Search results: The pahtway p3227 has 71 genes in the original annotation. Currently, there are 49 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
1390CREMCREM-2 | ICER | hCREM-2cAMP responsive element modulator10p11.21CV:PGCnp
DMG:Wockner_2014
PMID:cooccur
5599MAPK8JNK | JNK-46 | JNK1 | JNK1A2 | JNK21B1/2 | PRKM8 | SAPK1 | SAPK1cmitogen-activated protein kinase 810q11.22CV:PGCnp
DNM:Fromer_2014
Network
CompositeSet
8945BTRCBETA-TRCP | FBW1A | FBXW1 | FBXW1A | FWD1 | bTrCP | bTrCP1 | betaTrCPbeta-transducin repeat containing E3 ubiquitin protein ligase10q24.32CV:PGCnp
406ARNTLBMAL1 | BMAL1c | JAP3 | MOP3 | PASD3 | TIC | bHLHe5aryl hydrocarbon receptor nuclear translocator like11p15CV:GWAScat
CV:GWASdb
CV:PGCnp
PMID:cooccur
3665IRF7IMD39 | IRF-7H | IRF7A | IRF7B | IRF7C | IRF7Hinterferon regulatory factor 711p15.5CV:PGCnp
PMID:cooccur
2011MARK2EMK-1 | EMK1 | PAR-1 | Par-1b | Par1bmicrotubule affinity regulating kinase 211q13.1CV:PGCnp
DMG:Wockner_2014
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
3359HTR3A5-HT-3 | 5-HT3A | 5-HT3R | 5HT3R | HTR35-hydroxytryptamine receptor 3A11q23.1ADT:Sun_2012
Association
CV:PGCnp
GO_Annotation
GR_COR
GR_Ng
GR_WM
GSMA_I
PMID:cooccur
LIGAND GATED ION SIGNALING
9854C2CD2LDLNB23 | TMEM24C2CD2 like11q23.3CV:PGCnp
DEG:Maycox_2009
CompositeSet
Darnell FMRP targets
3312HSPA8HEL-33 | HEL-S-72p | HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP-1 | LAP1 | NIP71heat shock protein family A (Hsp70) member 811q24.1CV:PGCnp
DNM:Fromer_2014
Expression
GSMA_I
PMID:cooccur
RNA AND PROTEIN SYNTHESIS
CompositeSet
2597GAPDHG3PD | GAPD | HEL-S-162ePglyceraldehyde-3-phosphate dehydrogenase12p13DMG:Wockner_2014
Network
PMID:cooccur
CELL METABOLISM
G2Cdb.human_mitochondria
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
1280COL2A1ANFH | AOM | COL11A3 | SEDC | STL1collagen type II alpha 112q13.11CV:GWAScat
CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
429ASCL1ASH1 | HASH1 | MASH1 | bHLHa46achaete-scute family bHLH transcription factor 112q23.2CV:PGCnp
GO_Annotation
PMID:cooccur
8638OASLOASLd | TRIP-14 | TRIP14 | p59 OASL | p59-OASL | p59OASL2'-5'-oligoadenylate synthetase like12q24.2CV:PGCnp
4860PNPNP | PRO1837 | PUNPpurine nucleoside phosphorylase14q13.1CV:GWAScat
GSMA_I
Network
PMID:cooccur
23368PPP1R13BASPP1 | p53BP2-like | p85protein phosphatase 1 regulatory subunit 13B14q32.33CV:PGCnp
DMG:vanEijk_2014
DMG:Wockner_2014
DNM:Ambalavanan_2016
5607MAP2K5HsT17454 | MAPKK5 | MEK5 | PRKMK5mitogen-activated protein kinase kinase 515q23CV:PGCnp
10232MSLNMPF | SMRPmesothelin16p13.3CV:PGCnp
DMG:Wockner_2014
654780SFPQ-splicing factor proline/glutamine-rich16q24.1CV:PGCnp
CV:PheWAS
DMG:Jaffe_2016
4239MFAP4-microfibrillar associated protein 417p11.2CV:PGCnp
GO_Annotation
1267CNPCNP12',3'-cyclic nucleotide 3' phosphodiesterase17q21Association
GO_Annotation
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_clathrin
G2Cdb.human_Synaptosome
G2Cdb.human_TAP-PSD-95-CORE
CompositeSet
Darnell FMRP targets
23210JMJD6PSR | PTDSR | PTDSR1jumonji domain containing 617q25CV:PGCnp
DMG:Jaffe_2016
Ascano FMRP targets
Chromatin Remodeling Genes
25804LSM4GRP | YER112WLSM4 homolog, U6 small nuclear RNA and mRNA degradation associated19p13.11CV:GWASdb
CV:PGCnp
Network
4680CEACAM6CD66c | CEAL | NCAcarcinoembryonic antigen related cell adhesion molecule 619q13.2CV:PGCnp
PMID:cooccur
4352MPLC-MPL | CD110 | MPLV | THCYT2 | TPORMPL proto-oncogene, thrombopoietin receptor1p34CV:PGCnp
Expression
PMID:cooccur
6421SFPQPOMP100 | PPP1R140 | PSFsplicing factor proline/glutamine-rich1p34.3CV:PGCnp
CV:PheWAS
DMG:Jaffe_2016
4332MNDAPYHIN3myeloid cell nuclear differentiation antigen1q22CV:PGCnp
GR_Ng
GSMA_I
GSMA_IIA
PMID:cooccur
722C4BPAC4BP | PRPcomplement component 4 binding protein alpha1q32CV:PGCnp
Expression
PMID:cooccur
725C4BPBC4BPcomplement component 4 binding protein beta1q32CV:PGCnp
PMID:cooccur
5173PDYNADCA | PENKB | SCA23prodynorphin20p13Association
CV:PGCnp
DMG:Wockner_2014
GO_Annotation
PMID:cooccur
NEUROTROPHIN SIGNALING
4599MX1IFI-78K | IFI78 | MX | MxAMX dynamin like GTPase 121q22.3CV:PGCnp
PMID:cooccur
6663SOX10DOM | PCWH | WS2E | WS4 | WS4CSRY-box 1022q13.1Association
DEG:Zhao_2015
DMG:Wockner_2014
GO_Annotation
GR_COR
GR_Ng
GR_WM
PMID:cooccur
5610EIF2AK2EIF2AK1 | PKR | PPP1R83 | PRKReukaryotic translation initiation factor 2 alpha kinase 22p22-p21CV:PGCnp
PMID:cooccur
23150FRMD4B6030440G05Rik | GRSP1FERM domain containing 4B3p14.1CV:PGCnp
Expression
6533SLC6A6TAUTsolute carrier family 6 member 63p25.1CV:PGCnp
DMG:Nishioka_2013
GO_Annotation
GSMA_I
CELL METABOLISM
1359CPA3MC-CPAcarboxypeptidase A33q24CV:PGCnp
4487MSX1ECTD3 | HOX7 | HYD1 | STHAG1msh homeobox 14p16.2CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
GO_Annotation
PMID:cooccur
1839HBEGFDTR | DTS | DTSF | HEGFLheparin binding EGF like growth factor5q23CV:PGCnp
GSMA_I
7726TRIM26AFP | RNF95 | ZNF173tripartite motif containing 266p21.3CV:GWAScat
CV:GWASdb
CV:PGCnp
GSMA_I
PMID:cooccur
8737RIPK1RIP | RIP-1 | RIP1receptor interacting serine/threonine kinase 16p25.2CV:PGCnp
DMG:Jaffe_2016
GSMA_I
10690FUT9Fuc-TIXfucosyltransferase 9 (alpha (1,3) fucosyltransferase)6q16CV:GWAScat
CV:GWASdb
CV:PGC128
CV:PGCnp
262AMD1ADOMETDC | AMD | SAMDCadenosylmethionine decarboxylase 16q21CV:PGCnp
DMG:Wockner_2014
3482IGF2RCD222 | CI-M6PR | CIMPR | M6P-R | M6P/IGF2R | MPR 300 | MPR1 | MPR300 | MPRIinsulin like growth factor 2 receptor6q26CV:PGCnp
DMG:Montano_2016
PMID:cooccur
Ascano FMRP targets
60ACTBBRWS1 | PS1TP5BP1actin, beta7p22CV:PGCnp
Network
PMID:cooccur
STRUCTURAL PLASTICITY
CompositeSet
Darnell FMRP targets
2146EZH2ENX-1 | ENX1 | EZH1 | EZH2b | KMT6 | KMT6A | WVS | WVS2enhancer of zeste 2 polycomb repressive complex 2 subunit7q35-q36CV:PGCnp
DMG:Wockner_2014
Network
Chromatin Remodeling Genes
3456IFNB1IFB | IFF | IFN-beta | IFNBinterferon, beta 1, fibroblast9p21CV:GWASdb
CV:PGCnp
2203FBP1FBPfructose-bisphosphatase 19q22.3CV:GWASdb
CV:PGCnp
PMID:cooccur
4958OMDOSAD | SLRR2Costeomodulin9q22.31CV:PGCnp
PMID:cooccur
5730PTGDSL-PGDS | LPGDS | PDS | PGD2 | PGDS | PGDS2prostaglandin D2 synthase9q34.2-q34.3PMID:cooccur
2334AFF2FMR2 | FMR2P | FRAXE | MRX2 | OX19AF4/FMR2 family member 2Xq28CV:GWASdb
CV:PGCnp
GO_Annotation
Potential synaptic genes