Search results: The pahtway p2986 has 206 genes in the original annotation. Currently, there are 118 genes in SZGR 2.0 (with evidence in schizophrenia) that are present at this pathway.

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Gene ID Symbol Synonyms Official Full Name Location SZ group ? Functional group ?
3688ITGB1CD29 | FNRB | GPIIA | MDF2 | MSK12 | VLA-BETA | VLABintegrin subunit beta 110p11.2CV:GWASdb
CV:PGCnp
GO_Annotation
Network
22931RAB18RAB18LI1 | WARBM3RAB18, member RAS oncogene family10p12.1CV:PGCnp
DMG:vanEijk_2014
PMID:cooccur
INTRACELLULAR TRAFFICKING
5464PPA1HEL-S-66p | IOPPP | PP | PP1 | SID6-8061pyrophosphatase (inorganic) 110q22.1CV:PGCnp
DMG:Jaffe_2016
DMG:Nishioka_2013
5954RCN1HEL-S-84 | PIG20 | RCAL | RCNreticulocalbin 111p13CV:PGCnp
2620GAS2-growth arrest specific 211p14.3CV:PGCnp
PMID:cooccur
1982EIF4G2AAG1 | DAP5 | NAT1 | P97eukaryotic translation initiation factor 4 gamma 211p15DMG:Jaffe_2016CompositeSet
Darnell FMRP targets
63875MRPL17L17mt | LIP2 | MRP-L17 | MRP-L26 | RPL17L | RPML26mitochondrial ribosomal protein L1711p15.5-p15.4CV:PGCnp
80789INTS5INT5 | KIAA1698integrator complex subunit 511q12.3CV:PGCnp
DNM:McCarthy_2014
10413YAP1COB1 | YAP | YAP2 | YAP65 | YKIYes associated protein 111q13CV:PGCnp
DMG:Jaffe_2016
DMG:Nishioka_2013
Expression
Network
2017CTTNEMS1cortactin11q13CV:PGCnp
DMG:Nishioka_2013
Network
CELL ADHESION AND TRANSSYNAPTIC SIGNALING
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
Ascano FMRP targets
Potential synaptic genes
595CCND1BCL1 | D11S287E | PRAD1 | U21B31cyclin D111q13DMG:Jaffe_2016
Network
PMID:cooccur
372ARCN1COPDarchain 111q23.3CV:PGCnp
GSMA_I
PMID:cooccur
84881RPUSD4-RNA pseudouridylate synthase domain containing 411q24.2CV:PGCnp
84897TBRG1NIAM | TB-5transforming growth factor beta regulator 111q24.2CV:PGCnp
3845KRASC-K-RAS | CFC2 | K-RAS2A | K-RAS2B | K-RAS4A | K-RAS4B | KI-RAS | KRAS1 | KRAS2 | NS | NS3 | RALD | RASK2Kirsten rat sarcoma viral oncogene homolog12p12.1CV:PGCnp
DMG:Nishioka_2013
GO_Annotation
Network
PMID:cooccur
CANABINOID
DOPAMINE
INTRACELLULAR SIGNAL TRANSDUCTION
METABOTROPIC GLUTAMATE RECEPTOR
SEROTONIN
G2Cdb.humanPSP
CompositeSet
50813COPS7ACSN7 | CSN7A | SGN7aCOP9 signalosome subunit 7A12p13.31CV:PGCnp
PMID:cooccur
8835SOCS2CIS2 | Cish2 | SOCS-2 | SSI-2 | SSI2 | STATI2suppressor of cytokine signaling 212qCV:PGCnp
PMID:cooccur
51474LIMA1EPLIN | SREBP3LIM domain and actin binding 112q13CV:PGCnp
DMG:Wockner_2014
11260XPOTXPO3exportin for tRNA12q14.2CV:PGCnp
DNM:Fromer_2014
CompositeSet
64786TBC1D15RAB7-GAPTBC1 domain family member 1512q21.1CV:GWASdb
CV:PGCnp
7296TXNRD1GRIM-12 | TR | TR1 | TRXR1 | TXNRthioredoxin reductase 112q23.3CV:PGCnp
121053C12orf45-chromosome 12 open reading frame 4512q23.3CV:PGCnp
DMG:Jaffe_2016
8099CDK2AP1DOC1 | DORC1 | ST19 | doc-1 | p12DOC-1cyclin-dependent kinase 2 associated protein 112q24.31CV:PGCnp
LK:YES
PMID:cooccur
65117RSRC2-arginine/serine-rich coiled-coil 212q24.31CV:PGCnp
10240MRPS31IMOGN38 | MRP-S31 | S31mtmitochondrial ribosomal protein S3113q14.11DMG:Jaffe_2016
DMG:vanEijk_2014
DMG:Wockner_2014
7174TPP2TPP-2 | TPPIItripeptidyl peptidase II13q32-q33CV:PGCnp
GO_Annotation
Ascano FMRP targets
51077FCF1Bka | C14orf111 | CGI-35 | UTP24FCF1 rRNA-processing protein14q24.3CV:PGCnp
Expression
79882ZC3H14MSUT-2 | NY-REN-37 | SUT2 | UKp68zinc finger CCCH-type containing 1414q31.3CV:PGCnp
DMG:Wockner_2014
23405DICER1DCR1 | Dicer | Dicer1e | HERNA | K12H4.8-LIKE | MNG1 | RMSE2dicer 1 ribonuclease III14q32.13CV:PGCnp
DEG:Sanders_2013
DMG:Wockner_2014
DNM:Fromer_2014
PMID:cooccur
CompositeSet
Darnell FMRP targets
7082TJP1ZO-1tight junction protein 115q13CV:GWAScat
CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
GO_Annotation
PMID:cooccur
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
54893MTMR10-myotubularin related protein 1015q13.3CNV:YES
CV:PGCnp
8669EIF3JEIF3S1 | eIF3-alpha | eIF3-p35eukaryotic translation initiation factor 3 subunit J15q21.1CV:PGCnp
DMG:Jaffe_2016
54700RRN3A-270G1.2 | TIFIARRN3 homolog, RNA polymerase I transcription factor16p12CV:PGCnp
GSMA_IIE
4706NDUFAB1ACP | FASN2A | SDAPNADH:ubiquinone oxidoreductase subunit AB116p12.2CV:PGCnp
Expression
GSMA_IIE
PMID:cooccur
9057SLC7A6LAT-2 | LAT3 | y+LAT-2solute carrier family 7 member 616q22.1CV:PGCnp
DMG:Nishioka_2013
DNM:Fromer_2014
CompositeSet
9100USP10UBPOubiquitin specific peptidase 1016q24.1CV:PGCnp
DNM:Guipponi_2014
9196KCNAB3AKR6A9 | KCNA3.1B | KCNA3B | KV-BETA-3potassium voltage-gated channel subfamily A regulatory beta subunit 317p13.1CV:PGCnp
DEG:Zhao_2015
DMG:Jaffe_2016
5717PSMD11Rpn6 | S9 | p44.5proteasome 26S subunit, non-ATPase 1117q11.2CV:PGCnp
10040TOM1L1OK/KNS-CL.3 | SRCASMtarget of myb1 like 1 membrane trafficking protein17q23.2CV:PGCnp
5635PRPSAP1PAP39phosphoribosyl pyrophosphate synthetase-associated protein 117q24-q25CV:PGCnp
DMG:Jaffe_2016
55250ELP2SHINC-2 | STATIP1 | StIPelongator acetyltransferase complex subunit 218q12.2CV:PGCnp
4087SMAD2JV18 | JV18-1 | MADH2 | MADR2 | hMAD-2 | hSMAD2SMAD family member 218q21.1CV:PGCnp
Network
PMID:cooccur
8463TEAD2ETF | TEAD-2 | TEF-4 | TEF4TEA domain transcription factor 219q13.3DMG:Wockner_2014
6814STXBP3MUNC18-3 | MUNC18C | PSP | UNC-18Csyntaxin binding protein 31p13.3DMG:Jaffe_2016CANABINOID
DOPAMINE
EXOCYTOSIS
METABOTROPIC GLUTAMATE RECEPTOR
SEROTONIN
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
CompositeSet
51611DPH5AD-018 | CGI-30 | HSPC143 | NPD015diphthamide biosynthesis 51p21.2CV:PGCnp
DMG:Nishioka_2013
2730GCLMGLCLRglutamate-cysteine ligase modifier subunit1p22.1Association
CV:PGCnp
GO_Annotation
GR_WM
PMID:cooccur
84146ZNF644BM-005 | MYP21 | NatF | ZEP-2zinc finger protein 6441p22.2CV:PGCnp
DMG:Nishioka_2013
34ACADMACAD1 | MCAD | MCADHacyl-CoA dehydrogenase, C-4 to C-12 straight chain1p31CV:PGCnp
GSMA_IIA
5876RABGGTBGGTBRab geranylgeranyltransferase beta subunit1p31CV:PGCnp
DEG:Maycox_2009
GSMA_IIA
26009ZZZ3ATAC1zinc finger ZZ-type containing 31p31.1CV:PGCnp
GSMA_IIA
9202ZMYM4CDIR | MYM | ZNF198L3 | ZNF262zinc finger MYM-type containing 41p32-p34CV:PGCnp
CV:PheWAS
2782GNB1-G protein subunit beta 11p36.33CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
Network
CANABINOID
DOPAMINE
G-PROTEIN RELAY
METABOTROPIC GLUTAMATE RECEPTOR
SEROTONIN
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_clathrin
G2Cdb.human_Synaptosome
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Darnell FMRP targets
2058EPRSEARS | GLUPRORS | PARS | PIG32 | QARS | QPRSglutamyl-prolyl-tRNA synthetase1q41GO_Annotation
Network
PMID:cooccur
CompositeSet
Ascano FMRP targets
10528NOP56NOL5A | SCA36NOP56 ribonucleoprotein20p13CV:PGCnp
60436TGIF2-TGFB induced factor homeobox 220q11.23CV:PGCnp
DMG:Wockner_2014
6431SRSF6B52 | HEL-S-91 | SFRS6 | SRP55serine/arginine-rich splicing factor 620q12-q13.1CV:PGCnp
Expression
7529YWHABGW128 | HEL-S-1 | HS1 | KCIP-1 | YWHAAtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta20q13.1CV:PGCnp
DMG:Wockner_2014
Network
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_clathrin
G2Cdb.human_mGluR5
G2Cdb.human_Synaptosome
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
571BACH1BACH-1 | BTBD24BTB and CNC homology 1, basic leucine zipper transcription factor 121q22.11CV:PGCnp
DMG:Jaffe_2016
874CBR3HEL-S-25 | SDR21C2 | hCBR3carbonyl reductase 321q22.2CV:PGCnpCompositeSet
7533YWHAHYWHA1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta22q12.3Association
CV:PGCnp
GO_Annotation
GR_Ng
GR_WM
GSMA_I
Network
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
G2Cdb.human_mGluR5
G2Cdb.humanNRC
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
Potential synaptic genes
8398PLA2G6CaI-PLA2 | GVI | INAD1 | IPLA2-VIA | NBIA2 | NBIA2A | NBIA2B | PARK14 | PLA2 | PNPLA9 | iPLA2 | iPLA2betaphospholipase A2 group VI22q13.1Association
CV:PGCnp
GR_Ng
GR_WM
PMID:cooccur
10199MPHOSPH10CT90 | MPP10 | MPP10P | PPP1R106M-phase phosphoprotein 102p13.3CV:PGCnp
DMG:Jaffe_2016
7514XPO1CRM1 | emb | exp1exportin 12p15CV:PGCnp
DMG:Jaffe_2016
790CADCDG1Zcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase2p22-p21CV:PGCnp
GO_Annotation
Network
PMID:cooccur
Ascano FMRP targets
9475ROCK2ROCK-IIRho associated coiled-coil containing protein kinase 22p24CV:PGCnp
PMID:cooccur
INTRACELLULAR SIGNAL TRANSDUCTION
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.humanPSD
G2Cdb.humanPSP
CompositeSet
10190TXNDC9APACD | PHLP3thioredoxin domain containing 92q11.2CV:PGCnp
DMG:Jaffe_2016
DMG:Nishioka_2013
Expression
GSMA_I
64844MARCH7AXO | AXOT | MARCH-VII | RNF177membrane associated ring-CH-type finger 72q24.2CV:PGCnp
GSMA_IIA
3655ITGA6CD49f | ITGA6B | VLA-6integrin subunit alpha 62q31.1CV:PGCnp
DMG:Nishioka_2013
DNM:Ambalavanan_2016
DNM:Xu_2012
Expression
PMID:cooccur
CompositeSet
57703CWC22EIF4GL | NCM | fSAPbCWC22 homolog, spliceosome-associated protein2q31.3CV:PGCnpAscano FMRP targets
1841DTYMKCDC8 | PP3731 | TMPK | TYMKdeoxythymidylate kinase2q37.3CV:PGCnp
DMG:Jaffe_2016
8801SUCLG2GBETAsuccinate-CoA ligase, GDP-forming, beta subunit3p14.1CV:PGCnp
11102RPP14HsHTD2 | P14ribonuclease P/MRP 14kDa subunit3p14.3CV:PGCnp
9497SLC4A7NBC2 | NBC3 | NBCN1 | SBC2 | SLC4A6solute carrier family 4 member 73p22CV:PGCnp
GO_Annotation
GSMA_I
10491CRTAPCASP | LEPREL3 | OI7 | P3H5cartilage associated protein3p22.3CV:PGCnp
DMG:Jaffe_2016
GSMA_I
84522JAGN1GL009 | SCN6jagunal homolog 13p25.2CV:GWASdb
CV:PGCnp
DEG:Zhao_2015
7372UMPSOPRTuridine monophosphate synthetase3q13CV:PGCnp
DMG:Jaffe_2016
DMG:Wockner_2014
116064LRRC58-leucine rich repeat containing 583q13.33CV:PGCnp
DMG:Jaffe_2016
11222MRPL3COXPD9 | MRL3 | RPML3mitochondrial ribosomal protein L33q21-q23CV:PGCnp
5504PPP1R2IPP-2 | IPP2protein phosphatase 1 regulatory inhibitor subunit 23q29CV:PGCnp
PMID:cooccur
54965PIGXPIG-Xphosphatidylinositol glycan anchor biosynthesis class X3q29CNV:YES
CV:PGCnp
133015PACRGLC4orf28PARK2 co-regulated like4p15.31CV:GWASdb
CV:PGCnp
26057ANKRD17GTAR | MASK2 | NY-BR-16ankyrin repeat domain 174q13.3CV:PGCnpCompositeSet
Darnell FMRP targets
51138COPS4CSN4COP9 signalosome subunit 44q21.22CV:PGCnp
DMG:Wockner_2014
5311PKD2APKD2 | PC2 | PKD4 | Pc-2 | TRPP2polycystin 2, transient receptor potential cation channel4q22.1CV:PGCnp
CV:PheWAS
56916SMARCAD1ADERM | ETL1 | HEL1SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 14q22.3CV:GWAScat
CV:GWASdb
CV:PGCnp
PMID:cooccur
79071ELOVL6FACE | FAE | LCEELOVL fatty acid elongase 64q25CV:GWASdb
CV:PGCnp
DEG:Sanders_2013
DMG:Jaffe_2016
DMG:Wockner_2014
4086SMAD1BSP-1 | BSP1 | JV4-1 | JV41 | MADH1 | MADR1SMAD family member 14q31CV:PGCnp
GO_Annotation
2549GAB1-GRB2 associated binding protein 14q31.21CV:PGCnp
152503SH3D19EBP | EVE1 | Kryn | SH3P19SH3 domain containing 194q31.3CV:GWASdb
CV:PGCnp
DMG:Wockner_2014
26269FBXO8DC10 | FBS | FBX8F-box protein 84q34.1CV:PGCnp
DMG:Nishioka_2013
2690GHRGHBP | GHIPgrowth hormone receptor5p13-p12CV:PGCnp
PMID:cooccur
3796KIF2ACDCBM3 | HK2 | KIF2kinesin heavy chain member 2A5q12-q13Association
CV:GWASdb
CV:PGCnp
DMG:Jaffe_2016
GO_Annotation
PMID:cooccur
STRUCTURAL PLASTICITY
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
CompositeSet
Potential synaptic genes
5921RASA1CM-AVM | CMAVM | GAP | PKWS | RASA | RASGAP | p120 | p120GAP | p120RASGAPRAS p21 protein activator 15q13.3CV:PGCnp
DMG:Jaffe_2016
GO_Annotation
Network
1105CHD1-chromodomain helicase DNA binding protein 15q15-q21CV:PGCnp
DMG:Jaffe_2016
5480PPICCYPCpeptidylprolyl isomerase C5q23.2CV:PGCnp
PMID:cooccur
501ALDH7A1ATQ1 | EPD | PDEaldehyde dehydrogenase 7 family member A15q31CV:PGCnp
DMG:Jaffe_2016
GSMA_I
CompositeSet
7322UBE2D2E2(17)KB2 | PUBC1 | UBC4 | UBC4/5 | UBCH4 | UBCH5Bubiquitin conjugating enzyme E2 D25q31.2CV:PGCnp
GSMA_I
54853WDR55-WD repeat domain 555q31.3CV:PGCnp
GSMA_I
153830RNF145-ring finger protein 1455q33.3CV:PGCnp
GSMA_I
GSMA_IIA
GSMA_IIE
705BYSLBYSTINbystin like6p21.1CV:PGCnp
DMG:Jaffe_2016
GSMA_I
GSMA_IIE
1026CDKN1ACAP20 | CDKN1 | CIP1 | MDA-6 | P21 | SDI1 | WAF1 | p21CIP1cyclin-dependent kinase inhibitor 1A6p21.2CV:PGCnp
DMG:Wockner_2014
GSMA_I
GSMA_IIE
Network
PMID:cooccur
57819LSM2C6orf28 | G7B | YBL026W | snRNPLSM2 homolog, U6 small nuclear RNA and mRNA degradation associated6p21.3CV:PGCnp
DMG:Wockner_2014
GSMA_I
Network
2739GLO1GLOD1 | GLYI | HEL-S-74glyoxalase I6p21.3-p21.1CV:PGCnp
DEG:Sanders_2013
GSMA_I
GSMA_IIE
PMID:cooccur
CELL METABOLISM
6631SNRPCU1C | Yhc1small nuclear ribonucleoprotein polypeptide C6p21.31CV:PGCnp
DMG:Nishioka_2013
GSMA_I
GSMA_IIE
29078NDUFAF4C6orf66 | HRPAP20 | HSPC125 | My013 | bA22L21.1NADH:ubiquinone oxidoreductase complex assembly factor 46q16.1CV:PGCnp
57038RARS2ArgRS | DALRD2 | PCH6 | PRO1992 | RARSLarginyl-tRNA synthetase 2, mitochondrial6q16.1CV:PGCnp
9439MED23ARC130 | CRSP130 | CRSP133 | CRSP3 | DRIP130 | MRT18 | SUR-2 | SUR2mediator complex subunit 236q22.33-q24.1CV:PGCnp
DMG:Jaffe_2016
39ACAT2-acetyl-CoA acetyltransferase 26q25.3CV:PGCnp
PMID:cooccur
11328FKBP9FKBP60 | FKBP63 | PPIaseFK506 binding protein 97p11.1CV:PGCnp
DMG:Wockner_2014
7205TRIP6OIP-1 | OIP1 | TRIP-6 | TRIP6i2 | ZRP-1thyroid hormone receptor interactor 67q22CV:PGCnp
Network
29969MDFICHICMyoD family inhibitor domain containing7q31.1-q31.2CV:PGCnp
PMID:cooccur
10049DNAJB6DJ4 | DnaJ | HHDJ1 | HSJ-2 | HSJ2 | LGMD1D | LGMD1E | MRJ | MSJ-1DnaJ heat shock protein family (Hsp40) member B67q36.3CV:PGCnp
DMG:Wockner_2014
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
CompositeSet
1978EIF4EBP14E-BP1 | 4EBP1 | BP-1 | PHAS-Ieukaryotic translation initiation factor 4E binding protein 18p12CV:PGCnp
DMG:Jaffe_2016
Network
10171RCL1RNAC | RPCL1RNA terminal phosphate cyclase-like 19p24.1-p23CV:GWASdb
CV:PGCnp
3376IARSIARS1 | ILERS | ILRS | IRS | PRO0785isoleucyl-tRNA synthetase9q21CV:PGCnp
5887RAD23BHHR23B | HR23B | P58RAD23 homolog B, nucleotide excision repair protein9q31.2CV:PGCnp
DMG:Jaffe_2016
51116MRPS2CGI-91 | MRP-S2 | S2mtmitochondrial ribosomal protein S29q34CV:PGCnp
DMG:Jaffe_2016
5358PLS3BMND18 | T-plastinplastin 3Xq23CV:PGCnp
DMG:Nishioka_2013