| Tag | Content |
|---|---|
| Uniprot ID | F1R3W0; Q5RIQ5; Q6DRH0; |
| Entrez ID | |
| Genbank protein ID | AAT68107.1; CAI21238.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000049223 |
| Ensembl nucleotide ID | ENSDARG00000028937 |
| Gene name | TATA box-binding protein-associated factor RNA polymerase I subunit B |
| Gene symbol | taf1b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment (By similarity). |
| Sequence | MDEQITGGYS EPCGQCAAVD WGVSDEGQFF CKSCHNVIEK IREVEDVTSL HHKHGRISIV 60 RKPKKKKHDS EREWLVCEGF QFILKHQAKA LVSLGVCMKF ETEVLWNFWK RYLQNTRQAF 120 TENPVSTARF EVFMKSQSGS ESDTQSHQSC YSEASSDTEM SVSGISVDGR SAVSSESLHS 180 IPQKGRRGRV SNLMSMPRTL AMCYLALLWV REAITLTDLL RMVAEGHIPY LHLHETFPAE 240 MRMFGKDVQI FRVLFFPSYA FIKKEALVLA KIMKLPSFPT ISQDCLFHPV PLTVRYLLEA 300 NLPDALHVWV QKVITGAGMD SDSFLTFDPT DKKPHLLSYD VQAVAVIIVA MKLLFKLDDH 360 VEWKLSHDAA KKKNNKVFSL ERWFNIVQPV LEQARLKEEQ EEARRQWNFA NPFITNLKRK 420 SLVLKKRRVT DHLQQRFQKF ADPAPEQSTS TTNSHTSFRF SWGEEEGSDG PSMFNQNLDC 480 TVKAKAVNGL ANQRYWHPEL RICPENKCVS HFSKFEPSLP RMFVWVLDLF SFILGVLQSD 540 VYEEVLNVER RFLKKNYRLD SRLTSSHLKK KKGPIL 576 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TAF1B | 511236 | Q1JQD6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TAF1B | 100684854 | F1PFZ2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | TAF1B | 102186603 | A0A452EIN8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TAF1B | 9014 | Q53T94 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Taf1b | 21340 | P97358 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | TAF1B | 459022 | H2QHF2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | TAF1B | F1SA99 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Taf1b | 690450 | D3ZYB7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | taf1b | F1R3W0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0070860 | RNA polymerase I core factor complex |
| GO:0005668 | RNA polymerase transcription factor SL1 complex |
| GO:0046872 | metal ion binding |
| GO:0001164 | RNA polymerase I core promoter sequence-specific DNA binding |
| GO:0042790 | nucleolar large rRNA transcription by RNA polymerase I |
| GO:0001188 | RNA polymerase I preinitiation complex assembly |
| Pfam ID | Pfam Term |
|---|---|
| PF11781 | zf-RRN7 |