| Tag | Content |
|---|---|
| Uniprot ID | P03970 |
| Entrez ID | 397093 |
| Genbank protein ID | CAA27020.1 |
| Genbank nucleotide ID | NM_214028.1 |
| Ensembl protein ID | ENSSSCP00055006693; ENSSSCP00045018828; ENSSSCP00070029068; ENSSSCP00070029074; ENSSSCP00000051495; ENSSSCP00050012980; ENSSSCP00035020976; |
| Ensembl nucleotide ID | ENSSSCG00045016024; ENSSSCG00055004286; ENSSSCG00000035077; ENSSSCG00070017615; ENSSSCG00035039272; ENSSSCG00050023033; |
| Gene name | Inhibin beta A chain |
| Gene symbol | INHBA |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Sequence | MPLLWLRGFL LASCWIIVRS SPTPGSGGHS AAPDCPSCAL ATLPKDVPNS QPEMVEAVKK 60 HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVGKVGENGY VELEDDIGRR AEMNELMEQT 120 SEIITFAEAG TARKTLRFEI SKEGSDLSVV ERAEIWLFLK VPKANRTRTK VSIRLFQQQR 180 RPQGSADAGE EAEDVGFPEE KSEVLISEKV VDARKSTWHI FPVSSSIQRL LDQGKSALDI 240 RTACEQCHET GASLVLLGKK KKKEEEAEGR KRDGEGAGVD EEKEQSHRPF LMLQARQSEE 300 HPHRRRRRGL ECDGKVNICC KKQFFVSFKD IGWNDWIIAP SGYHANYCEG ECPSHIAGTS 360 GSSLSFHSTV INHYRMRGHS PFANLKSCCV PTKLRPMSML YYDDGQNIIK KDIQNMIVEE 420 CGCS 424 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.