| Tag | Content |
|---|---|
| Uniprot ID | H2R877; A0A2J8QWF2; |
| Entrez ID | 469651 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001009122.2 |
| Ensembl protein ID | ENSPTRP00000051292 |
| Ensembl nucleotide ID | ENSPTRG00000001883 |
| Gene name | Renin |
| Gene symbol | REN |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDGWRRMPRW GLLLLLWGSC TFGLPTDTTT FKRIFLKRMP SIRESLKERG VDMARLGLEW 60 SQPMKRLTLG NTTSSVILTN YMDTQYYGEI GIGTPPQTFK VVFDTGSSNV WVPSSKCSRL 120 YTACVYHKLF DASDSSSYKH NGTELTLRYS TGTVSGFLSQ DIITVGGITV TQMFGEVTEM 180 PALPFMLAEF DGVVGMGFIE QAIGRVTPIF DNIISQGVLK EDVFSFYYNR DSENSQSLGG 240 QIVLGGSDPQ HYEGNFHYIN LIKTGVWQIQ MKGVSVGSST LLCEDGCLAL VDTGASYISG 300 STSSIEKLME ALGAKKRLFD YVVKCNEGPT LPDISFHLGG KEYTLTSADY VFQESYSSKK 360 LCTLAIHAMD IPPPTGPTWA LGATFIRKFY TEFDRRNNRI GFALAR 406 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | REN | 403838 | Q6DYE7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | REN | A0A452ERZ4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | REN | 5972 | P00797 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Ren1 | 19701 | P06281 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | REN | 469651 | H2R877 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | REN | A0A287APG1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Ren1 | 24715 | P08424 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ren | Q6XQJ0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0045177 | apical part of cell |
| GO:0005615 | extracellular space |
| GO:0004190 | aspartic-type endopeptidase activity |
| GO:0005102 | signaling receptor binding |
| GO:0002003 | angiotensin maturation |
| GO:0048469 | cell maturation |
| GO:0042756 | drinking behavior |
| GO:0009755 | hormone-mediated signaling pathway |
| GO:0008584 | male gonad development |
| GO:0001823 | mesonephros development |
| GO:0006508 | proteolysis |
| GO:0043408 | regulation of MAPK cascade |
| GO:0002018 | renin-angiotensin regulation of aldosterone production |