| Tag | Content |
|---|---|
| Uniprot ID | H2Q205 |
| Entrez ID | 450504 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016918464.1 |
| Ensembl protein ID | ENSPTRP00000004445 |
| Ensembl nucleotide ID | ENSPTRG00000002570 |
| Gene name | Hexokinase domain containing 1 |
| Gene symbol | HKDC1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFAVHLMAFY FSKLKEDQIK KVDRFLYHMR LSDDTLLDIM RRFRAEMEKG LAKDTNPTAA 60 VKMLPTFVRA IPDGSENGEF LSLDLGGSKF RVLKVQVAEE GKRHVQMESQ FYPTPNEIIR 120 GNGTELFEYV ADCLADFMKT KDLKHKKLPL GLTFSFPCRQ TKLEEGVLLS WTKKFKARGV 180 QDTDVVSHLT KAMRRHKDMD VDILALVNDT VGTMMTCAYD DPYCEVGVII GTGSNACYME 240 DMSNIDLVEG DEGRMCINTE WGAFGDDGAL GDIRTEFDRE LDLGSLNPGK QLFEKMISGL 300 YLGELVRLIL LKMAKAGLLF GGEKSSALHT KGKIETRHVA AMEKYKEGLA NTREILVDLG 360 LEPSEADCIA VQHVCTIVSF RSANLCAAAL AAILTRLREN KKVERLRTTV GMDGTLYKIH 420 PQYPKRLHKV VRKLVPSCDV RFLLSESGST KGAAMVTAVA SRVQAQRKQI DRVLALFQLT 480 REQLVDVQAK MRAELEYGLK KKSHGLATVR MLPTYVCGLP DGTEKGKFLA LDLGGTNFRV 540 LLVKIRSGRR SVRMYNKIFA IPLEIMQGTG EELFDHIVQC IADFLDYMGL KGASLPLGFT 600 FSFPCRQMSI DKGTLIGWTK GFKATDCEGE DVVDMLREAI KRRNEFDLDI VAVVNDTVGT 660 MMTCGYEDPN CEIGLIAGTG SNMCYMEDMR NIEMVEGGEG KMCINTEWGG FGDNGCIDDI 720 RTRYDTEVDE GSLNPGKQRY EKMTSGMYLG EIVRQILIDL TKQGLLFRGQ ISERLRTRGI 780 FETKFLSQIE SDRLALLQVR RILQQLGLDS TCEDSIVVKE VCGAVSRRAA QLCGAGLAAI 840 VEKRREDQGL EHLRITVGVD GTLYKLHPHF SRILQETVKK LAPRCDVTFM LSEDGSGKGA 900 ALITAVAKRL QQAQKEN 917 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HKDC1 | 489019 | J9JHN0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 102189736 | A0A452E4U0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 100072686 | A0A3Q2HML6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 80201 | Q2TB90 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Hkdc1 | 216019 | Q91W97 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | 450504 | H2Q205 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HKDC1 | F1SUF3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | HKDC1 | 100345105 | G1SMV5 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | M0R3X7 | Rattus norvegicus | Prediction | More>> | ||||
| 1:1 ortholog | hkdc1 | 321224 | B8A5H6 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005623 | cell |
| GO:0005829 | cytosol |
| GO:0005739 | mitochondrion |
| GO:0005524 | ATP binding |
| GO:0008865 | fructokinase activity |
| GO:0004340 | glucokinase activity |
| GO:0005536 | glucose binding |
| GO:0019158 | mannokinase activity |
| GO:0001678 | cellular glucose homeostasis |
| GO:0006096 | glycolytic process |