Gene Page: RCAN3
Summary ?
| GeneID | 11123 |
| Symbol | RCAN3 |
| Synonyms | DSCR1L2|MCIP3|RCN3|hRCN3 |
| Description | RCAN family member 3 |
| Reference | MIM:605860|HGNC:HGNC:3042|Ensembl:ENSG00000117602|HPRD:05792| |
| Gene type | protein-coding |
| Map location | 1p36.11 |
| Pascal p-value | 0.005 |
| eGene | Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| NCAPH2 | 0.83 | 0.82 |
| TRMT2A | 0.82 | 0.83 |
| NPDC1 | 0.82 | 0.83 |
| TRMT1 | 0.82 | 0.81 |
| COQ4 | 0.82 | 0.84 |
| DMAP1 | 0.82 | 0.81 |
| SDR39U1 | 0.81 | 0.81 |
| RNF25 | 0.81 | 0.82 |
| TTLL3 | 0.81 | 0.80 |
| OVCA2 | 0.81 | 0.81 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.8 | -0.66 | -0.60 |
| AF347015.27 | -0.66 | -0.61 |
| MT-CYB | -0.65 | -0.59 |
| MT-CO2 | -0.64 | -0.57 |
| AF347015.15 | -0.64 | -0.58 |
| AF347015.31 | -0.64 | -0.58 |
| AF347015.2 | -0.64 | -0.59 |
| AF347015.33 | -0.64 | -0.59 |
| MT-ATP8 | -0.62 | -0.65 |
| AF347015.21 | -0.61 | -0.60 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| HUTTMANN B CLL POOR SURVIVAL UP | 276 | 187 | All SZGR 2.0 genes in this pathway |
| SABATES COLORECTAL ADENOMA SIZE DN | 14 | 8 | All SZGR 2.0 genes in this pathway |
| JAATINEN HEMATOPOIETIC STEM CELL DN | 226 | 132 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN | 805 | 505 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC DN | 537 | 339 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP | 552 | 347 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| NUYTTEN NIPP1 TARGETS DN | 848 | 527 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS UP | 811 | 508 | All SZGR 2.0 genes in this pathway |
| LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
| WONG ADULT TISSUE STEM MODULE | 721 | 492 | All SZGR 2.0 genes in this pathway |
| WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP | 397 | 206 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE LATE | 1137 | 655 | All SZGR 2.0 genes in this pathway |
| ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF | 516 | 308 | All SZGR 2.0 genes in this pathway |