Gene: HKDC1

Basic information

Tag Content
Uniprot ID F1SUF3
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000010930
Ensembl nucleotide ID ENSSSCG00000010252
Gene name Hexokinase domain containing 1
Gene symbol HKDC1
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFAVHLMAFY FTKLKEDQIK KVDRFLYHMR LSDETLLDIM ARFQAEMQKG LGKDTNPTAS 60
VKMLPTFVRA IPDGSENGEF LSLDLGGSKF RVLKVQVSEE GKRNVQMESQ FYPTPNEIIR 120
GNGTELFEYV ADCLADFMET KGLKQKKLPL GLTFSFPCRQ TKLEEGVLLS WTKKFKARGV 180
QDTDIVSSLS NAMRKHKDID VDILALVNDT VGTMMTCAYD DPYCEVGVII GTGTNACYME 240
DMSNIDLVEG DEGRMCINTE WGAFGDDGAL EDIRTEFDRE LDLGSLNPGK QLFEKMISGL 300
YLGELVRLIL LKMAKTGLLF GGEKSSALHI KGKIETRHVA AMERYKEGLA NTREILTDLG 360
LEPSEADCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN KKLVRLRTTV GMDGTLYKIH 420
PQYPKRLHKV VRKLVPNCDV RFLLSESGSA KGAAMVTAVA SRVQAQRKQI DKMLALFQLT 480
PEQLVGVRDK MRVELEYGLK KDTHPLATVK MLPTYVRGMP DGTEKGKFLA LDLGGTNFRV 540
LLVKIRSGRR SVRMYNKIFA IPLEIMQGTG EELFDHIVQC IADFLDYMGL KGAQLPLGFT 600
FSFPCRQASI DKGTLIEWTK GFKATDCEGE DVVDMLREAI KRRNEFDLDI VAVVNDTVGT 660
MMTCGYEDRN CEIGLIAGTG SNMCYMEEMK NIELVEGNEG KMCINTEWGG FGDNGCLDDI 720
RTQYDKEVDE GSLNPGKQRY EKMTSGMYLG EIVRQILIDL TKQGLLFRGQ ISERLRTRGI 780
FETKFLSQIE SFSRILQETV KELAPRCDVM FMLSEDGSGK GAALITAVAK RLQQARKDN 839

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHKDC1489019J9JHN0Canis lupus familiarisPredictionMore>>
1:1 orthologHKDC1102189736A0A452E4U0Capra hircusPredictionMore>>
1:1 orthologHKDC1100072686A0A3Q2HML6Equus caballusPredictionMore>>
1:1 orthologHKDC180201Q2TB90Homo sapiensPublicationMore>>
1:1 orthologHkdc1216019Q91W97Mus musculusPredictionMore>>
1:1 orthologHKDC1450504H2Q205Pan troglodytesPredictionMore>>
1:1 orthologHKDC1F1SUF3Sus scrofaPredictionMore>>
1:1 orthologHKDC1100345105G1SMV5Oryctolagus cuniculusPredictionMore>>
1:1 orthologM0R3X7Rattus norvegicusPredictionMore>>
1:1 orthologhkdc1321224B8A5H6Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005623 cell
GO:0005524 ATP binding
GO:0005536 glucose binding
GO:0004396 hexokinase activity
GO:0001678 cellular glucose homeostasis
GO:0006096 glycolytic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0324 Glycolysis
KW-0418 Kinase
KW-0547 Nucleotide-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0808 Transferase

Interpro

InterPro ID InterPro Term
IPR043129 ATPase_NBD
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N

PROSITE

PROSITE ID PROSITE Term
PS00378 HEXOKINASE_1
PS51748 HEXOKINASE_2

Pfam

Pfam ID Pfam Term
PF00349 Hexokinase_1
PF03727 Hexokinase_2