Gene Page: HNRNPC

Summary
GeneID  3183
Symbol  HNRNPC
Synonyms  C1|C2|HNRNP|HNRPC|MGC104306|MGC105117|MGC117353|MGC131677|SNRPC
Description  heterogeneous nuclear ribonucleoprotein C (C1/C2)
See related  HGNC:5035|MIM:164020|Ensembl:ENSG00000092199|HPRD:01243|
Locus tag  -
Gene type  protein-coding
Map location  14q11.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0003723RNA bindingNAS9731529 
GO:0042802identical protein bindingIPI16189514 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000398nuclear mRNA splicing, via spliceosomeEXP12226669 
GO:0000398nuclear mRNA splicing, via spliceosomeIC9731529 
GO:0008380RNA splicingTAS3110598 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIEA-
GO:0005681spliceosomeIDA9731529 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AP1M1AP47 | CLAPM2 | CLTNM | MU-1Aadaptor-related protein complex 1, mu 1 subunitTwo-hybridBioGRID16189514 
CCDC85BDIPAcoiled-coil domain containing 85BTwo-hybridBioGRID16189514 
CNBPCNBP1 | DM2 | FLJ11631 | PROMM | RNF163 | ZCCHC22 | ZNF9CCHC-type zinc finger, nucleic acid binding proteinAffinity Capture-MSBioGRID17353931 
FXR2FMR1L2fragile X mental retardation, autosomal homolog 2Two-hybridBioGRID16189514 
GRB2ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084growth factor receptor-bound protein 2-HPRD,BioGRID9516488 
HNRNPCC1 | C2 | HNRNP | HNRPC | MGC104306 | MGC105117 | MGC117353 | MGC131677 | SNRPCheterogeneous nuclear ribonucleoprotein C (C1/C2)Affinity Capture-Western
Reconstituted Complex
Two-hybrid		BioGRID10772858 |16189514 
KPNA3IPOA4 | SRP1gamma | SRP4 | hSRP1karyopherin alpha 3 (importin alpha 4)Two-hybridBioGRID16189514 
KRASC-K-RAS | K-RAS2A | K-RAS2B | K-RAS4A | K-RAS4B | KI-RAS | KRAS1 | KRAS2 | NS3 | RASK2v-Ki-ras2 Kirsten rat sarcoma viral oncogene homologTwo-hybridBioGRID16189514 
LMO3DAT1 | MGC26081 | RBTN3 | RBTNL2 | RHOM3 | Rhom-3LIM domain only 3 (rhombotin-like 2)Two-hybridBioGRID16189514 
MYCbHLHe39 | c-Mycv-myc myelocytomatosis viral oncogene homolog (avian)Affinity Capture-MSBioGRID17353931 
PDGFBFLJ12858 | PDGF2 | SIS | SSV | c-sisplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)-HPRD10409733 
PHKBDKFZp781E15103 | FLJ41698phosphorylase kinase, betaTwo-hybridBioGRID16189514 
PIN1DOD | UBL5peptidylprolyl cis/trans isomerase, NIMA-interacting 1Two-hybridBioGRID16189514 
PUF60FIR | FLJ31379 | RoBPI | SIAHBP1poly-U binding splicing factor 60KDaAffinity Capture-MSBioGRID17353931 
RALYLHNRPCL3RALY RNA binding protein-likeTwo-hybridBioGRID16189514 
RBM41FLJ11016 | FLJ13670 | bB383K5.1RNA binding motif protein 41Two-hybridBioGRID16189514 
SFRS12DKFZp564B176 | MGC133045 | SRrp508 | SRrp86splicing factor, arginine/serine-rich 12-HPRD14559993 
UBE2IC358B7.1 | P18 | UBC9ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)Two-hybridBioGRID16189514 
ZNF581FLJ22550 | HSPC189zinc finger protein 581Two-hybridBioGRID16189514 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_SPLICEOSOME 12872All SZGR genes in this pathway
PID_TELOMERASE_PATHWAY 6848All SZGR genes in this pathway
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 14077All SZGR genes in this pathway
REACTOME_MRNA_PROCESSING 16186All SZGR genes in this pathway
REACTOME_MRNA_SPLICING 11158All SZGR genes in this pathway
GARY_CD5_TARGETS_DN 431263All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
LAIHO_COLORECTAL_CANCER_SERRATED_UP 11271All SZGR genes in this pathway
BORCZUK_MALIGNANT_MESOTHELIOMA_UP 305185All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_DN 406230All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP 1278748All SZGR genes in this pathway
KIM_WT1_TARGETS_DN 459276All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_DN 228137All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
PUJANA_CHEK2_PCC_NETWORK 779480All SZGR genes in this pathway
WEI_MYCN_TARGETS_WITH_E_BOX 795478All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN 514330All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN 3222All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN 309206All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP 7752All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
ZHANG_RESPONSE_TO_CANTHARIDIN_DN 6946All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN 1011592All SZGR genes in this pathway
KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_4NQO_IN_WS 4026All SZGR genes in this pathway
KYNG_DNA_DAMAGE_UP 226164All SZGR genes in this pathway
KYNG_ENVIRONMENTAL_STRESS_RESPONSE_DN 2112All SZGR genes in this pathway
STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP 12589All SZGR genes in this pathway
MASSARWEH_TAMOXIFEN_RESISTANCE_UP 578341All SZGR genes in this pathway
DE_YY1_TARGETS_DN 9264All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 11865All SZGR genes in this pathway
GRADE_COLON_VS_RECTAL_CANCER_UP 3821All SZGR genes in this pathway
LEE_LIVER_CANCER_SURVIVAL_DN 175103All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP 4023All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SUBCLASS_S2 11574All SZGR genes in this pathway
CAIRO_HEPATOBLASTOMA_CLASSES_UP 605377All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 7646All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES 275155All SZGR genes in this pathway
KUMAR_AUTOPHAGY_NETWORK 7146All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-2085535591Ahsa-miR-208AUAAGACGAGCAAAAAGCUUGU
miR-2242542601Ahsa-miR-224CAAGUCACUAGUGGUUCCGUUUA
miR-299-5p6506561Ahsa-miR-299-5pUGGUUUACCGUCCCACAUACAU
miR-320411417m8hsa-miR-320AAAAGCUGGGUUGAGAGGGCGAA
miR-455171Ahsa-miR-455UAUGUGCCUUUGGACUACAUCG
miR-4995525591A,m8hsa-miR-499UUAAGACUUGCAGUGAUGUUUAA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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