP GGAISNMYSI MAARYKYFPE VKTKGMAAVP KLVLFTSEHS HYSIKKAGAA 300 LGFGTDNVIL IKCNERGKII PADLQAKILE AKQKGYVPLY VNATAGTTVY GAFDPIQEIA 360 DICEKYNLWL HVDAAWGGGL LMSRKHRHKL SGIERADSVT WNPHKMMGVL LQCSAILVKE 420 KGILQGCNQM CAGYLFQPDK QYDVSYDTGD KAIQCGRHVD IFKFWLMWKA KGTVGFENQI 480 NKCLELAEYL YAKIKNREEF EMVFDGEPEH TNVCFWYIPQ SLRGVPDSPE RREKLHRVAP 540 KIKALMMESG TTMVGYQPQG DKANFFRMVI SNPAATQSDI DFLIEEIERL GQDL 594 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GAD1 | 517552 | Q0VCA1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | J9P2A8 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | A0A452F295 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GAD1 | 100052860 | F6ZIC0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 2571 | Q99259 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Gad1 | 14415 | P48318 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GAD1 | 468557 | Q5IS68 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 396928 | P48319 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | GAD1 | 100344727 | G1T3T2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gad1 | 24379 | P18088 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | gad1b | F1Q5U5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0043679 | axon terminus |
| GO:0005938 | cell cortex |
| GO:0060077 | inhibitory synapse |
| GO:0048786 | presynaptic active zone |
| GO:0004351 | glutamate decarboxylase activity |
| GO:0030170 | pyridoxal phosphate binding |
| GO:0019752 | carboxylic acid metabolic process |
| GO:0035641 | locomotory exploration behavior |
| GO:0035176 | social behavior |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00392 | DDC_GAD_HDC_YDC |
| Pfam ID | Pfam Term |
|---|---|
| PF00282 | Pyridoxal_deC |