| Tag | Content |
|---|---|
| Uniprot ID | F7VJQ5 |
| Entrez ID | 100034503 |
| Genbank protein ID | DAA34835.1 |
| Genbank nucleotide ID | XM_005159580.3 |
| Ensembl protein ID | ENSDARP00000124302 |
| Ensembl nucleotide ID | ENSDARG00000061974 |
| Gene name | Grainyhead-like 2b protein |
| Gene symbol | grhl2b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSQETDSKRL VVVVPNEPSF HQRRPYTSED EAWRSYLENP LTAATKAMMS INGDEDSAAA 60 LGLLYEYYKV PKDKRVPISK VVEMSDEPEK RSTPVGNSSQ MEPETVDNHV QVLKSVPVNL 120 SLNTDHQDNK REQYSVPAGE SGTAAVVKAE AHTAVFMTSG GHYRTEGEEQ MRVICEQTHS 180 FDTSTINHSA YGKDDHRSSP ESTYEDDSNE KYRSSSIGPD DFIFDQSHML DTFQYTLEAS 240 KSLRQKQGEG PMTYLNKGQF YAITLSETSA NKRLRHPISK VRSVVMVVFS EDKNRDEQLK 300 YWKYWHSRQH TAKQRVLDIA DYKESFNTIG NIEEIAYNAV SFTWDLNEEA KIFITVNCLS 360 TDFSSQKGVK GLPLMIQIDT YSYNNRSNKP LHRAYCQIKV FCDKGAERKI RDEERKQNRK 420 KTKGKDGGSG TVTVPKKCDS TLFKTMTDLD AQPVLFIPDV HFGNLQRAGQ VFAFNTEEIE 480 CEGSVLVKRM FRSSEEDFCP PPHKQLREDT QKRVLLYVRK ESDEVFDALM LRSPTVRGLM 540 DAISEKYGVP IDRMAKIYKK SKKGILVNMD DNIIEHYSNE DTFILNIESY ADAYKITLTE 600 I 601 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GRHL2 | A0A452F1Z6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | GRHL2 | 100056140 | F7BG04 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | GRHL2 | 79977 | Q6ISB3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Grhl2 | 252973 | Q8K5C0 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | GRHL2 | 464320 | H2QWI7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GRHL2 | F1S0Q6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Grhl2 | 299979 | B5DEI9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | grhl2b | 100034503 | F7VJQ5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000976 | transcription regulatory region sequence-specific DNA binding |
| GO:0060561 | apoptotic process involved in morphogenesis |
| GO:0007420 | brain development |
| GO:0048839 | inner ear development |
| GO:0030917 | midbrain-hindbrain boundary development |
| GO:0021555 | midbrain-hindbrain boundary morphogenesis |
| GO:0021915 | neural tube development |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR007604 | CP2 |
| Pfam ID | Pfam Term |
|---|---|
| PF04516 | CP2 |