Gene: dlx2a

Basic information

Tag Content
Uniprot ID F6NKE2
Entrez ID 30574
Genbank protein ID
Genbank nucleotide ID NM_131311.2
Ensembl protein ID ENSDARP00000103004
Ensembl nucleotide ID ENSDARG00000079964
Gene name Homeobox protein Dlx2a
Gene symbol dlx2a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MKNMTGVFDS LSTDMHSNQI TSSSYHSLHK SQESPTLPVS TATDSSYYNN NNQQCAGSPY 60
GQISSYQYQN NSMNSVQYNT KSYELGFGNA FGPYGTYGSC SSPTPADAEK EESEPEIRMV 120
NGKPKKVRKP RTIYSSFQLA ALQRRFQKTQ YLALPERAEL AASLGLTQTQ VKIWFQNRRS 180
KFKKLWKSGE IPPEQHVASS ESPPHPSPPL AAAWDFAHSQ RMNTVNSGLS QSSPPNTTTP 240
SFLTNYPWYS STNSAAHLQP PLHHNTTVSA GTIF 274

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologDLX2528490E1BCF7Bos taurusPredictionMore>>
1:1 orthologDLX2100856541E2R5E5Canis lupus familiarisPredictionMore>>
1:1 orthologDLX2102188447A0A452FZW1Capra hircusPredictionMore>>
1:1 orthologDLX21746Q07687Homo sapiensPredictionMore>>
1:1 orthologDlx213392P40764CPOMus musculusPublicationMore>>
1:1 orthologDLX2459741K7AA60Pan troglodytesPredictionMore>>
1:1 orthologDLX2100523029F1S082Sus scrofaPredictionMore>>
1:1 orthologDlx2296499G3V668Rattus norvegicusPredictionMore>>
1:1 orthologdlx2a30574F6NKE2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR022135 Distal-less_N
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR000047 HTH_motif

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF12413 DLL_N
PF00046 Homeodomain