Gene Page: FRAT1
Summary ?
| GeneID | 10023 |
| Symbol | FRAT1 |
| Synonyms | - |
| Description | frequently rearranged in advanced T-cell lymphomas 1 |
| Reference | MIM:602503|HGNC:HGNC:3944|Ensembl:ENSG00000165879|HPRD:03935|Vega:OTTHUMG00000018848 |
| Gene type | protein-coding |
| Map location | 10q24.1 |
| Pascal p-value | 0.006 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ATAD2B | 0.97 | 0.93 |
| PBRM1 | 0.97 | 0.96 |
| RFX7 | 0.97 | 0.96 |
| PAK2 | 0.97 | 0.96 |
| ZNF33A | 0.96 | 0.97 |
| CEP170 | 0.96 | 0.96 |
| PPP2R3A | 0.96 | 0.96 |
| ZNF292 | 0.96 | 0.97 |
| ZNF84 | 0.96 | 0.96 |
| ATF7IP | 0.96 | 0.96 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HLA-F | -0.71 | -0.77 |
| AIFM3 | -0.70 | -0.77 |
| AF347015.31 | -0.70 | -0.90 |
| C5orf53 | -0.70 | -0.73 |
| TNFSF12 | -0.69 | -0.68 |
| AF347015.27 | -0.69 | -0.87 |
| PTH1R | -0.69 | -0.75 |
| TSC22D4 | -0.69 | -0.79 |
| MT-CO2 | -0.68 | -0.89 |
| IFI27 | -0.68 | -0.88 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG WNT SIGNALING PATHWAY | 151 | 112 | All SZGR 2.0 genes in this pathway |
| BIOCARTA WNT PATHWAY | 26 | 24 | All SZGR 2.0 genes in this pathway |
| WNT SIGNALING | 89 | 71 | All SZGR 2.0 genes in this pathway |
| ST WNT BETA CATENIN PATHWAY | 34 | 28 | All SZGR 2.0 genes in this pathway |
| PID PS1 PATHWAY | 46 | 39 | All SZGR 2.0 genes in this pathway |
| REACTOME SIGNALING BY WNT | 65 | 41 | All SZGR 2.0 genes in this pathway |
| REACTOME CTNNB1 PHOSPHORYLATION CASCADE | 16 | 11 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE LIVE DN | 384 | 220 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| RASHI RESPONSE TO IONIZING RADIATION 5 | 147 | 89 | All SZGR 2.0 genes in this pathway |
| YANG BREAST CANCER ESR1 LASER UP | 34 | 25 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES WITH H3K27ME3 | 1118 | 744 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| BILD E2F3 ONCOGENIC SIGNATURE | 246 | 153 | All SZGR 2.0 genes in this pathway |
| MITSIADES RESPONSE TO APLIDIN UP | 439 | 257 | All SZGR 2.0 genes in this pathway |
| MARTENS BOUND BY PML RARA FUSION | 456 | 287 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE DN | 841 | 431 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP A | 898 | 516 | All SZGR 2.0 genes in this pathway |