Gene Page: PRG3
Summary ?
GeneID | 10394 |
Symbol | PRG3 |
Synonyms | MBP2|MBPH |
Description | proteoglycan 3 |
Reference | MIM:606814|HGNC:HGNC:9363|Ensembl:ENSG00000156575|HPRD:08434|Vega:OTTHUMG00000167026 |
Gene type | protein-coding |
Map location | 11q12 |
Pascal p-value | 6.834E-4 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
CNTLN | 0.78 | 0.49 |
NDC80 | 0.76 | 0.36 |
HMGB2 | 0.76 | 0.53 |
C20orf72 | 0.76 | 0.50 |
TRIP10 | 0.76 | 0.57 |
ARHGAP11A | 0.76 | 0.43 |
DLGAP5 | 0.75 | 0.34 |
NUF2 | 0.75 | 0.41 |
ACTL6A | 0.75 | 0.52 |
CEP55 | 0.75 | 0.36 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
LEPREL2 | -0.47 | -0.53 |
TPST2 | -0.47 | -0.54 |
ACOT4 | -0.46 | -0.55 |
FXYD7 | -0.46 | -0.51 |
NBL1 | -0.46 | -0.49 |
MATK | -0.46 | -0.55 |
ADAP1 | -0.46 | -0.47 |
RTBDN | -0.45 | -0.58 |
EPB49 | -0.45 | -0.50 |
TMEM59L | -0.45 | -0.52 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D DN | 31 | 19 | All SZGR 2.0 genes in this pathway |
DARWICHE SKIN TUMOR PROMOTER UP | 142 | 96 | All SZGR 2.0 genes in this pathway |
DARWICHE PAPILLOMA RISK LOW UP | 162 | 104 | All SZGR 2.0 genes in this pathway |
DARWICHE PAPILLOMA RISK HIGH UP | 147 | 101 | All SZGR 2.0 genes in this pathway |
DARWICHE SQUAMOUS CELL CARCINOMA UP | 146 | 104 | All SZGR 2.0 genes in this pathway |
BYSTROEM CORRELATED WITH IL5 UP | 51 | 30 | All SZGR 2.0 genes in this pathway |
ALCALAY AML BY NPM1 LOCALIZATION DN | 184 | 132 | All SZGR 2.0 genes in this pathway |
LIAN NEUTROPHIL GRANULE CONSTITUENTS | 25 | 13 | All SZGR 2.0 genes in this pathway |
KUMAR TARGETS OF MLL AF9 FUSION | 405 | 264 | All SZGR 2.0 genes in this pathway |
CHYLA CBFA2T3 TARGETS UP | 387 | 225 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |
NABA PROTEOGLYCANS | 35 | 23 | All SZGR 2.0 genes in this pathway |
NABA CORE MATRISOME | 275 | 148 | All SZGR 2.0 genes in this pathway |
NABA MATRISOME | 1028 | 559 | All SZGR 2.0 genes in this pathway |