Summary ?
GeneID10087
SymbolCOL4A3BP
SynonymsCERT|CERTL|GPBP|MRD34|STARD11
Descriptioncollagen type IV alpha 3 binding protein
ReferenceMIM:604677|HGNC:HGNC:2205|Ensembl:ENSG00000113163|HPRD:05246|Vega:OTTHUMG00000102068
Gene typeprotein-coding
Map location5q13.3
Pascal p-value0.006
Sherlock p-value0.765

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
RSPH10.900.62
WDR160.890.68
MORN50.890.69
FANK10.890.67
C15orf260.890.51
TCTEX1D10.890.63
C2orf620.890.46
C2orf390.890.54
C3orf250.880.54
RIBC10.880.42
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MEF2C-0.30-0.36
SATB2-0.27-0.34
KLHL1-0.27-0.30
NAV3-0.26-0.30
DACT1-0.25-0.27
ANKRD12-0.25-0.40
MPPED1-0.25-0.31
LRRC7-0.25-0.30
AC073528.1-0.25-0.31
SCUBE1-0.25-0.38

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 3118All SZGR 2.0 genes in this pathway
REACTOME PHOSPHOLIPID METABOLISM 198112All SZGR 2.0 genes in this pathway
REACTOME SPHINGOLIPID METABOLISM 6940All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS 478302All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463290All SZGR 2.0 genes in this pathway
HOOI ST7 TARGETS UP 9457All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404246All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 DN 229142All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 17811082All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER DN 514319All SZGR 2.0 genes in this pathway
FIRESTEIN PROLIFERATION 175125All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO CSF2RB AND IL4 DN 315201All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO HGF UP 418282All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP 408276All SZGR 2.0 genes in this pathway
PANGAS TUMOR SUPPRESSION BY SMAD1 AND SMAD5 DN 157106All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION DN 1080713All SZGR 2.0 genes in this pathway