Gene Page: CKB

Summary
GeneID  1152
Symbol  CKB
Synonyms  B-CK|CKBB
Description  creatine kinase, brain
See related  HGNC:1991|MIM:123280|Ensembl:ENSG00000166165|HPRD:00423|
Locus tag  -
Gene type  protein-coding
Map location  14q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MYNN0.940.93
KLHL70.930.91
COPB10.930.93
ZNF4840.920.89
DCAF130.920.89
SNX40.920.89
HSF20.920.91
ZNF5690.910.90
GNAI30.910.83
MCPH10.910.90
Top 10 negatively co-expressed genes
AF347015.27-0.68-0.83
HLA-F-0.68-0.79
MT-CO2-0.68-0.84
AF347015.33-0.67-0.83
MT-CYB-0.67-0.84
AF347015.8-0.67-0.85
AF347015.31-0.66-0.82
AF347015.15-0.66-0.85
AIFM3-0.64-0.75
TINAGL1-0.64-0.75
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0004111creatine kinase activityTAS3034271 
GO:0005524ATP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006600creatine metabolic processEXP10893433 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005829cytosolEXP16981706 
GO:0005737cytoplasmIEA-
GO:0005739mitochondrionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ASB9DKFZp564L0862 | FLJ20636 | MGC4954ankyrin repeat and SOCS box-containing 9Two-hybridBioGRID16189514 
CKMCKMM | M-CKcreatine kinase, muscle-HPRD,BioGRID9748661 
SERP2C13orf21 | MGC35505 | RP11-269C23.1 | bA269C23.1stress-associated endoplasmic reticulum protein family member 2Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ARGININE_AND_PROLINE_METABOLISM 5439All SZGR genes in this pathway
REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 200136All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN 349157All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN 493298All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
DOANE_RESPONSE_TO_ANDROGEN_DN 241146All SZGR genes in this pathway
BASAKI_YBX1_TARGETS_DN 384230All SZGR genes in this pathway
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP 158103All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP 194122All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_1_DN 242165All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_DN 281186All SZGR genes in this pathway
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP 204140All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
PROVENZANI_METASTASIS_DN 13694All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_DN 508354All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_UP 530342All SZGR genes in this pathway
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_DN 1917All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
PEREZ_TP63_TARGETS 355243All SZGR genes in this pathway
PEREZ_TP53_AND_TP63_TARGETS 205145All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_DN 193112All SZGR genes in this pathway
WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP 7347All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_DN 9859All SZGR genes in this pathway
LOPEZ_MBD_TARGETS 957597All SZGR genes in this pathway
GOUYER_TUMOR_INVASIVENESS 95All SZGR genes in this pathway
SUNG_METASTASIS_STROMA_UP 11070All SZGR genes in this pathway
PENG_LEUCINE_DEPRIVATION_UP 14293All SZGR genes in this pathway
NADLER_OBESITY_UP 6134All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_DN 10267All SZGR genes in this pathway
CROMER_METASTASIS_DN 8158All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_NEOCORTEX_UP 8366All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
APRELIKOVA_BRCA1_TARGETS 4933All SZGR genes in this pathway
YAMAZAKI_TCEB3_TARGETS_DN 215132All SZGR genes in this pathway
PAL_PRMT5_TARGETS_DN 2916All SZGR genes in this pathway
LEE_AGING_NEOCORTEX_UP 8959All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
DURCHDEWALD_SKIN_CARCINOGENESIS_UP 8847All SZGR genes in this pathway
STEIN_ESRRA_TARGETS_UP 388234All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
BLUM_RESPONSE_TO_SALIRASIB_DN 342220All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_DN 5939All SZGR genes in this pathway
CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP 5132All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_DN 5230All SZGR genes in this pathway
STEIN_ESRRA_TARGETS 535325All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_PCA3_UP 8054All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_UP 207143All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 181101All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_ALL_DISORDERS_DURATION_CORR_DN 14690All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_4_DN 1611All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
YANG_BCL3_TARGETS_UP 364236All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
DELACROIX_RAR_TARGETS_DN 2416All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1391071131Ahsa-miR-139brainUCUACAGUGCACGUGUCU
miR-324-3p5258m8hsa-miR-324-3pCCACUGCCCCAGGUGCUGCUGG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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