Summary ?
GeneID2984
SymbolGUCY2C
SynonymsDIAR6|GUC2C|MECIL|MUCIL|STAR
Descriptionguanylate cyclase 2C
ReferenceMIM:601330|HGNC:HGNC:4688|Ensembl:ENSG00000070019|HPRD:07529|Vega:OTTHUMG00000168732
Gene typeprotein-coding
Map location12p12
Pascal p-value0.022

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
S100B0.530.60
CTSH0.530.59
MUSTN10.520.57
SERPINB60.500.56
RERGL0.500.53
TNFSF100.490.57
PPP1R14A0.480.57
S100A130.480.55
GSDMD0.480.54
PSMB90.480.59
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
NOC2L-0.51-0.61
STRN4-0.48-0.58
RNF40-0.47-0.57
GTF2F1-0.47-0.57
DAZAP1-0.47-0.59
PA2G4-0.47-0.58
KIAA1967-0.47-0.56
NEURL4-0.47-0.56
MKRN1-0.47-0.56
C7orf26-0.47-0.58

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG PURINE METABOLISM 15996All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY UP 430232All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
ROVERSI GLIOMA LOH REGIONS 4430All SZGR 2.0 genes in this pathway
SHIPP DLBCL CURED VS FATAL DN 4530All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882572All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER WITH H3K27ME3 UP 295149All SZGR 2.0 genes in this pathway
FIRESTEIN PROLIFERATION 175125All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305895All SZGR 2.0 genes in this pathway