Gene Page: LECT1
Summary ?
| GeneID | 11061 |
| Symbol | LECT1 |
| Synonyms | BRICD3|CHM-I|CHM1|MYETS1 |
| Description | leukocyte cell derived chemotaxin 1 |
| Reference | MIM:605147|HGNC:HGNC:17005|Ensembl:ENSG00000136110|HPRD:05511|Vega:OTTHUMG00000016980 |
| Gene type | protein-coding |
| Map location | 13q14.3 |
| Pascal p-value | 0.001 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs16869851 | chr4 | 20690056 | LECT1 | 11061 | 0.16 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| NDE1 | 0.77 | 0.68 |
| CREB5 | 0.75 | 0.68 |
| CDC25B | 0.74 | 0.75 |
| PSRC1 | 0.74 | 0.80 |
| E2F1 | 0.71 | 0.72 |
| CYTSB | 0.71 | 0.77 |
| SALL1 | 0.71 | 0.65 |
| CRTAP | 0.70 | 0.67 |
| SNX1 | 0.70 | 0.74 |
| CHD1L | 0.69 | 0.73 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| KRT19 | -0.32 | -0.34 |
| RP9P | -0.32 | -0.41 |
| C3orf54 | -0.31 | -0.24 |
| KLHL1 | -0.31 | -0.10 |
| TRIM67 | -0.30 | -0.14 |
| SATB2 | -0.29 | -0.02 |
| IL32 | -0.29 | -0.22 |
| DACT1 | -0.28 | -0.11 |
| FBLIM1 | -0.28 | -0.22 |
| AC087071.1 | -0.28 | -0.29 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ROVERSI GLIOMA COPY NUMBER UP | 100 | 75 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS NEUROEPITHELIUM DN | 164 | 111 | All SZGR 2.0 genes in this pathway |
| SHETH LIVER CANCER VS TXNIP LOSS PAM4 | 261 | 153 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES 1 | 379 | 235 | All SZGR 2.0 genes in this pathway |
| BENPORATH NANOG TARGETS | 988 | 594 | All SZGR 2.0 genes in this pathway |
| STAEGE EWING FAMILY TUMOR | 33 | 22 | All SZGR 2.0 genes in this pathway |
| MOREAUX MULTIPLE MYELOMA BY TACI UP | 412 | 249 | All SZGR 2.0 genes in this pathway |
| VART KSHV INFECTION ANGIOGENIC MARKERS DN | 138 | 92 | All SZGR 2.0 genes in this pathway |
| COLINA TARGETS OF 4EBP1 AND 4EBP2 | 356 | 214 | All SZGR 2.0 genes in this pathway |
| CHEN METABOLIC SYNDROM NETWORK | 1210 | 725 | All SZGR 2.0 genes in this pathway |
| MEISSNER ES ICP WITH H3K4ME3 AND H3K27ME3 | 14 | 8 | All SZGR 2.0 genes in this pathway |
| MEISSNER NPC ICP WITH H3 UNMETHYLATED | 24 | 15 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN IPS ICP WITH H3K4ME3 AND H327ME3 | 126 | 83 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 AND H3K27ME3 | 137 | 85 | All SZGR 2.0 genes in this pathway |
| NOUSHMEHR GBM SILENCED BY METHYLATION | 50 | 32 | All SZGR 2.0 genes in this pathway |