Gene Page: DGCR11
Summary ?
GeneID | 25786 |
Symbol | DGCR11 |
Synonyms | DGS-D |
Description | DiGeorge syndrome critical region gene 11 (non-protein coding) |
Reference | HGNC:HGNC:17226|Ensembl:ENSG00000273311| |
Gene type | ncRNA |
Map location | 22q11.21 |
Pascal p-value | 0.008 |
eGene | Hypothalamus |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
NUMB | 0.84 | 0.89 |
TEX2 | 0.83 | 0.85 |
ARHGEF9 | 0.82 | 0.85 |
PHACTR1 | 0.82 | 0.84 |
GAS7 | 0.82 | 0.84 |
GFOD1 | 0.81 | 0.84 |
LANCL1 | 0.81 | 0.84 |
PPP3CA | 0.81 | 0.84 |
MCTP1 | 0.81 | 0.81 |
NFAT5 | 0.81 | 0.85 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RHOC | -0.52 | -0.59 |
DBI | -0.50 | -0.57 |
C1orf54 | -0.45 | -0.51 |
ST20 | -0.45 | -0.47 |
GNG11 | -0.44 | -0.46 |
IL32 | -0.44 | -0.50 |
AF347015.21 | -0.44 | -0.41 |
PSME2 | -0.44 | -0.44 |
RAB34 | -0.43 | -0.47 |
C1orf61 | -0.42 | -0.48 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
DOANE RESPONSE TO ANDROGEN DN | 241 | 146 | All SZGR 2.0 genes in this pathway |
GEORGES TARGETS OF MIR192 AND MIR215 | 893 | 528 | All SZGR 2.0 genes in this pathway |
MANALO HYPOXIA DN | 289 | 166 | All SZGR 2.0 genes in this pathway |
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 | 419 | 273 | All SZGR 2.0 genes in this pathway |
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR DN | 36 | 19 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |