Gene:

Basic information

Tag Content
Uniprot ID M0R3X7
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSRNOP00000064051
Ensembl nucleotide ID ENSRNOG00000049045
Gene name Uncharacterized protein
Gene symbol
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFAVHLVAFY FTKLKEDQIK KVDRFLYHMR LSDETLVDIM ARFQAEMEKG LGKDTNPTAS 60
VKMLPTFVRA IPDGSENGEF LSLDLGGSKF RVLKVQVSEE GKQNVQMESQ FYPMPNEITR 120
GNGTELFDYV ADCLADFMKT KDLTHKKLPL GFTFSFPCRQ NKLEEGFLLS WTKKFKARGV 180
QDTDVVNRLA TAMKKHKDLD VDILALVNDT VGTMMTCAYD DPNCEVGVII GTGTNACYME 240
DMSNIDLVEG DEGRMCINTE WGAFGDDGTL EDIRTEFDRE LDLGSLNPGK QLFEKMISGL 300
YMGELVRLIL LKMAKVGLLF GGAKSSALHT KGKIETQHVA AMEMSKEGLA NTREILVDLG 360
LDPSESDCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN KKLARLRTTV GMDGTLYKTH 420
PQHTRRGHKG LDDLIPDGQT RRLQGERGDM RGEQPETSGR VQRQEKKVIE SELAMRGEGR 480
EESRETRRRA KTGQERGPRA RSHLPAWFQS LPLWLHSPYE HVGKGKMLGT DVFKGKVEVP 540
PGKTKTQMVK SLTGLFDNCR ESLRGHGEPL SFRRLCLLFP TPRTASSEST FLPYQSYPPF 600
PNRYEKMTSG MVTWGRLFQA DSGPGVSLET KSCLRLKVWD LSILLGIDQA SGSLNKCGYF 660
DPRGQTGFII GTGPGTCIME DQTLIKRVCG QKGRIIWEAR WKGFSDLQRL RGLSPSFDPV 720
LCISLIPSSP NRYEKMTSGM YLGEIVRRIL IDLTRQGLLF RGQISERLRT RGIFETKFLS 780
QIESDRLALL QVRRILQQLG LDSTCEDSIV VKEVCGAVSR RAAQMCGAGM AAIVEKRRED 840
QGLQHFKVTV GVDGTLYKLH PHFSRILQET VKDLAPQCDV TFMLSEDGSG KGAALITAVA 900
KRLQQLPKDN

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHKDC1489019J9JHN0Canis lupus familiarisPredictionMore>>
1:1 orthologHKDC1102189736A0A452E4U0Capra hircusPredictionMore>>
1:1 orthologHKDC1100072686A0A3Q2HML6Equus caballusPredictionMore>>
1:1 orthologHKDC180201Q2TB90Homo sapiensPublicationMore>>
1:1 orthologHkdc1216019Q91W97Mus musculusPredictionMore>>
1:1 orthologHKDC1450504H2Q205Pan troglodytesPredictionMore>>
1:1 orthologHKDC1F1SUF3Sus scrofaPredictionMore>>
1:1 orthologHKDC1100345105G1SMV5Oryctolagus cuniculusPredictionMore>>
1:1 orthologM0R3X7Rattus norvegicusPredictionMore>>
1:1 orthologhkdc1321224B8A5H6Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005623 cell
GO:0005829 cytosol
GO:0005739 mitochondrion
GO:0005524 ATP binding
GO:0008865 fructokinase activity
GO:0004340 glucokinase activity
GO:0005536 glucose binding
GO:0019158 mannokinase activity
GO:0001678 cellular glucose homeostasis
GO:0006096 glycolytic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0324 Glycolysis
KW-0418 Kinase
KW-0547 Nucleotide-binding
KW-1185 Reference proteome
KW-0808 Transferase

Interpro

InterPro ID InterPro Term
IPR043129 ATPase_NBD
IPR001312 Hexokinase
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N

PROSITE

PROSITE ID PROSITE Term
PS51748 HEXOKINASE_2

Pfam

Pfam ID Pfam Term
PF00349 Hexokinase_1
PF03727 Hexokinase_2