| Tag | Content |
|---|---|
| Uniprot ID | P20909; F1LSI4; Q62750; Q63391; Q63392; Q63393; Q8VBY8; Q920Z7; Q920Z8; Q920Z9; Q921A0; Q921A1; |
| Entrez ID | 25654 |
| Genbank protein ID | AAK83569.2; AAK83571.2; AAK83568.2; AAK83570.2; AAK83682.1; AAA92359.3; AAA92360.1; AAA92358.3; |
| Genbank nucleotide ID | NM_013117.1; XM_006233210.3; |
| Ensembl protein ID | ENSRNOP00000061595 |
| Ensembl nucleotide ID | ENSRNOG00000023148 |
| Gene name | Collagen alpha-1(XI) chain |
| Gene symbol | Col11a1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. |
| Sequence | MEPWSRWKTK RWIWDLTIST LVLTFLFQAR EVRGAAPVDI LKALDFHNSP VGISKTTGFC 60 TSRKNSKDPD IAYRVTEEAQ ISAPTKQLFP GGIFPQDFSI LFTIKPKKGT QAFLLSLYNE 120 HGIQQLGVEV GRSPVFLFED HTGKPTPENY PLFSTVNIAD GKWHRVAISV EKKTVTMIVD 180 CKKKITKPLD RSERSIVDTN GIMVFGTRIL ETDVFQGDIQ QFLITGDPKA AYDYCDHYSP 240 DCDLTSKAAQ AQEPHIDEYA PEDIIEYDYE YGETDYKEAE SVTEMPTVTE ETVAQTEANI 300 VDDFQDYNYG TMETYQTESP RRVSGSNEPN PVEEGFTEEY LTGEDYDVQR NISEDILYGN 360 KGIDGRDSDL LVDGDLGEYD FYEYKEYEER TTTSPNEEFG PGVPAETDFT ETSINGHGAY 420 GEKGQKGEPA VVEPGMLVEG PPGPAGPAGL MGPPGLQGPS GLPGDPGDRG PPGRPGLPGA 480 DGLPGPPGTM LMLPFRYGGD GSKGPTISAQ EAQAQAILQQ ARIALRGPPG PMGLTGRPGP 540 VGGPGSAGAK GESGDPGPQG PRGVQGPPGP TGKPGKRGRP GADGGRGMPG EPGSKGDRGF 600 DGLPGLPGDK GHRGERGPQG PPGLPGDDGM RGEDGEIGPR GLPGEAGPRG LLGPRGTPGP 660 PGQPGIGGID GPQGPKGNMG PQGEPGPPGQ QGNPGPQGLP GPQGPIGPPG EKGPQGKPGL 720 AGLPGADGPP GHPGKEGQSG EKGALGPPGP QGPIGYPGPR GVKGADGVRG LKGSKGEKGE 780 DGFPGFKGDM GLKGDRGEVG QVGPRGEDGP EGPKGRAGPT GDPGPSGQAG EKGKLGVPGL 840 PGYPGRQGPK GSTGFPGFPG ANGEKGARGI AGKPGPRGQR GPTGPRGSRG ARGPTGKPGP 900 KGTSGGDGPP GPPGERGPQG PQGPVGFPGP KGPPGPAGKD GLPGHPGQRG ETGFQGKTGP 960 PGPGGVVGPQ GPTGETGPIG ERGHPGTPGP PGEQGLPGAA GKEGAKGDPG PQGISGKDGP 1020 AGIRGFPGER GLPGAQGAPG LKGGEGPQGP QGPIGSPGER GSAGTAGPIG LPGRPGPQGP 1080 PGPAGEKGAP GEKGPQGPAG RDGVQGPVGL PGPAGPAGSP GEDGDKGEIG EPGQKGSKGD 1140 KGENGPPGPP GLQGPVGAPG IAGGDGEAGP RGQQGMFGQK GDEGARGFPG PPGPIGLQGL 1200 PGPPGEKGEN GDVGPMGPPG PPGPRGPQGP NGADGPQGPP GSIGSVGGVG EKGEPGEAGN 1260 PGPPGEAGSG GPKGERGEKG EAGPPGAAGP PGIKGPPGDD GPKGNPGPVG FPGDPGPPGE 1320 PGPAGQDGVG GDKGEDGDPG QPGPPGPSGE AGPPGPPGKR GPPGASGSEG RQGEKGAKGE 1380 AGAEGPPGKT GPVGPQGPSG KPGPEGLRGI PGPVGEQGLP GAAGQDGPPG PLGPPGLPGL 1440 KGDPGSKGEK GHPGLIGLIG PPGEQGEKGD RGLPGTQGSP GAKGDGGIPG PAGPIGPPGP 1500 PGLPGPAGPK GNKGSSGPTG QKGDSGMPGP PGPPGPPGEV IQPLPILSPK KTRRHTESIQ 1560 ADAGDNILDY SDGMEEIFGS LNSLKQDIEH MKFPMGTQTN PARTCKDLQL SHPDFPDGEY 1620 WIDPNQGCSG DSFKVYCNFT AGGETCIYPD KKSEGVRLSS WPKEKPGSWY SEFKRGKLLS 1680 YLDVEGNSIN MVQMTFLKLL TASARQNFTY NCHQSTAWYD VLSGSYDKAL RFLGSNDEEM 1740 SYENNPHIKA LYDGCASRKG YEKTVIEINT PKIDQVPIID VMINDFGDQN QKFGFEVGPA 1800 CFLG 1804 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL11A1 | 100685969 | J9NYK4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | COL11A1 | A0A452ECM1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL11A1 | 1301 | P12107 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Col11a1 | 12814 | Q61245 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | COL11A1 | A0A2I3RPT1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | COL11A1 | 100349413 | G1T5B6 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Col11a1 | 25654 | P20909 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | col11a1a | 565402 | A2RUX5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005581 | collagen trimer |
| GO:0005592 | collagen type XI trimer |
| GO:0062023 | collagen-containing extracellular matrix |
| GO:0031012 | extracellular matrix |
| GO:0005615 | extracellular space |
| GO:0005201 | extracellular matrix structural constituent |
| GO:1904399 | heparan sulfate binding |
| GO:0008201 | heparin binding |
| GO:0046872 | metal ion binding |
| GO:0001502 | cartilage condensation |
| GO:0051216 | cartilage development |
| GO:0002063 | chondrocyte development |
| GO:0030199 | collagen fibril organization |
| GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0035987 | endodermal cell differentiation |
| GO:0030198 | extracellular matrix organization |
| GO:0003007 | heart morphogenesis |
| GO:0042472 | inner ear morphogenesis |
| GO:0001503 | ossification |
| GO:0006029 | proteoglycan metabolic process |
| GO:0007605 | sensory perception of sound |
| GO:0048705 | skeletal system morphogenesis |
| GO:0035989 | tendon development |
| GO:0055010 | ventricular cardiac muscle tissue morphogenesis |
| GO:0007601 | visual perception |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51461 | NC1_FIB |