SZGR2

Summary ?

GeneID	1959
Symbol	EGR2
Synonyms	AT591\|CMT1D\|CMT4E\|KROX20
Description	early growth response 2
Reference	MIM:129010\|HGNC:HGNC:3239\|Ensembl:ENSG00000122877\|HPRD:00551\|Vega:OTTHUMG00000018308
Gene type	protein-coding
Map location	10q21.1
Pascal p-value	0.061
Fetal beta	-1.595
eGene	Myers' cis & trans

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias	Click to show details
GO_Annotation	Mapping neuro-related keywords to Gene Ontology annotations	Hits with neuro-related keywords: 1

Section I. Genetics and epigenetics annotation

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	qvalue	eQTL type
rs16918799	chr10	65464025	EGR2	1959	0.14	cis
rs307378		0	EGR2	1959	0.19	trans
rs6677917	chr1	34406841	EGR2	1959	0.14	trans
rs983619	chr1	39047418	EGR2	1959	0.05	trans
rs7545984	chr1	45003892	EGR2	1959	0.01	trans
rs7554123	chr1	45004203	EGR2	1959	0.01	trans
rs12059674	chr1	57630277	EGR2	1959	0.02	trans
rs17126801	chr1	65098162	EGR2	1959	0.02	trans
rs17474410	chr1	68267242	EGR2	1959	0.14	trans
rs7511937		0	EGR2	1959	0	trans
rs2782784	chr1	71195282	EGR2	1959	0.01	trans
rs2257700	chr1	71273516	EGR2	1959	0.05	trans
rs7541092	chr1	71362471	EGR2	1959	0.09	trans
rs17689089	chr1	77740105	EGR2	1959	0	trans
rs17100231	chr1	77761339	EGR2	1959	0.01	trans
rs17100274	chr1	77774412	EGR2	1959	3.806E-5	trans
rs12034005	chr1	79793034	EGR2	1959	0.04	trans
rs3015033	chr1	79847235	EGR2	1959	0.01	trans
rs17098656	chr1	80098386	EGR2	1959	0.01	trans
rs6664544	chr1	92524192	EGR2	1959	0	trans
rs12403481	chr1	109503655	EGR2	1959	0	trans
rs337294		0	EGR2	1959	0.02	trans
rs17029293	chr1	112567844	EGR2	1959	2.975E-4	trans
rs16837984	chr1	157042626	EGR2	1959	0	trans
rs16837989	chr1	157046286	EGR2	1959	0.01	trans
rs16838012	chr1	157048974	EGR2	1959	0	trans
rs16838014		0	EGR2	1959	0	trans
rs4657385	chr1	164939279	EGR2	1959	0.14	trans
rs6666937	chr1	170286842	EGR2	1959	8.539E-4	trans
rs12071422	chr1	185573879	EGR2	1959	0.01	trans
rs16843112	chr1	198420657	EGR2	1959	0.19	trans
rs697455	chr1	202512075	EGR2	1959	0.02	trans
rs4457633	chr1	204283819	EGR2	1959	0.04	trans
rs3748669	chr1	207077022	EGR2	1959	0.01	trans
rs6673109	chr1	207253132	EGR2	1959	9.237E-5	trans
rs17260245	chr1	209411024	EGR2	1959	0.17	trans
rs1796829	chr1	239661818	EGR2	1959	3.155E-4	trans
rs12034521	chr1	239717679	EGR2	1959	1.996E-5	trans
rs6670526	chr1	239725414	EGR2	1959	0.16	trans
snp_a-1990354		0	EGR2	1959	9.225E-7	trans
rs939217	chr2	12730751	EGR2	1959	0.03	trans
rs6432434	chr2	14160930	EGR2	1959	0	trans
rs6712107	chr2	14178653	EGR2	1959	0.03	trans
rs16861129	chr2	14201738	EGR2	1959	0.03	trans
rs16861131	chr2	14202085	EGR2	1959	0.03	trans
rs7589712	chr2	14205064	EGR2	1959	0.14	trans
rs12329305	chr2	19552912	EGR2	1959	0	trans
rs12611832	chr2	31196248	EGR2	1959	0.02	trans
rs12614732	chr2	31199913	EGR2	1959	0.02	trans
rs17023938	chr2	39773236	EGR2	1959	0.18	trans
rs7560081	chr2	62793238	EGR2	1959	0	trans
rs17029079	chr2	64736071	EGR2	1959	0.01	trans
rs17038084	chr2	85192280	EGR2	1959	4.202E-5	trans
rs17024035	chr2	100968559	EGR2	1959	0.06	trans
rs7574684	chr2	100992911	EGR2	1959	0.06	trans
rs17024129	chr2	100995144	EGR2	1959	0.06	trans
rs7585898	chr2	100998292	EGR2	1959	0.06	trans
rs1370627	chr2	101009384	EGR2	1959	0.06	trans
rs17042517	chr2	113639583	EGR2	1959	0.18	trans
rs17047906	chr2	119007824	EGR2	1959	0.12	trans
rs1840209	chr2	125625401	EGR2	1959	0.02	trans
rs6707117	chr2	136855504	EGR2	1959	2.06E-12	trans
rs17834293	chr2	142993878	EGR2	1959	0.14	trans
rs7564795	chr2	143033291	EGR2	1959	0.09	trans
rs10189091	chr2	143471999	EGR2	1959	9.547E-4	trans
snp_a-2198363		0	EGR2	1959	0.01	trans
rs707097	chr2	155318814	EGR2	1959	0.03	trans
rs16838911	chr2	156087569	EGR2	1959	3.899E-4	trans
rs12469388	chr2	178689030	EGR2	1959	0.19	trans
rs7608942	chr2	182820100	EGR2	1959	0.03	trans
rs16848675	chr2	213349996	EGR2	1959	0.04	trans
rs16829292	chr2	233447622	EGR2	1959	0.01	trans
rs16829401	chr2	233538391	EGR2	1959	0	trans
rs17040622	chr3	4440673	EGR2	1959	0.01	trans
rs17684934	chr3	4443547	EGR2	1959	1.114E-4	trans
rs17040633	chr3	4446836	EGR2	1959	1.114E-4	trans
rs17756483	chr3	4451309	EGR2	1959	1.114E-4	trans
rs17685441	chr3	4465165	EGR2	1959	1.114E-4	trans
rs17015415	chr3	24933888	EGR2	1959	0.03	trans
rs12639503	chr3	51860816	EGR2	1959	0.06	trans
rs9863778	chr3	55375950	EGR2	1959	0.02	trans
rs997245	chr3	61844600	EGR2	1959	8.765E-4	trans
rs3796213	chr3	69157380	EGR2	1959	0.05	trans
rs6549186	chr3	69211954	EGR2	1959	0.07	trans
rs2875492	chr3	86006209	EGR2	1959	0.01	trans
rs16843128	chr3	100713413	EGR2	1959	6.137E-4	trans
rs1381835	chr3	110600595	EGR2	1959	0	trans
rs1877965	chr3	126013904	EGR2	1959	0.15	trans
rs9289277	chr3	126038339	EGR2	1959	0.1	trans
rs16839796	chr4	7188348	EGR2	1959	7.519E-5	trans
rs4631023	chr4	8101794	EGR2	1959	0.07	trans
rs7684087	chr4	21673380	EGR2	1959	0.01	trans
rs16989064	chr4	33639397	EGR2	1959	0	trans
rs11096966	chr4	38961258	EGR2	1959	0.13	trans
rs4469113	chr4	41461062	EGR2	1959	2.509E-4	trans
rs6836259	chr4	57173074	EGR2	1959	0.06	trans
rs2643038	chr4	62313218	EGR2	1959	0.01	trans
snp_a-1830437		0	EGR2	1959	0.15	trans
rs6817626	chr4	78005836	EGR2	1959	0.04	trans
rs1604153	chr4	78472744	EGR2	1959	0.02	trans
rs1564462	chr4	79910988	EGR2	1959	0.08	trans
rs6827713	chr4	79936877	EGR2	1959	0.02	trans
rs17005000	chr4	81826551	EGR2	1959	0.04	trans
rs10011751	chr4	93984994	EGR2	1959	0.01	trans
rs11099888	chr4	154498555	EGR2	1959	0.07	trans
rs17701328	chr4	178744532	EGR2	1959	0.17	trans
rs6881821	chr5	8578465	EGR2	1959	8.795E-5	trans
rs9312843	chr5	13802997	EGR2	1959	0	trans
rs1732944	chr5	30905595	EGR2	1959	0.11	trans
rs1697073	chr5	30907267	EGR2	1959	0.01	trans
rs9292700	chr5	38192610	EGR2	1959	0.18	trans
rs2115110	chr5	38193428	EGR2	1959	1.764E-5	trans
rs16873956	chr5	44312488	EGR2	1959	0	trans
rs10040715	chr5	57594207	EGR2	1959	5.105E-11	trans
rs16894149	chr5	61013724	EGR2	1959	0.1	trans
snp_a-4217300		0	EGR2	1959	1.213E-6	trans
rs1862599	chr5	82095088	EGR2	1959	0	trans
rs163953	chr5	92289536	EGR2	1959	0.01	trans
rs17134275	chr5	100634998	EGR2	1959	0	trans
rs17257221	chr5	101016609	EGR2	1959	0.07	trans
rs10063272	chr5	103540974	EGR2	1959	0.1	trans
rs2963232	chr5	103713882	EGR2	1959	0.02	trans
rs250323	chr5	115646995	EGR2	1959	0.03	trans
rs1350578	chr5	116310282	EGR2	1959	0.02	trans
rs2900115	chr5	117414349	EGR2	1959	0.11	trans
rs11955842	chr5	118066618	EGR2	1959	0.04	trans
rs6894229	chr5	127160990	EGR2	1959	0.18	trans
rs2141482	chr5	136760477	EGR2	1959	8.057E-5	trans
snp_a-1983671		0	EGR2	1959	0.18	trans
rs2189803	chr5	137684661	EGR2	1959	1.274E-8	trans
rs17063216	chr5	163777647	EGR2	1959	0.02	trans
rs17063224	chr5	163780687	EGR2	1959	0.02	trans
rs17666252	chr5	168294345	EGR2	1959	0.19	trans
snp_a-2055204		0	EGR2	1959	0.04	trans
rs259913	chr5	169370782	EGR2	1959	1.629E-5	trans
snp_a-2275210		0	EGR2	1959	0.17	trans
rs2116811	chr5	171820051	EGR2	1959	3.122E-4	trans
rs258875	chr5	173046554	EGR2	1959	0.05	trans
rs16883859	chr6	20474617	EGR2	1959	0.09	trans
rs16883862	chr6	20474766	EGR2	1959	0.09	trans
rs10484635	chr6	20538664	EGR2	1959	0.05	trans
rs7747254	chr6	24013530	EGR2	1959	0.14	trans
rs3909134	chr6	29699252	EGR2	1959	0.13	trans
rs195429	chr6	37354434	EGR2	1959	0.01	trans
rs16890522	chr6	38236301	EGR2	1959	0.16	trans
rs12528414	chr6	38404800	EGR2	1959	0.03	trans
rs7764900	chr6	38440495	EGR2	1959	0.08	trans
rs6915776	chr6	71797961	EGR2	1959	0.19	trans
rs17069168	chr6	108335432	EGR2	1959	0.11	trans
rs17069171	chr6	108335593	EGR2	1959	0.05	trans
rs391196	chr6	111563907	EGR2	1959	0.06	trans
rs4289676	chr6	123999302	EGR2	1959	7.47E-4	trans
rs17055235	chr6	128355263	EGR2	1959	0.06	trans
rs2030024	chr6	131014624	EGR2	1959	0	trans
rs9402280	chr6	131102770	EGR2	1959	0.01	trans
rs17062925	chr6	134168614	EGR2	1959	0.18	trans
rs7767456	chr6	134356119	EGR2	1959	0.03	trans
rs9385758	chr6	136729593	EGR2	1959	0.19	trans
rs12176346	chr6	136732663	EGR2	1959	0	trans
rs9402819	chr6	136848169	EGR2	1959	0.02	trans
rs9389400	chr6	136854803	EGR2	1959	0.02	trans
rs2237264	chr6	136919977	EGR2	1959	0	trans
rs17080121	chr6	151009189	EGR2	1959	0	trans
rs12529269	chr6	153543829	EGR2	1959	0	trans
rs10872699	chr6	153544252	EGR2	1959	4.044E-5	trans
rs1321606	chr6	153545278	EGR2	1959	0	trans
rs10945911	chr6	164047509	EGR2	1959	1.075E-4	trans
rs17156078	chr7	27988688	EGR2	1959	0	trans
rs12701006	chr7	30147298	EGR2	1959	1.07E-6	trans
rs1156490	chr7	34334956	EGR2	1959	0.17	trans
rs1419793	chr7	34697630	EGR2	1959	0.19	trans
rs17815964	chr7	52540908	EGR2	1959	0.04	trans
rs17621151	chr7	53572911	EGR2	1959	1.204E-4	trans
rs10245449	chr7	80935100	EGR2	1959	0.01	trans
rs2272618	chr7	107871360	EGR2	1959	0.13	trans
rs12669568	chr7	107885942	EGR2	1959	0.13	trans
rs7777322	chr7	107886663	EGR2	1959	0.13	trans
rs12671672	chr7	117614219	EGR2	1959	0.03	trans
rs10487383	chr7	117671737	EGR2	1959	0	trans
rs6958821	chr7	153253566	EGR2	1959	0	trans
rs1865462	chr7	157637961	EGR2	1959	0.12	trans
rs11779237	chr8	1227664	EGR2	1959	0.01	trans
rs1358128	chr8	5268072	EGR2	1959	0.01	trans
rs12682256	chr8	5306138	EGR2	1959	0.01	trans
rs1010895	chr8	14580230	EGR2	1959	0.02	trans
rs10109456	chr8	19565941	EGR2	1959	0.01	trans
rs17054681	chr8	25814323	EGR2	1959	0.07	trans
rs16877914	chr8	31196384	EGR2	1959	0.08	trans
rs1457044	chr8	59257567	EGR2	1959	4.062E-7	trans
rs1457032	chr8	59290536	EGR2	1959	4.955E-5	trans
rs2680903	chr8	59512333	EGR2	1959	0.04	trans
rs2634533	chr8	59535621	EGR2	1959	0.06	trans
rs7465259		0	EGR2	1959	0.01	trans
rs10104622	chr8	63333773	EGR2	1959	0.01	trans
rs2218911	chr8	63371015	EGR2	1959	0.01	trans
rs1551199	chr8	63388117	EGR2	1959	0.01	trans
rs1733950	chr8	90062516	EGR2	1959	2.51E-10	trans
rs1240028	chr8	90093357	EGR2	1959	1.261E-4	trans
rs1240087	chr8	90113945	EGR2	1959	5.906E-4	trans
rs318307	chr8	90185459	EGR2	1959	1.775E-4	trans
rs1483373	chr8	90186442	EGR2	1959	0.02	trans
rs11776005	chr8	90187416	EGR2	1959	0	trans
rs1159499	chr8	90196948	EGR2	1959	0.01	trans
rs1355060	chr8	118717710	EGR2	1959	0	trans
rs2280828	chr8	118762435	EGR2	1959	0	trans
rs17683401	chr8	119671834	EGR2	1959	0.16	trans
rs16901935	chr8	128076544	EGR2	1959	0.07	trans
rs4976941	chr8	142744439	EGR2	1959	3.33E-5	trans
rs9298651	chr9	10076275	EGR2	1959	1.259E-5	trans
rs16931013	chr9	10076859	EGR2	1959	1.259E-5	trans
rs1467547	chr9	17630726	EGR2	1959	0.01	trans
rs4415417	chr9	17837857	EGR2	1959	0.06	trans
rs2210327	chr9	18109234	EGR2	1959	0.03	trans
rs6476383	chr9	32865568	EGR2	1959	0.02	trans
rs11143622	chr9	71370050	EGR2	1959	0.01	trans
rs11143868	chr9	71437411	EGR2	1959	0.06	trans
rs11143995	chr9	71462852	EGR2	1959	0.06	trans
rs11144031	chr9	71477107	EGR2	1959	0.06	trans
rs11791891	chr9	87512411	EGR2	1959	0.01	trans
rs2165893	chr9	87531423	EGR2	1959	0	trans
rs763623	chr9	87539663	EGR2	1959	0.12	trans
rs3780642	chr9	87553144	EGR2	1959	6.457E-6	trans
rs10992752	chr9	96240578	EGR2	1959	0.01	trans
rs10981864	chr9	116416735	EGR2	1959	0.1	trans
snp_a-1879318		0	EGR2	1959	0.09	trans
rs2807706	chr9	121744331	EGR2	1959	2.853E-4	trans
rs2818297	chr9	121757015	EGR2	1959	0.01	trans
rs10739527	chr9	121772512	EGR2	1959	0.01	trans
rs6537944	chr9	137312827	EGR2	1959	0.02	trans
rs11103132	chr9	138575901	EGR2	1959	0.01	trans
rs1017361	chr10	294952	EGR2	1959	0.16	trans
rs6560840	chr10	489655	EGR2	1959	0.03	trans
rs11252514	chr10	499572	EGR2	1959	8.532E-4	trans
rs2924269	chr10	4884783	EGR2	1959	0.13	trans
rs11014370	chr10	25352798	EGR2	1959	0.02	trans
rs772394	chr10	35980024	EGR2	1959	0	trans
rs17432714	chr10	43526022	EGR2	1959	0.05	trans
rs2853836	chr10	48431948	EGR2	1959	0.02	trans
rs1908351	chr10	57877117	EGR2	1959	0	trans
rs3104871	chr10	57878502	EGR2	1959	7.348E-5	trans
rs901309	chr10	72571899	EGR2	1959	0.01	trans
rs4750827	chr10	132547183	EGR2	1959	0.03	trans
rs4750829	chr10	132547260	EGR2	1959	0.04	trans
rs11021918	chr11	2269189	EGR2	1959	0.01	trans
rs862785	chr11	20175604	EGR2	1959	0.02	trans
rs16911034	chr11	23302320	EGR2	1959	0	trans
rs10838551	chr11	46073112	EGR2	1959	0.09	trans
rs10838567	chr11	46136342	EGR2	1959	0.09	trans
rs12292520	chr11	48086150	EGR2	1959	0.07	trans
rs17142688	chr11	81319064	EGR2	1959	0.07	trans
rs619320	chr11	81846219	EGR2	1959	0.13	trans
rs11020043	chr11	92470587	EGR2	1959	0.06	trans
rs2460047	chr11	93678935	EGR2	1959	0.18	trans
rs1789300	chr11	95463631	EGR2	1959	4.92E-4	trans
rs1727152	chr11	95467435	EGR2	1959	0.02	trans
rs1255149	chr11	95484493	EGR2	1959	4.64E-4	trans
rs3748251	chr11	95519156	EGR2	1959	1.302E-4	trans
rs16922543	chr11	95526116	EGR2	1959	1.302E-4	trans
rs16922622	chr11	95567387	EGR2	1959	1.302E-4	trans
rs3181323	chr11	104878386	EGR2	1959	0.01	trans
rs11219092	chr11	123130750	EGR2	1959	0.05	trans
rs7119608	chr11	134922824	EGR2	1959	0.08	trans
rs766095	chr12	1498432	EGR2	1959	0.15	trans
rs2109556	chr12	3887300	EGR2	1959	0.14	trans
rs733593	chr12	6636391	EGR2	1959	0.01	trans
rs2058798	chr12	16743164	EGR2	1959	0.12	trans
rs374484	chr12	27627159	EGR2	1959	8.488E-4	trans
rs451921	chr12	27627499	EGR2	1959	0.11	trans
rs10771436	chr12	28744556	EGR2	1959	0.06	trans
rs1344796	chr12	76397104	EGR2	1959	3.074E-4	trans
rs11831213	chr12	109895355	EGR2	1959	0.11	trans
rs10850201	chr12	109903061	EGR2	1959	0	trans
rs7133714	chr12	120141546	EGR2	1959	0.08	trans
rs11833075	chr12	122114592	EGR2	1959	9.326E-5	trans
rs1041050	chr13	26585121	EGR2	1959	0.01	trans
rs9581602	chr13	26834548	EGR2	1959	0.03	trans
rs17084271	chr13	27089799	EGR2	1959	0.03	trans
rs17084280	chr13	27090872	EGR2	1959	0.03	trans
rs9569893	chr13	34198563	EGR2	1959	0.09	trans
rs2408301	chr13	51808915	EGR2	1959	0.08	trans
rs7982110	chr13	59723428	EGR2	1959	6.427E-4	trans
rs9528250	chr13	61410190	EGR2	1959	0	trans
rs7330331	chr13	67403122	EGR2	1959	5.763E-4	trans
rs17088392	chr13	72257235	EGR2	1959	0.04	trans
rs7327697	chr13	83227456	EGR2	1959	7.968E-5	trans
rs17667894	chr13	92014308	EGR2	1959	0	trans
rs223110	chr14	23973042	EGR2	1959	0.08	trans
rs7156088	chr14	27821865	EGR2	1959	6.427E-4	trans
rs8013705	chr14	34853284	EGR2	1959	0.08	trans
rs17106703	chr14	37851979	EGR2	1959	0.16	trans
rs7147321	chr14	45877904	EGR2	1959	0.01	trans
rs1952728	chr14	45893091	EGR2	1959	0.01	trans
rs17116137	chr14	45940865	EGR2	1959	0.01	trans
rs7151829	chr14	45971281	EGR2	1959	0.01	trans
rs8022005	chr14	61345380	EGR2	1959	0	trans
rs17100844	chr14	63669261	EGR2	1959	0.12	trans
rs10148418	chr14	67003872	EGR2	1959	0	trans
rs149642	chr14	72653498	EGR2	1959	0.02	trans
rs3861624	chr14	78416193	EGR2	1959	0.07	trans
rs941539	chr14	93561214	EGR2	1959	0.05	trans
rs1885073	chr14	104357181	EGR2	1959	3.959E-6	trans
rs4465541	chr14	105016846	EGR2	1959	0.09	trans
rs16973929	chr15	47395709	EGR2	1959	0.01	trans
rs8039808	chr15	49939845	EGR2	1959	0.09	trans
rs10518936	chr15	58090522	EGR2	1959	0.04	trans
rs2414703	chr15	61904602	EGR2	1959	0.01	trans
rs289171	chr15	62576053	EGR2	1959	5.831E-4	trans
rs289161	chr15	62589888	EGR2	1959	9.705E-4	trans
rs939043	chr15	70236428	EGR2	1959	0.19	trans
rs11858762	chr15	81386594	EGR2	1959	0.03	trans
rs9635390	chr15	90809632	EGR2	1959	2.566E-5	trans
rs7174562	chr15	93811530	EGR2	1959	0.07	trans
rs16948359	chr15	94233206	EGR2	1959	0.19	trans
rs16948375	chr15	94236354	EGR2	1959	0.03	trans
rs17140355	chr16	6548831	EGR2	1959	0.12	trans
rs8047151	chr16	17209696	EGR2	1959	1.871E-7	trans
rs4271578	chr16	17213886	EGR2	1959	4.061E-6	trans
rs7200513	chr16	17219474	EGR2	1959	0.01	trans
rs3829495	chr16	17221986	EGR2	1959	5.763E-4	trans
rs7193763	chr16	17225534	EGR2	1959	5.351E-5	trans
rs11861635	chr16	82543377	EGR2	1959	0.03	trans
rs276966	chr16	86233753	EGR2	1959	0.03	trans
rs643099	chr17	6568815	EGR2	1959	0.19	trans
rs1867231	chr17	13678834	EGR2	1959	0.06	trans
rs9903086	chr17	39949515	EGR2	1959	0.16	trans
rs7219986	chr17	53263206	EGR2	1959	0	trans
rs17817797	chr17	53332496	EGR2	1959	9.358E-4	trans
rs16951770	chr18	7444826	EGR2	1959	0.01	trans
rs2851752	chr18	25350684	EGR2	1959	0.11	trans
rs7244394	chr18	32223105	EGR2	1959	0.02	trans
snp_a-4248697		0	EGR2	1959	0.02	trans
rs16951384	chr18	47527116	EGR2	1959	0.08	trans
rs10502924	chr18	49172178	EGR2	1959	0.12	trans
rs17064695	chr18	55956427	EGR2	1959	0.05	trans
rs1469489	chr18	57228488	EGR2	1959	0.15	trans
rs1469490	chr18	57229886	EGR2	1959	0.11	trans
rs17074993	chr18	63260128	EGR2	1959	0.01	trans
snp_a-1821751		0	EGR2	1959	0	trans
rs1942461	chr18	70509159	EGR2	1959	0.01	trans
rs1942462	chr18	70509823	EGR2	1959	0.01	trans
rs1942463	chr18	70509841	EGR2	1959	0.01	trans
rs1942464	chr18	70509877	EGR2	1959	2.489E-4	trans
rs1942466	chr18	70517154	EGR2	1959	0.01	trans
rs2156494	chr18	70518084	EGR2	1959	0.01	trans
rs17056922	chr18	73086804	EGR2	1959	0.01	trans
rs1540047	chr18	75047028	EGR2	1959	0.07	trans
rs2850843	chr18	75048905	EGR2	1959	0.07	trans
rs1540051	chr18	75049934	EGR2	1959	0.02	trans
rs16980096	chr19	15000921	EGR2	1959	0.07	trans
snp_a-2138575		0	EGR2	1959	0	trans
rs8103530	chr19	39172219	EGR2	1959	0.13	trans
rs234337	chr19	40458724	EGR2	1959	0	trans
rs234363	chr19	40474607	EGR2	1959	5.133E-4	trans
rs634346	chr20	3587203	EGR2	1959	0.19	trans
rs6417634	chr20	6408617	EGR2	1959	0.15	trans
rs6085552	chr20	6409004	EGR2	1959	0.15	trans
rs16997215	chr20	16101890	EGR2	1959	0.02	trans
snp_a-4254460		0	EGR2	1959	0.02	trans
rs8113962	chr20	18995999	EGR2	1959	0.13	trans
rs1797040	chr20	23907743	EGR2	1959	0.01	trans
rs2424603		0	EGR2	1959	0.01	trans
rs6102879	chr20	41138766	EGR2	1959	0.02	trans
rs6026122	chr20	56769083	EGR2	1959	7.113E-4	trans
rs259991	chr20	57728347	EGR2	1959	0.06	trans
rs6015452	chr20	57782312	EGR2	1959	0.04	trans
rs6124034	chr20	59517206	EGR2	1959	0.04	trans
rs6124036	chr20	59517478	EGR2	1959	0.04	trans
rs4812237	chr20	59518040	EGR2	1959	0.01	trans
rs2847443	chr21	14595263	EGR2	1959	0.05	trans
rs2226440	chr21	18066174	EGR2	1959	0.1	trans
rs16992859	chr21	36507007	EGR2	1959	0.02	trans
rs2834872	chr21	36634845	EGR2	1959	0.01	trans
rs2834874	chr21	36641270	EGR2	1959	0.04	trans
rs2834875	chr21	36656119	EGR2	1959	0	trans
rs877910	chr21	36658376	EGR2	1959	0.01	trans
rs7284012	chr21	36664376	EGR2	1959	0.07	trans
rs6586271	chr21	44362641	EGR2	1959	0.03	trans
rs369613	chr22	22380717	EGR2	1959	0.06	trans
rs410285	chr22	22381767	EGR2	1959	0.06	trans
rs134028	chr22	28048448	EGR2	1959	1.896E-5	trans
rs5762317	chr22	28094988	EGR2	1959	0	trans
rs9968025	chr22	32321588	EGR2	1959	0.04	trans
rs5768165	chr22	48318197	EGR2	1959	0.03	trans
rs5768168	chr22	48319334	EGR2	1959	0.03	trans
rs5768173	chr22	48321475	EGR2	1959	0.03	trans
rs16978981	chrX	13538144	EGR2	1959	0.19	trans
rs7879159	chrX	19481591	EGR2	1959	0.1	trans
rs12006821	chrX	50424687	EGR2	1959	0.02	trans
rs5977652	chrX	131315199	EGR2	1959	0.15	trans
rs16992781	chrX	146460376	EGR2	1959	0.02	trans
rs4824295	chrX	146496881	EGR2	1959	0.01	trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
PMPCB	0.89	0.85
UQCRC2	0.88	0.85
DNAJA2	0.88	0.84
YPEL5	0.88	0.87
POLR3F	0.87	0.85
BTBD10	0.87	0.87
SARS	0.87	0.86
TMEM49	0.87	0.84
COPS3	0.86	0.83
RHOT1	0.86	0.83

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AF347015.2	-0.67	-0.59
AF347015.26	-0.67	-0.59
MT-CO2	-0.66	-0.57
AF347015.8	-0.65	-0.57
MT-CYB	-0.65	-0.57
AF347015.15	-0.64	-0.57
AF347015.33	-0.63	-0.57
AF347015.21	-0.63	-0.55
AF347015.18	-0.63	-0.63
AF347015.31	-0.62	-0.56

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0003700	transcription factor activity	IDA		14532282
GO:0005515	protein binding	IPI		14532282
GO:0008270	zinc ion binding	IEA		-
GO:0046872	metal ion binding	IEA		-
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0007420	brain development	TAS	Brain (GO term level: 7)	9537424
GO:0006355	regulation of transcription, DNA-dependent	IEA		-
GO:0006350	transcription	IEA		-
GO:0007422	peripheral nervous system development	TAS		9537424
GO:0007638	mechanosensory behavior	IEA		-
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005622	intracellular	IEA		-
GO:0005634	nucleus	IEA		-

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
BIOCARTA VIP PATHWAY	29	26	All SZGR 2.0 genes in this pathway
ST DIFFERENTIATION PATHWAY IN PC12 CELLS	45	35	All SZGR 2.0 genes in this pathway
PID IL4 2PATHWAY	65	43	All SZGR 2.0 genes in this pathway
PID NFAT TFPATHWAY	47	39	All SZGR 2.0 genes in this pathway
PID TAP63 PATHWAY	54	40	All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY	396	292	All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	72	53	All SZGR 2.0 genes in this pathway
ZHONG RESPONSE TO AZACITIDINE AND TSA UP	183	119	All SZGR 2.0 genes in this pathway
GAL LEUKEMIC STEM CELL DN	244	153	All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP	233	161	All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC UP	185	126	All SZGR 2.0 genes in this pathway
NAGASHIMA NRG1 SIGNALING UP	176	123	All SZGR 2.0 genes in this pathway
NAGASHIMA EGF SIGNALING UP	58	40	All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC DN	537	339	All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 UP	64	46	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS DN	508	354	All SZGR 2.0 genes in this pathway
GESERICK TERT TARGETS DN	21	16	All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN	232	154	All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP	1142	669	All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP	612	367	All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS G UP	238	135	All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 3 4WK UP	214	144	All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 4 5WK UP	271	175	All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK DN	79	54	All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL TGFB1 TARGETS UP	169	127	All SZGR 2.0 genes in this pathway
MCBRYAN TERMINAL END BUD UP	12	12	All SZGR 2.0 genes in this pathway
CHASSOT SKIN WOUND	10	9	All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS	1174	695	All SZGR 2.0 genes in this pathway
PEREZ TP63 TARGETS	355	243	All SZGR 2.0 genes in this pathway
PEREZ TP53 AND TP63 TARGETS	205	145	All SZGR 2.0 genes in this pathway
DIRMEIER LMP1 RESPONSE EARLY	66	48	All SZGR 2.0 genes in this pathway
DAWSON METHYLATED IN LYMPHOMA TCL1	59	45	All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP	769	437	All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP	1037	673	All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS	1038	678	All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3	1118	744	All SZGR 2.0 genes in this pathway
KIM GERMINAL CENTER T HELPER UP	66	42	All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION DN	66	47	All SZGR 2.0 genes in this pathway
ZHANG TARGETS OF EWSR1 FLI1 FUSION	88	68	All SZGR 2.0 genes in this pathway
GALINDO IMMUNE RESPONSE TO ENTEROTOXIN	85	67	All SZGR 2.0 genes in this pathway
HESS TARGETS OF HOXA9 AND MEIS1 DN	77	48	All SZGR 2.0 genes in this pathway
STAEGE EWING FAMILY TUMOR	33	22	All SZGR 2.0 genes in this pathway
JIANG AGING CEREBRAL CORTEX UP	36	27	All SZGR 2.0 genes in this pathway
SARTIPY NORMAL AT INSULIN RESISTANCE UP	34	27	All SZGR 2.0 genes in this pathway
ABE VEGFA TARGETS	20	15	All SZGR 2.0 genes in this pathway
SAFFORD T LYMPHOCYTE ANERGY	87	54	All SZGR 2.0 genes in this pathway
ABE VEGFA TARGETS 30MIN	29	21	All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED	1022	619	All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED	1229	713	All SZGR 2.0 genes in this pathway
WANG LSD1 TARGETS DN	39	30	All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS SILENCED BY METHYLATION UP	461	298	All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS DN	543	317	All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN	593	372	All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN	591	366	All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 3D UP	210	124	All SZGR 2.0 genes in this pathway
CHENG IMPRINTED BY ESTRADIOL	110	68	All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP	430	288	All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN UP	439	257	All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL CULTURED VS FRESH UP	425	298	All SZGR 2.0 genes in this pathway
LIN NPAS4 TARGETS DN	68	48	All SZGR 2.0 genes in this pathway
VILIMAS NOTCH1 TARGETS UP	52	41	All SZGR 2.0 genes in this pathway
SEKI INFLAMMATORY RESPONSE LPS UP	77	56	All SZGR 2.0 genes in this pathway
HUNSBERGER EXERCISE REGULATED GENES	31	26	All SZGR 2.0 genes in this pathway
LINDSTEDT DENDRITIC CELL MATURATION D	68	44	All SZGR 2.0 genes in this pathway
LEE RECENT THYMIC EMIGRANT	227	128	All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK	1210	725	All SZGR 2.0 genes in this pathway
MIKKELSEN DEDIFFERENTIATED STATE DN	7	7	All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3	1069	729	All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN	170	105	All SZGR 2.0 genes in this pathway
UZONYI RESPONSE TO LEUKOTRIENE AND THROMBIN	37	26	All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE	721	492	All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN	306	191	All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 30MIN UP	56	38	All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP A	898	516	All SZGR 2.0 genes in this pathway
MIYAGAWA TARGETS OF EWSR1 ETS FUSIONS UP	259	159	All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS UP	163	111	All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 1HR UP	34	26	All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 10HR UP	199	143	All SZGR 2.0 genes in this pathway
PHONG TNF TARGETS UP	63	43	All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE VIA P38 COMPLETE	227	151	All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP	289	184	All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL UP	489	314	All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF	516	308	All SZGR 2.0 genes in this pathway
HECKER IFNB1 TARGETS	95	54	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	907	913	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	858	864	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-137	579	586	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-137	579	586	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-141/200a	1029	1035	1A	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	1029	1035	1A	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-142-3p	73	79	m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-150	401	408	1A,m8	hsa-miR-150	UCUCCCAACCCUUGUACCAGUG
miR-17-5p/20/93.mr/106/519.d	458	465	1A,m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-224	1019	1026	1A,m8	hsa-miR-224	CAAGUCACUAGUGGUUCCGUUUA
miR-25/32/92/363/367	612	618	m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-324-5p	826	832	1A	hsa-miR-324-5p	CGCAUCCCCUAGGGCAUUGGUGU
miR-34b	962	968	1A	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-377	864	870	m8	hsa-miR-377	AUCACACAAAGGCAACUUUUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.

Gene Page: EGR2