| Tag | Content |
|---|---|
| Uniprot ID | G3V668 |
| Entrez ID | 296499 |
| Genbank protein ID | EDL79105.1 |
| Genbank nucleotide ID | NM_001191746.1 |
| Ensembl protein ID | ENSRNOP00000002076 |
| Ensembl nucleotide ID | ENSRNOG00000001519 |
| Gene name | Distal-less homeobox 2 |
| Gene symbol | Dlx2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTGVFDSLVA DMHSTQITAS STYHQHQQPP SGAGAGSGGS SNSSSSNSNL HKPQESPTLP 60 VSTATDSSYY TNQQHPAGGG GGGASPYAHM GSYQYHASGL NNVSYSAKSS YDLGYTAAYT 120 SYAPYGTSSS PVNNEPDKED LEPEIRIVNG KPKKVRKPRT IYSSFQLAAL QRRFQKTQYL 180 ALPERAELAA SLGLTQTQVK IWFQNRRSKF KKMWKSGEIP TEQHPGASAS PPCASPPVSA 240 PASWDFGAQQ RMAGGGPGSG GSGAGSSGSS PSSAASAFLG NYPWYHQASG SASHLQATAP 300 LLHPSQTPQA HHHHHHHHHA GGGAPVSAGT IF 332 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DLX2 | 528490 | E1BCF7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | DLX2 | 100856541 | E2R5E5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | DLX2 | 102188447 | A0A452FZW1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | DLX2 | 1746 | Q07687 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dlx2 | 13392 | P40764 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | DLX2 | 459741 | K7AA60 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DLX2 | 100523029 | F1S082 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Dlx2 | 296499 | G3V668 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dlx2a | 30574 | F6NKE2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003682 | chromatin binding |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0003727 | single-stranded RNA binding |
| GO:0048755 | branching morphogenesis of a nerve |
| GO:0051216 | cartilage development |
| GO:0021893 | cerebral cortex GABAergic interneuron fate commitment |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0021766 | hippocampus development |
| GO:0045746 | negative regulation of Notch signaling pathway |
| GO:0048715 | negative regulation of oligodendrocyte differentiation |
| GO:0046533 | negative regulation of photoreceptor cell differentiation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0042475 | odontogenesis of dentin-containing tooth |
| GO:0021772 | olfactory bulb development |
| GO:1902871 | positive regulation of amacrine cell differentiation |
| GO:0009954 | proximal/distal pattern formation |
| GO:0021882 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment |
| GO:0021544 | subpallium development |