SZGR2

Summary ?

GeneID	4087
Symbol	SMAD2
Synonyms	JV18\|JV18-1\|MADH2\|MADR2\|hMAD-2\|hSMAD2
Description	SMAD family member 2
Reference	MIM:601366\|HGNC:HGNC:6768\|Ensembl:ENSG00000175387\|HPRD:03221\|Vega:OTTHUMG00000132652
Gene type	protein-coding
Map location	18q21.1
Pascal p-value	0.047
Sherlock p-value	0.175
Fetal beta	0.181

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	Click to show details
Network	Shortest path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 1.0843

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0003690	double-stranded DNA binding	ISS		-
GO:0003700	transcription factor activity	IEA		-
GO:0008134	transcription factor binding	IPI		9702198
GO:0008134	transcription factor binding	ISS		-
GO:0016563	transcription activator activity	ISS		-
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0001707	mesoderm formation	ISS		-
GO:0006350	transcription	IEA		-
GO:0007242	intracellular signaling cascade	ISS		-
GO:0009952	anterior/posterior pattern formation	ISS		-
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	IMP		14555988
GO:0051098	regulation of binding	ISS		-
GO:0045165	cell fate commitment	ISS		-
GO:0048340	paraxial mesoderm morphogenesis	ISS		-
GO:0045892	negative regulation of transcription, DNA-dependent	IMP		14555988
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	ISS		-
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005829	cytosol	EXP		9311995 \|9865696 \|11100470
GO:0005622	intracellular	IEA		-
GO:0005634	nucleus	IEA		-
GO:0005654	nucleoplasm	EXP		10549282
GO:0005667	transcription factor complex	ISS		-
GO:0005737	cytoplasm	IEA		-

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACVR1B	ACTRIB \| ACVRLK4 \| ALK4 \| SKR2	activin A receptor, type IB	Affinity Capture-Western	BioGRID	9892009
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	Affinity Capture-Western	BioGRID	16362038
ANAPC10	APC10 \| DKFZp564L0562 \| DOC1	anaphase promoting complex subunit 10	Affinity Capture-Western Reconstituted Complex	BioGRID	15144564
ANAPC10	APC10 \| DKFZp564L0562 \| DOC1	anaphase promoting complex subunit 10	Smad2 interacts with APC10.	BIND	15144564
AXIN1	AXIN \| MGC52315	axin 1	-	HPRD	11438668
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	BRCA1 interacts with Smad2. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad2 from an unspecified species.	BIND	15735739
BRCA2	BRCC2 \| FACD \| FAD \| FAD1 \| FANCB \| FANCD \| FANCD1	breast cancer 2, early onset	Affinity Capture-Western	BioGRID	12165866
CAMK2G	CAMK \| CAMK-II \| CAMKG \| FLJ16043 \| MGC26678	calcium/calmodulin-dependent protein kinase II gamma	Biochemical Activity	BioGRID	11027280
CAV1	CAV \| MSTP085 \| VIP21	caveolin 1, caveolae protein, 22kDa	Co-fractionation	BioGRID	11102446
CDC16	APC6	cell division cycle 16 homolog (S. cerevisiae)	-	HPRD,BioGRID	11691834
CDC27	APC3 \| CDC27Hs \| D0S1430E \| D17S978E \| HNUC	cell division cycle 27 homolog (S. cerevisiae)	-	HPRD,BioGRID	11691834
CDK2	p33(CDK2)	cyclin-dependent kinase 2	CDK2 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and human CDK2.	BIND	15241418
CDK4	CMM3 \| MGC14458 \| PSK-J3	cyclin-dependent kinase 4	CDK4 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and mouse CDK4.	BIND	15241418
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad2 from an unspecified species.	BIND	15750622
CREBBP	CBP \| KAT3A \| RSTS	CREB binding protein	CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between CBP from an unspecified species and human Smad2.	BIND	9679056
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	-	HPRD,BioGRID	12000714
DAB2	DOC-2 \| DOC2 \| FLJ26626	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	-	HPRD,BioGRID	11387212
DVL1	DVL \| MGC54245	dishevelled, dsh homolog 1 (Drosophila)	-	HPRD,BioGRID	12650946
E2F4	E2F-4	E2F transcription factor 4, p107/p130-binding	-	HPRD	12150994
EID2	CRI2 \| EID-2 \| MGC20452	EP300 interacting inhibitor of differentiation 2	-	HPRD,BioGRID	14612439
EP300	KAT3B \| p300	E1A binding protein p300	p300 interacts with Smad2. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad2.	BIND	9679056
EP300	KAT3B \| p300	E1A binding protein p300	Affinity Capture-Western	BioGRID	10199400 \|11371641
EP300	KAT3B \| p300	E1A binding protein p300	-	HPRD	11264182
ERBB2IP	ERBIN \| LAP2	erbb2 interacting protein	-	HPRD,BioGRID	12650946
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	estrogen receptor 1	-	HPRD,BioGRID	11555647
FOXH1	FAST-1 \| FAST1	forkhead box H1	The SIM motif of FoxH1 interacts with Smad2. This interaction was modeled on a demonstrated interaction between human FoxH1 and Smad2 from an unspecified species.	BIND	15750622
FOXH1	FAST-1 \| FAST1	forkhead box H1	FoxH1 interacts with Smad2. This interaction was modelled on a demonstrated interaction between FoxH1 from an unspecified species and Smad3 from an unspecified species.	BIND	15084259
FOXH1	FAST-1 \| FAST1	forkhead box H1	-	HPRD,BioGRID	9288972 \|9389648
FOXO3	AF6q21 \| DKFZp781A0677 \| FKHRL1 \| FKHRL1P2 \| FOXO2 \| FOXO3A \| MGC12739 \| MGC31925	forkhead box O3	-	HPRD	15084259
GLI3	ACLS \| GCPS \| PAP-A \| PAPA \| PAPA1 \| PAPB \| PHS \| PPDIV	GLI-Kruppel family member GLI3	-	HPRD	9843199
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	-	HPRD,BioGRID	10199400
HIPK2	DKFZp686K02111 \| FLJ23711 \| PRO0593	homeodomain interacting protein kinase 2	-	HPRD,BioGRID	12874272
HNF4A	FLJ39654 \| HNF4 \| HNF4a7 \| HNF4a8 \| HNF4a9 \| MODY \| MODY1 \| NR2A1 \| NR2A21 \| TCF \| TCF14	hepatocyte nuclear factor 4, alpha	-	HPRD	11229886
HOXA9	ABD-B \| HOX1 \| HOX1.7 \| HOX1G \| MGC1934	homeobox A9	-	HPRD,BioGRID	11042172
INSR	CD220 \| HHF5	insulin receptor	-	HPRD,BioGRID	9092546
JUN	AP-1 \| AP1 \| c-Jun	jun oncogene	-	HPRD,BioGRID	10220381 \|11371641
LEF1	DKFZp586H0919 \| TCF1ALPHA	lymphoid enhancer-binding factor 1	-	HPRD,BioGRID	10890911
LEMD3	MAN1	LEM domain containing 3	LEMD3 interacts with Smad2. This interaction was modelled on a demonstrated interaction between human LEMD3 and mouse Smad2.	BIND	15489854
MED15	ARC105 \| CAG7A \| CTG7A \| DKFZp686A2214 \| DKFZp762B1216 \| FLJ42282 \| FLJ42935 \| PCQAP \| TIG-1 \| TIG1 \| TNRC7	mediator complex subunit 15	-	HPRD	12167862
MEF2A	ADCAD1 \| RSRFC4 \| RSRFC9	myocyte enhancer factor 2A	-	HPRD,BioGRID	11160896
MEF2C	-	myocyte enhancer factor 2C	-	HPRD,BioGRID	11160896
MYC	bHLHe39 \| c-Myc	v-myc myelocytomatosis viral oncogene homolog (avian)	-	HPRD,BioGRID	11804592
NEDD9	CAS-L \| CAS2 \| CASL \| CASS2 \| HEF1 \| dJ49G10.2 \| dJ761I2.1	neural precursor cell expressed, developmentally down-regulated 9	-	HPRD,BioGRID	11118211
NFYC	CBF-C \| CBFC \| DKFZp667G242 \| FLJ45775 \| H1TF2A \| HAP5 \| HSM \| NF-YC	nuclear transcription factor Y, gamma	-	HPRD,BioGRID	12023901
NUP153	HNUP153 \| N153	nucleoporin 153kDa	-	HPRD	12191473
NUP214	CAIN \| CAN \| D9S46E \| MGC104525 \| N214	nucleoporin 214kDa	-	HPRD	12191473
PARD3	ASIP \| Baz \| Bazooka \| FLJ21015 \| PAR3 \| PAR3alpha \| PARD3A \| SE2-5L16 \| SE2-5LT1 \| SE2-5T2	par-3 partitioning defective 3 homolog (C. elegans)	-	HPRD	12650946
PARD3B	ALS2CR19 \| MGC16131 \| PAR3B \| PAR3L \| PAR3LC \| PAR3beta \| Par3Lb	par-3 partitioning defective 3 homolog B (C. elegans)	Reconstituted Complex	BioGRID	12650946
PIAS3	FLJ14651 \| ZMIZ5	protein inhibitor of activated STAT, 3	-	HPRD,BioGRID	14691252
PIAS4	FLJ12419 \| MGC35296 \| PIASY \| Piasg \| ZMIZ6	protein inhibitor of activated STAT, 4	Affinity Capture-Western	BioGRID	12815042
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	-	HPRD,BioGRID	15356634
PML	MYL \| PP8675 \| RNF71 \| TRIM19	promyelocytic leukemia	cPML interacts with Smad2.	BIND	15356634
RBL1	CP107 \| MGC40006 \| PRB1 \| p107	retinoblastoma-like 1 (p107)	-	HPRD	12150994
RUNX1	AML1 \| AML1-EVI-1 \| AMLCR1 \| CBFA2 \| EVI-1 \| PEBP2aB	runt-related transcription factor 1	Affinity Capture-Western	BioGRID	10531362
RUNX2	AML3 \| CBFA1 \| CCD \| CCD1 \| MGC120022 \| MGC120023 \| OSF2 \| PEA2aA \| PEBP2A1 \| PEBP2A2 \| PEBP2aA \| PEBP2aA1	runt-related transcription factor 2	-	HPRD,BioGRID	10531362
RUNX3	AML2 \| CBFA3 \| FLJ34510 \| MGC16070 \| PEBP2aC	runt-related transcription factor 3	Affinity Capture-Western	BioGRID	10531362
SKI	SKV	v-ski sarcoma viral oncogene homolog (avian)	c-Ski interacts with Smad2. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified source and human c-Ski.	BIND	10575014
SKI	SKV	v-ski sarcoma viral oncogene homolog (avian)	-	HPRD,BioGRID	10485843
SKIL	SNO \| SnoA \| SnoN	SKI-like oncogene	Smad2 interacts with SnoN. This interaction was modeled on a demonstrated interaction between SnoN from an unspecified source and human Smad2.	BIND	12426322
SKIL	SNO \| SnoA \| SnoN	SKI-like oncogene	-	HPRD,BioGRID	10531062 \|11691834
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	Smad2 interacts with Smad3. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad3 from an unspecified species.	BIND	9311995
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	SMAD3 interacts with SMAD2.	BIND	15761153
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	-	HPRD,BioGRID	9311995
SMAD4	DPC4 \| JIP \| MADH4	SMAD family member 4	-	HPRD,BioGRID	11274206
SMAD4	DPC4 \| JIP \| MADH4	SMAD family member 4	Smad4 interacts with Smad2.	BIND	15761153
SMAD4	DPC4 \| JIP \| MADH4	SMAD family member 4	Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species.	BIND	9311995
SMAD7	CRCS3 \| FLJ16482 \| MADH7 \| MADH8	SMAD family member 7	Phenotypic Suppression	BioGRID	9892009
SMURF2	DKFZp686F0270 \| MGC138150	SMAD specific E3 ubiquitin protein ligase 2	SMAD2 interacts with SMURF2.	BIND	15761153
SMURF2	DKFZp686F0270 \| MGC138150	SMAD specific E3 ubiquitin protein ligase 2	-	HPRD,BioGRID	11016919
SNIP1	FLJ12553 \| RP3-423B22.3 \| dJ423B22.2	Smad nuclear interacting protein 1	-	HPRD,BioGRID	10887155
SNW1	Bx42 \| MGC119379 \| NCOA-62 \| PRPF45 \| Prp45 \| SKIIP \| SKIP	SNW domain containing 1	SKIP interacts with Smad2. This interaction was modeled on a demonstrated interaction between human SKIP and Smad2 from an unspecified source.	BIND	11278756
SNW1	Bx42 \| MGC119379 \| NCOA-62 \| PRPF45 \| Prp45 \| SKIIP \| SKIP	SNW domain containing 1	-	HPRD,BioGRID	11278756
SP1	-	Sp1 transcription factor	-	HPRD,BioGRID	11114293
STRAP	MAWD \| PT-WD \| UNRIP	serine/threonine kinase receptor associated protein	-	HPRD,BioGRID	10757800
TGFBR1	AAT5 \| ACVRLK4 \| ALK-5 \| ALK5 \| LDS1A \| LDS2A \| SKR4 \| TGFR-1	transforming growth factor, beta receptor 1	-	HPRD	9525694
TGFBR1	AAT5 \| ACVRLK4 \| ALK-5 \| ALK5 \| LDS1A \| LDS2A \| SKR4 \| TGFR-1	transforming growth factor, beta receptor 1	Co-fractionation	BioGRID	11102446
TGFBR1	AAT5 \| ACVRLK4 \| ALK-5 \| ALK5 \| LDS1A \| LDS2A \| SKR4 \| TGFR-1	transforming growth factor, beta receptor 1	T-beta-RI interacts with Smad2.	BIND	15761153
TGFBRAP1	TRAP-1 \| TRAP1	transforming growth factor, beta receptor associated protein 1	-	HPRD	11278302
TGIF1	HPE4 \| MGC39747 \| MGC5066 \| TGIF	TGFB-induced factor homeobox 1	-	HPRD,BioGRID	10199400
TOB1	APRO6 \| MGC104792 \| MGC34446 \| PIG49 \| TOB \| TROB \| TROB1	transducer of ERBB2, 1	-	HPRD	11163184
ZEB1	AREB6 \| BZP \| DELTA-EF1 \| MGC133261 \| NIL-2-A \| NIL-2A \| NIL2A \| TCF8 \| ZEB \| ZFHEP \| ZFHX1A	zinc finger E-box binding homeobox 1	-	HPRD,BioGRID	12743038
ZEB2	KIAA0569 \| SIP-1 \| SIP1 \| SMADIP1 \| ZFHX1B	zinc finger E-box binding homeobox 2	-	HPRD	10400677
ZFYVE9	MADHIP \| NSP \| SARA \| SMADIP	zinc finger, FYVE domain containing 9	-	HPRD,BioGRID	9865696
ZNF8	HF.18 \| Zfp128	zinc finger protein 8	-	HPRD	12370310

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG CELL CYCLE	128	84	All SZGR 2.0 genes in this pathway
KEGG WNT SIGNALING PATHWAY	151	112	All SZGR 2.0 genes in this pathway
KEGG TGF BETA SIGNALING PATHWAY	86	64	All SZGR 2.0 genes in this pathway
KEGG ADHERENS JUNCTION	75	53	All SZGR 2.0 genes in this pathway
KEGG PATHWAYS IN CANCER	328	259	All SZGR 2.0 genes in this pathway
KEGG COLORECTAL CANCER	62	47	All SZGR 2.0 genes in this pathway
KEGG PANCREATIC CANCER	70	56	All SZGR 2.0 genes in this pathway
BIOCARTA TGFB PATHWAY	19	14	All SZGR 2.0 genes in this pathway
PID SMAD2 3NUCLEAR PATHWAY	82	63	All SZGR 2.0 genes in this pathway
PID GLYPICAN 1PATHWAY	27	20	All SZGR 2.0 genes in this pathway
PID SMAD2 3PATHWAY	17	13	All SZGR 2.0 genes in this pathway
PID MYC REPRESS PATHWAY	63	52	All SZGR 2.0 genes in this pathway
PID TGFBR PATHWAY	55	38	All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY	396	292	All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY NODAL	18	11	All SZGR 2.0 genes in this pathway
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	23	13	All SZGR 2.0 genes in this pathway
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	27	17	All SZGR 2.0 genes in this pathway
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	26	16	All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	38	26	All SZGR 2.0 genes in this pathway
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	20	14	All SZGR 2.0 genes in this pathway
REACTOME GENERIC TRANSCRIPTION PATHWAY	352	181	All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	63	42	All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL UP	94	59	All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP	1382	904	All SZGR 2.0 genes in this pathway
BORCZUK MALIGNANT MESOTHELIOMA UP	305	185	All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS DN	310	188	All SZGR 2.0 genes in this pathway
TURJANSKI MAPK1 AND MAPK2 TARGETS	12	10	All SZGR 2.0 genes in this pathway
BREUHAHN GROWTH FACTOR SIGNALING IN LIVER CANCER	22	19	All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN	584	395	All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK	1652	1023	All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK	1442	892	All SZGR 2.0 genes in this pathway
BENPORATH PROLIFERATION	147	80	All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS UP	424	268	All SZGR 2.0 genes in this pathway
POMEROY MEDULLOBLASTOMA DESMOPLASIC VS CLASSIC UP	62	38	All SZGR 2.0 genes in this pathway
FAELT B CLL WITH VH3 21 DN	49	29	All SZGR 2.0 genes in this pathway
ZAMORA NOS2 TARGETS UP	69	41	All SZGR 2.0 genes in this pathway
RAMALHO STEMNESS UP	206	118	All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP	1691	1088	All SZGR 2.0 genes in this pathway
HEDENFALK BREAST CANCER BRCA1 VS BRCA2	163	113	All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV SCC UP	123	75	All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3	720	440	All SZGR 2.0 genes in this pathway
TOYOTA TARGETS OF MIR34B AND MIR34C	463	262	All SZGR 2.0 genes in this pathway
GU PDEF TARGETS UP	71	49	All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS DN	366	257	All SZGR 2.0 genes in this pathway
BOYAULT LIVER CANCER SUBCLASS G3 UP	188	121	All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S1	237	159	All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN	1972	1213	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	3772	3778	m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-128	8336	8343	1A,m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	8336	8343	1A,m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-142-5p	413	419	1A	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-148/152	8334	8340	m8	hsa-miR-148a	UCAGUGCACUACAGAACUUUGU
				hsa-miR-152^brain	UCAGUGCAUGACAGAACUUGGG
				hsa-miR-148b	UCAGUGCAUCACAGAACUUUGU
miR-151	189	195	1A	hsa-miR-151^brain	ACUAGACUGAAGCUCCUUGAGG
miR-155	8694	8701	1A,m8	hsa-miR-155	UUAAUGCUAAUCGUGAUAGGGG
miR-18	137	143	m8	hsa-miR-18a	UAAGGUGCAUCUAGUGCAGAUA
miR-18	137	143	m8	hsa-miR-18b	UAAGGUGCAUCUAGUGCAGUUA
miR-24*	404	410	1A	hsa-miR-189	GUGCCUACUGAGCUGAUAUCAGU
miR-27	8337	8343	m8	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	8337	8343	m8	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-329	377	383	m8	hsa-miR-329^brain	AACACACCUGGUUAACCUCUUU
miR-93.hd/291-3p/294/295/302/372/373/520	112	118	m8	hsa-miR-93^brain	AAAGUGCUGUUCGUGCAGGUAG
				hsa-miR-302a	UAAGUGCUUCCAUGUUUUGGUGA
				hsa-miR-302b	UAAGUGCUUCCAUGUUUUAGUAG
				hsa-miR-302c	UAAGUGCUUCCAUGUUUCAGUGG
				hsa-miR-302d	UAAGUGCUUCCAUGUUUGAGUGU
				hsa-miR-372	AAAGUGCUGCGACAUUUGAGCGU
				hsa-miR-373	GAAGUGCUUCGAUUUUGGGGUGU
				hsa-miR-520e	AAAGUGCUUCCUUUUUGAGGG
				hsa-miR-520a	AAAGUGCUUCCCUUUGGACUGU
				hsa-miR-520b	AAAGUGCUUCCUUUUAGAGGG
				hsa-miR-520c	AAAGUGCUUCCUUUUAGAGGGUU
				hsa-miR-520d	AAAGUGCUUCUCUUUGGUGGGUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.

Gene Page: SMAD2