| Tag | Content |
|---|---|
| Uniprot ID | J9JHN0 |
| Entrez ID | 489019 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_546137.4 |
| Ensembl protein ID | ENSCAFP00000035961 |
| Ensembl nucleotide ID | ENSCAFG00000032754 |
| Gene name | Hexokinase domain containing 1 |
| Gene symbol | HKDC1 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFAIHLMAFY FSKLKEDQIK KVDRFLYHMR LSDETLLDIM ARFQAEMQKG LGKDTNPTAS 60 VKMLPTFVRA IPDGSENGEF LSLDLGGSKF RVLKVQVSEE GKRNVQMESQ FYPTPNEIIR 120 GNGSELFDYI ADCLADFMKT RGLKHKKFPL GLTFSFPCRQ TKLEEGILLS WTKKFKARGV 180 QDTDVVSCLT KAVKKHKDID VDILTLVNDT VGTMMTCAYD DPYCEVGVII GTGTNACYME 240 DMSNIDLVEG DEGRMCINTE WGAFGDDGTL EDIRTEFDRE LDLGSLNPGK QLFEKMISGL 300 YLGELVRIIL LKMAKAGLLF GGKKSSALHT KGKIETRHVA AMEKYKEGLA NTREILTDLG 360 LEPSEADCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN KKLERLRTTV GMDGTLYKIH 420 PQYPKRLHKV VRRLVPNCDV RFLLSESGST KGAAMVTAVA SRVQAQRKQI DKVLALFQLT 480 REQLMDVQGK MRREFEYGLK RDTHLMATVK MLPTYVCGMP DGTEKGKFLA LDLGGTNFRV 540 LLVKIRSGRR SVRMYNKIFA IPLEIMQGTG EELFDHIVQC IADFLDYMGL KGVQLPLGFT 600 FSFPCRQTSI DKGTLIEWTK GFKATDCEGE DVVDMLREAI KRRNEFDLDI VAVVNDTVGT 660 MMTCGHEDPN CEIGLIAGTG SNMCYMEEMR NIELVEGDEG KMCINTEWGG FGDNGCIDDI 720 RTQYDEKVDE GSLNPGKQRY EKMTSGMYLG EIVRQILIDL TKQGLLFRGQ ISERLRTRGI 780 FETKFLSQIE SDRLALLQVR SILQQLGLDS TCEDSIVVKE VCGAVSRRAA QLYGAGLAAV 840 VEKKREDQGL EYLKITVGVD GTLYKLHPHF SRILQETVKE LAPRCDVTLM LSEDGSGKGA 900 ALITAVAKRL QQAQKEN 917 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HKDC1 | 489019 | J9JHN0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 102189736 | A0A452E4U0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 100072686 | A0A3Q2HML6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 80201 | Q2TB90 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Hkdc1 | 216019 | Q91W97 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 450504 | H2Q205 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | F1SUF3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | HKDC1 | 100345105 | G1SMV5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | M0R3X7 | Rattus norvegicus | Prediction | More>> | ||||
| 1:1 ortholog | hkdc1 | 321224 | B8A5H6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005623 | cell |
| GO:0005829 | cytosol |
| GO:0005739 | mitochondrion |
| GO:0005524 | ATP binding |
| GO:0008865 | fructokinase activity |
| GO:0004340 | glucokinase activity |
| GO:0005536 | glucose binding |
| GO:0019158 | mannokinase activity |
| GO:0001678 | cellular glucose homeostasis |
| GO:0006096 | glycolytic process |