Gene Page: SLC22A7

Summary
GeneID  10864
Symbol  SLC22A7
Synonyms  MGC24091|MGC45202|NLT|OAT2
Description  solute carrier family 22 (organic anion transporter), member 7
See related  HGNC:10971|MIM:604995|Ensembl:ENSG00000137204|HPRD:05409|
Locus tag  RP11-480N24.7
Gene type  protein-coding
Map location  6p21.2-p21.1
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.04433 
ExpressionExpressionP value: 1.577 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
ABCF20.910.91
NPEPPS0.910.90
RABGEF10.910.91
CS0.910.91
XPO70.910.92
ZFYVE10.910.92
PDXDC10.910.91
NNT0.910.90
ADD10.910.92
POLR3A0.910.93
Top 10 negatively co-expressed genes
AF347015.21-0.80-0.87
MT-CO2-0.80-0.82
AF347015.31-0.80-0.82
AF347015.8-0.78-0.81
AF347015.27-0.77-0.81
MT-CYB-0.77-0.79
AF347015.33-0.77-0.78
HIGD1B-0.76-0.80
IFI27-0.75-0.79
FXYD1-0.75-0.80
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005215transporter activityIEA-
GO:0008514organic anion transmembrane transporter activityIEA-
GO:0015347sodium-independent organic anion transmembrane transporter activityTAS9650585 
GO:0015075ion transmembrane transporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0015711organic anion transportTAS9650585 
GO:0006811ion transportIEA-
GO:0006810transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionTAS9650585 
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS9650585 
GO:0016323basolateral plasma membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 241157All SZGR genes in this pathway
REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 8954All SZGR genes in this pathway
REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT 139All SZGR genes in this pathway
JAZAG_TGFB1_SIGNALING_UP 10869All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 261153All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_DN 267160All SZGR genes in this pathway
OHGUCHI_LIVER_HNF4A_TARGETS_DN 14985All SZGR genes in this pathway
SERVITJA_LIVER_HNF1A_TARGETS_DN 157105All SZGR genes in this pathway
GUILLAUMOND_KLF10_TARGETS_UP 5139All SZGR genes in this pathway


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