Gene Page: KCNA7
Summary ?
| GeneID | 3743 |
| Symbol | KCNA7 |
| Synonyms | HAK6|KV1.7 |
| Description | potassium voltage-gated channel subfamily A member 7 |
| Reference | MIM:176268|HGNC:HGNC:6226|Ensembl:ENSG00000104848|HPRD:01445|Vega:OTTHUMG00000183343 |
| Gene type | protein-coding |
| Map location | 19q13.3 |
| Pascal p-value | 0.024 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SSTR3 | 0.89 | 0.76 |
| CIT | 0.86 | 0.81 |
| LRTM2 | 0.86 | 0.83 |
| RASSF3 | 0.86 | 0.70 |
| KCNC2 | 0.85 | 0.72 |
| GPR123 | 0.84 | 0.83 |
| PLBD2 | 0.83 | 0.80 |
| BTBD11 | 0.83 | 0.78 |
| NDRG4 | 0.81 | 0.84 |
| CACNA1G | 0.81 | 0.73 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C9orf46 | -0.39 | -0.53 |
| GTF3C6 | -0.39 | -0.48 |
| RBMX2 | -0.39 | -0.50 |
| EXOSC8 | -0.38 | -0.45 |
| RPL23A | -0.37 | -0.51 |
| HAUS4 | -0.36 | -0.42 |
| RPS20 | -0.36 | -0.55 |
| FAM36A | -0.36 | -0.37 |
| RPS23 | -0.36 | -0.47 |
| RPS6 | -0.35 | -0.49 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME NEURONAL SYSTEM | 279 | 221 | All SZGR 2.0 genes in this pathway |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 43 | 32 | All SZGR 2.0 genes in this pathway |
| REACTOME POTASSIUM CHANNELS | 98 | 68 | All SZGR 2.0 genes in this pathway |
| MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 | 1069 | 729 | All SZGR 2.0 genes in this pathway |
| MEISSNER NPC HCP WITH H3K4ME2 AND H3K27ME3 | 349 | 234 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN NPC HCP WITH H3K27ME3 | 341 | 243 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF HCP WITH H3K27ME3 | 590 | 403 | All SZGR 2.0 genes in this pathway |