Summary ?
GeneID10394
SymbolPRG3
SynonymsMBP2|MBPH
Descriptionproteoglycan 3
ReferenceMIM:606814|HGNC:HGNC:9363|Ensembl:ENSG00000156575|HPRD:08434|Vega:OTTHUMG00000167026
Gene typeprotein-coding
Map location11q12
Pascal p-value6.834E-4

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
CNTLN0.780.49
NDC800.760.36
HMGB20.760.53
C20orf720.760.50
TRIP100.760.57
ARHGAP11A0.760.43
DLGAP50.750.34
NUF20.750.41
ACTL6A0.750.52
CEP550.750.36
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
LEPREL2-0.47-0.53
TPST2-0.47-0.54
ACOT4-0.46-0.55
FXYD7-0.46-0.51
NBL1-0.46-0.49
MATK-0.46-0.55
ADAP1-0.46-0.47
RTBDN-0.45-0.58
EPB49-0.45-0.50
TMEM59L-0.45-0.52

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D DN 3119All SZGR 2.0 genes in this pathway
DARWICHE SKIN TUMOR PROMOTER UP 14296All SZGR 2.0 genes in this pathway
DARWICHE PAPILLOMA RISK LOW UP 162104All SZGR 2.0 genes in this pathway
DARWICHE PAPILLOMA RISK HIGH UP 147101All SZGR 2.0 genes in this pathway
DARWICHE SQUAMOUS CELL CARCINOMA UP 146104All SZGR 2.0 genes in this pathway
BYSTROEM CORRELATED WITH IL5 UP 5130All SZGR 2.0 genes in this pathway
ALCALAY AML BY NPM1 LOCALIZATION DN 184132All SZGR 2.0 genes in this pathway
LIAN NEUTROPHIL GRANULE CONSTITUENTS 2513All SZGR 2.0 genes in this pathway
KUMAR TARGETS OF MLL AF9 FUSION 405264All SZGR 2.0 genes in this pathway
CHYLA CBFA2T3 TARGETS UP 387225All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway
NABA PROTEOGLYCANS 3523All SZGR 2.0 genes in this pathway
NABA CORE MATRISOME 275148All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway