Gene Page: EYA1

Summary
GeneID  2138
Symbol  EYA1
Synonyms  BOP|BOR|MGC141875
Description  eyes absent homolog 1 (Drosophila)
See related  HGNC:3519|MIM:601653|Ensembl:ENSG00000104313|HPRD:03388|
Locus tag  -
Gene type  protein-coding
Map location  8q13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PRLR0.970.15
CP0.970.62
KCNJ130.960.28
CLIC60.950.47
SLC5A50.940.38
SLC13A40.910.30
ABCA40.900.40
FOLR10.880.33
RBM470.870.16
TRPV40.870.22
Top 10 negatively co-expressed genes
NR2C2AP-0.12-0.54
OLFM2-0.12-0.43
PLEKHO1-0.12-0.52
ALKBH2-0.12-0.54
ASGR1-0.12-0.41
STMN1-0.12-0.45
AC009133.1-0.11-0.46
RFC2-0.11-0.45
TUBB2B-0.11-0.53
MPND-0.11-0.35
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000287magnesium ion bindingIEA-
GO:0003824catalytic activityIEA-
GO:0005515protein bindingIEA-
GO:0004725protein tyrosine phosphatase activityIEA-
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0045664regulation of neuron differentiationIEAneuron, neurogenesis (GO term level: 9)-
GO:0001657ureteric bud developmentIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0006470protein amino acid dephosphorylationIEA-
GO:0009887organ morphogenesisIEA-
GO:0009653anatomical structure morphogenesisTAS9020840 
GO:0008152metabolic processIEA-
GO:0007605sensory perception of soundTAS9020840 
GO:0007389pattern specification processIEA-
GO:0007275multicellular organismal developmentIEA-
GO:0043066negative regulation of apoptosisIEA-
GO:0042472inner ear morphogenesisIEA-
GO:0045165cell fate commitmentIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
SIX1BOS3 | DFNA23 | TIP39SIX homeobox 1-HPRD,BioGRID11734542 |12874121 
SIX3HPE2SIX homeobox 3-HPRD10490620 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP 255177All SZGR genes in this pathway
DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP 6437All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN 329219All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP 8351All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON 13282All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN 163115All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_UP 9864All SZGR genes in this pathway
LU_AGING_BRAIN_UP 262186All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_UP 428266All SZGR genes in this pathway
KONDO_PROSTATE_CANCER_WITH_H3K27ME3 19693All SZGR genes in this pathway
BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 9175All SZGR genes in this pathway
BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_DN 3823All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN 264159All SZGR genes in this pathway
RUIZ_TNC_TARGETS_UP 153107All SZGR genes in this pathway
LI_WILMS_TUMOR 2712All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway
PLASARI_TGFB1_TARGETS_10HR_DN 244157All SZGR genes in this pathway
RAO_BOUND_BY_SALL4 227149All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN 308187All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101181018161Ahsa-miR-101UACAGUACUGUGAUAACUGAAG
hsa-miR-101UACAGUACUGUGAUAACUGAAG
hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-124.1849855m8hsa-miR-124aUUAAGGCACGCGGUGAAUGCCA
miR-124/5068488551A,m8hsa-miR-506UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brainUAAGGCACGCGGUGAAUGCC
miR-1282002061Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-144181018161Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-15/16/195/424/497164616531A,m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
miR-2197057121A,m8hsa-miR-219brainUGAUUGUCCAAACGCAAUUCU
miR-23326332m8hsa-miR-23abrainAUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrainAUCACAUUGCCAGGGAUUACC
miR-272822881Ahsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-3233263321Ahsa-miR-323brainGCACAUUACACGGUCGACCUCU
miR-369-3p108110881A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-37410821088m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
miR-493-5p691697m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-503164716531Ahsa-miR-503UAGCAGCGGGAACAGUUCUGCAG
miR-543229235m8hsa-miR-543AAACAUUCGCGGUGCACUUCU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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