| Tag | Content |
|---|---|
| Uniprot ID | H2QUH0; A0A2J8K9L7; |
| Entrez ID | 463371 |
| Genbank protein ID | JAA30838.1; JAA09418.1; JAA41359.1; JAA09416.1; JAA09417.1; JAA20494.1; JAA30839.1; JAA20496.1; JAA20492.1; JAA41361.1; JAA41360.1; |
| Genbank nucleotide ID | XM_519063.5 |
| Ensembl protein ID | ENSPTRP00000093770 |
| Ensembl nucleotide ID | ENSPTRG00000044337 |
| Gene name | Inhibin subunit beta A |
| Gene symbol | INHBA |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPLLWLRGFL LASCWIIVRS SPTPGSEGHS AAPDCPSCAL AALPKDVPNS QPEMVEAVKK 60 HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVGKVGENGY VEIEDDIGRR AEMNELMEQT 120 SEIITFAESG TARKTLHFEI SKEGSDLSVV ERAEVWLFLK VPKANRTRTK VTIRLFQQQK 180 HPQGSLDTGE EAEEVGLKGE RSELLLSEKV VDARKSTWHV FPVSSSIQRL LDQGKSSLDV 240 RIACEQCQES GASLVLLGKK KKKEEEGEGK KKGGGEGGAG ADEEKEQSHR PFLMLQARQS 300 EDHPHRRRRR GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG 360 TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV 420 EECGCS 426 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | INHBA | 281867 | P07995 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 483245 | E2QW13 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 100860960 | F8SXW5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 3624 | P08476 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Inhba | 16323 | Q04998 | CPO | E12.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | INHBA | 463371 | H2QUH0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 397093 | P03970 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Inhba | 29200 | P18331 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | inhbaa | 30072 | Q8QGE3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0043509 | activin A complex |
| GO:0005615 | extracellular space |
| GO:0043512 | inhibin A complex |
| GO:0048471 | perinuclear region of cytoplasm |
| GO:0005125 | cytokine activity |
| GO:0008083 | growth factor activity |
| GO:0005179 | hormone activity |
| GO:0042802 | identical protein binding |
| GO:0017046 | peptide hormone binding |
| GO:0070699 | type II activin receptor binding |
| GO:0032924 | activin receptor signaling pathway |
| GO:0007050 | cell cycle arrest |
| GO:0035987 | endodermal cell differentiation |
| GO:0097191 | extrinsic apoptotic signaling pathway |
| GO:0061029 | eyelid development in camera-type eye |
| GO:0000082 | G1/S transition of mitotic cell cycle |
| GO:0097154 | GABAergic neuron differentiation |
| GO:0001942 | hair follicle development |
| GO:0002244 | hematopoietic progenitor cell differentiation |
| GO:0042541 | hemoglobin biosynthetic process |
| GO:0008584 | male gonad development |
| GO:0048333 | mesodermal cell differentiation |
| GO:0030308 | negative regulation of cell growth |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0051799 | negative regulation of hair follicle development |
| GO:0042476 | odontogenesis |
| GO:0001541 | ovarian follicle development |
| GO:0045648 | positive regulation of erythrocyte differentiation |
| GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0060279 | positive regulation of ovulation |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0042701 | progesterone secretion |
| GO:0046880 | regulation of follicle-stimulating hormone secretion |
| GO:0060021 | roof of mouth development |
| GO:0060395 | SMAD protein signal transduction |
| GO:0021773 | striatal medium spiny neuron differentiation |