Summary ?
GeneID25786
SymbolDGCR11
SynonymsDGS-D
DescriptionDiGeorge syndrome critical region gene 11 (non-protein coding)
ReferenceHGNC:HGNC:17226|Ensembl:ENSG00000273311|
Gene typencRNA
Map location22q11.21
Pascal p-value0.008
eGeneHypothalamus

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
NUMB0.840.89
TEX20.830.85
ARHGEF90.820.85
PHACTR10.820.84
GAS70.820.84
GFOD10.810.84
LANCL10.810.84
PPP3CA0.810.84
MCTP10.810.81
NFAT50.810.85
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
RHOC-0.52-0.59
DBI-0.50-0.57
C1orf54-0.45-0.51
ST20-0.45-0.47
GNG11-0.44-0.46
IL32-0.44-0.50
AF347015.21-0.44-0.41
PSME2-0.44-0.44
RAB34-0.43-0.47
C1orf61-0.42-0.48

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
DOANE RESPONSE TO ANDROGEN DN 241146All SZGR 2.0 genes in this pathway
GEORGES TARGETS OF MIR192 AND MIR215 893528All SZGR 2.0 genes in this pathway
MANALO HYPOXIA DN 289166All SZGR 2.0 genes in this pathway
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 419273All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR DN 3619All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725838All SZGR 2.0 genes in this pathway