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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: AFF2

Summary

GeneID

2334

Symbol

AFF2

Synonyms

FMR2|FRAXE|MRX2|OX19

Description

AF4/FMR2 family, member 2

Locus tag

Gene type

protein-coding

Map location

Xq28

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

HCK

0.83

0.71

CD68

0.81

0.72

CD14

0.81

0.75

ITGB2

0.80

0.74

TREM2

0.79

0.75

FCGR1A

0.76

0.64

VSIG4

0.76

0.68

NCKAP1L

0.76

0.67

LAPTM5

0.75

0.76

PGDS

0.74

Top 10 negatively co-expressed genes

AC010300.1

-0.30

-0.41

AC005921.3

-0.26

-0.39

AF347015.18

-0.26

-0.21

AP000769.2

-0.26

-0.35

AF347015.26

-0.26

-0.21

MALAT1

-0.26

-0.33

AC016705.1

-0.26

-0.31

C10orf108

-0.25

-0.30

ERVWE1

-0.25

-0.31

MICALL2

-0.24

-0.23

Gene Ontology

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007420

brain development

TAS

Brain (GO term level: 7)

8673086

GO:0007611

learning or memory

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IDA

18029348

GO:0005737

cytoplasm

IDA

18029348

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP	177	110	All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK	1652	1023	All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK	1442	892	All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK	779	480	All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS	1038	678	All SZGR genes in this pathway
BENPORATH_EED_TARGETS	1062	725	All SZGR genes in this pathway
ROSS_AML_WITH_PML_RARA_FUSION	77	62	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_UP	71	48	All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN	543	317	All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN	593	372	All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN	591	366	All SZGR genes in this pathway
VALK_AML_CLUSTER_12	30	20	All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_1HR_UP	61	44	All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP	745	475	All SZGR genes in this pathway
RATTENBACHER_BOUND_BY_CELF1	467	251	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	4499	4506	1A,m8	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	4499	4506	1A,m8	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-140	2907	2913	1A	hsa-miR-140^brain	AGUGGUUUUACCCUAUGGUAG
miR-142-3p	163	170	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-145	3586	3592	m8	hsa-miR-145	GUCCAGUUUUCCCAGGAAUCCCUU
miR-149	1740	1746	1A	hsa-miR-149^brain	UCUGGCUCCGUGUCUUCACUCC
miR-149	1740	1746	1A	hsa-miR-149^brain	UCUGGCUCCGUGUCUUCACUCC
miR-150	3575	3581	1A	hsa-miR-150	UCUCCCAACCCUUGUACCAGUG
miR-188	2696	2702	1A	hsa-miR-188	CAUCCCUUGCAUGGUGGAGGGU
miR-214	1530	1536	m8	hsa-miR-214^brain	ACAGCAGGCACAGACAGGCAG
miR-218	5631	5637	1A	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-24	3753	3759	1A	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-320	1902	1908	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-328	2869	2875	m8	hsa-miR-328^brain	CUGGCCCUCUCUGCCCUUCCGU
miR-33	9301	9307	1A	hsa-miR-33	GUGCAUUGUAGUUGCAUUG
miR-33	9301	9307	1A	hsa-miR-33b	GUGCAUUGCUGUUGCAUUGCA
miR-346	3785	3791	m8	hsa-miR-346^brain	UGUCUGCCCGCAUGCCUGCCUCU
miR-361	3996	4002	m8	hsa-miR-361^brain	UUAUCAGAAUCUCCAGGGGUAC
miR-369-3p	7116	7122	m8	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-409-3p	1413	1419	1A	hsa-miR-409-3p	CGAAUGUUGCUCGGUGAACCCCU
miR-448	226	232	m8	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-452	1630	1636	m8	hsa-miR-452	UGUUUGCAGAGGAAACUGAGAC
miR-494	4334	4340	1A	hsa-miR-494^brain	UGAAACAUACACGGGAAACCUCUU
miR-495	108	114	m8	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-539	232	239	1A,m8	hsa-miR-539	GGAGAAAUUAUCCUUGGUGUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.