Gene Page: SERTAD1

Summary ?
GeneID29950
SymbolSERTAD1
SynonymsSEI1|TRIP-Br1
DescriptionSERTA domain containing 1
ReferenceHGNC:HGNC:17932|HPRD:15326|
Gene typeprotein-coding
Map location19q13.1-q13.2
Pascal p-value0.564
Sherlock p-value0.109
Fetal beta-0.197
DMG1 (# studies)
eGeneMyers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
DMG:Nishioka_2013Genome-wide DNA methylation analysisThe authors investigated the methylation profiles of DNA in peripheral blood cells from 18 patients with first-episode schizophrenia (FESZ) and from 15 normal controls. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg250600201940932140SERTAD1-0.0210.96DMG:Nishioka_2013

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs12030788chr166768128SERTAD1299500.09trans
rs6666937chr1170286842SERTAD1299500.09trans
rs11127467chr212993SERTAD1299500trans
rs16827037chr3117203284SERTAD1299503.733E-4trans
rs614566chr3182847389SERTAD1299500.17trans
rs7631640chr3182883407SERTAD1299500.16trans
rs1009606chr65726368SERTAD1299500.08trans
rs3888778chr630529621SERTAD1299500.06trans
rs2239516chr630578047SERTAD1299500.16trans
rs6904236chr630596134SERTAD1299500.1trans
rs887719chr721184272SERTAD1299500.08trans
rs320082chr729105404SERTAD1299501.407E-4trans
rs317720chr729110633SERTAD1299500.01trans
rs317714chr729115553SERTAD1299503.901E-5trans
rs317724chr729120565SERTAD1299500.01trans
rs1419793chr734697630SERTAD1299509.321E-5trans
rs16886605chr8115894398SERTAD1299500.09trans
rs10282827chr8138034102SERTAD1299500.02trans
rs10834670chr1125404015SERTAD1299501.418E-5trans
rs10834671chr1125404269SERTAD1299502.518E-5trans
rs11019015chr1190157517SERTAD1299500.01trans
rs11066476chr12113465366SERTAD1299500.17trans
rs4497566chr1351694324SERTAD1299506.706E-5trans
rs11846180chr1451377031SERTAD1299500.11trans
rs13076870SERTAD1299500.07trans
rs11158850chr1470757171SERTAD1299500.02trans
rs1846326chr1528063877SERTAD1299500.16trans
rs12452652chr1772235560SERTAD1299500.02trans
rs9646596chr1853049211SERTAD1299500.02trans
rs11152369chr1853066327SERTAD1299500.11trans
rs1230712chr1854992531SERTAD1299500.05trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
WANG LMO4 TARGETS UP 372227All SZGR 2.0 genes in this pathway
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE UP 13680All SZGR 2.0 genes in this pathway
JAZAG TGFB1 SIGNALING VIA SMAD4 UP 10866All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037673All SZGR 2.0 genes in this pathway
INGRAM SHH TARGETS DN 6441All SZGR 2.0 genes in this pathway
BENPORATH MYC MAX TARGETS 775494All SZGR 2.0 genes in this pathway
YAO HOXA10 TARGETS VIA PROGESTERONE UP 7958All SZGR 2.0 genes in this pathway
MARTINEZ RESPONSE TO TRABECTEDIN UP 7149All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 8 8657All SZGR 2.0 genes in this pathway
BRACHAT RESPONSE TO CAMPTOTHECIN UP 2818All SZGR 2.0 genes in this pathway
MONNIER POSTRADIATION TUMOR ESCAPE DN 373196All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229713All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE DN 409268All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354216All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER DN 540340All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN 274165All SZGR 2.0 genes in this pathway
LIN NPAS4 TARGETS DN 6848All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL IL3RA 96All SZGR 2.0 genes in this pathway
DANG BOUND BY MYC 1103714All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721492All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 7 7646All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP 307182All SZGR 2.0 genes in this pathway
QI HYPOXIA 14096All SZGR 2.0 genes in this pathway
LIU IL13 PRIMING MODEL 1511All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF 516308All SZGR 2.0 genes in this pathway