| Tag | Content |
|---|---|
| Uniprot ID | Q8QGE3 |
| Entrez ID | 30072 |
| Genbank protein ID | AAH66402.1; AAL85328.1; AAH56742.1; |
| Genbank nucleotide ID | NM_130916.1 |
| Ensembl protein ID | ENSDARP00000006400 |
| Ensembl nucleotide ID | ENSDARG00000012671 |
| Gene name | Activin beta A subunit |
| Gene symbol | inhbaa |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSPLPLLSGI LLLLIRSCSL SAMVTKGSLP MSEQQAGATV CPSCALARFR KGVSESEDEG 60 AQQDVVEAVK RHILNMLHLQ ERPNITHPVP RAALLNAIRK VHVGRVAKDG SVLIEDEASN 120 RAETEQAEQT EIITFAETGE APGIVNFLIS KEGGEMSVVD QANVWIFLRL PKGNRTRANV 180 NIRLLLQQGA GEKILAEKSV DTRRSGWHTF PASESVQSLL QRGGSTLSLR VSCPLCADAR 240 ATPVLVSPGG SEREQSHRPF LMAVVRQMDE LSLRRRRKRG LECDGKARVC CKRQFYVNFK 300 DIGWNDWIIA PSGYHANYCE GDCASNVASI TGNSLSFHST VISHYRIRGY SPFTNIKSCC 360 VPTRLRAMSM LYYNEEQKIV KKDIQNMIVE ECGCS 395 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | INHBA | 281867 | P07995 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 483245 | E2QW13 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 100860960 | F8SXW5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 3624 | P08476 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Inhba | 16323 | Q04998 | CPO | E12.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | INHBA | 463371 | H2QUH0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | INHBA | 397093 | P03970 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Inhba | 29200 | P18331 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | inhbaa | 30072 | Q8QGE3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0005125 | cytokine activity |
| GO:0008083 | growth factor activity |
| GO:0110021 | cardiac muscle myoblast proliferation |
| GO:0031101 | fin regeneration |
| GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation |
| GO:0060395 | SMAD protein signal transduction |
| Pfam ID | Pfam Term |
|---|---|
| PF00019 | TGF_beta |