Gene Page: ATP6
Summary ?
| GeneID | 4508 |
| Symbol | ATP6 |
| Synonyms | ATPase6|MTATP6 |
| Description | ATP synthase F0 subunit 6 |
| Reference | MIM:516060|HGNC:HGNC:7414| |
| Gene type | protein-coding |
| Map location | - |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RFTN2 | 0.85 | 0.84 |
| PDLIM5 | 0.85 | 0.85 |
| SSFA2 | 0.83 | 0.85 |
| PLOD2 | 0.83 | 0.82 |
| KAT2B | 0.82 | 0.83 |
| ADD3 | 0.82 | 0.84 |
| QKI | 0.82 | 0.87 |
| SSPN | 0.82 | 0.77 |
| TOR1AIP1 | 0.81 | 0.81 |
| IRF2 | 0.80 | 0.80 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AC011491.1 | -0.37 | -0.40 |
| NANOS3 | -0.36 | -0.42 |
| RP9P | -0.35 | -0.44 |
| IER5L | -0.33 | -0.25 |
| STRA13 | -0.33 | -0.43 |
| C3orf54 | -0.33 | -0.33 |
| C1orf86 | -0.33 | -0.39 |
| NR2C2AP | -0.33 | -0.35 |
| AC174470.1 | -0.32 | -0.35 |
| BID | -0.31 | -0.35 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG OXIDATIVE PHOSPHORYLATION | 135 | 73 | All SZGR 2.0 genes in this pathway |
| KEGG ALZHEIMERS DISEASE | 169 | 110 | All SZGR 2.0 genes in this pathway |
| KEGG PARKINSONS DISEASE | 133 | 78 | All SZGR 2.0 genes in this pathway |
| KEGG HUNTINGTONS DISEASE | 185 | 109 | All SZGR 2.0 genes in this pathway |
| REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 141 | 85 | All SZGR 2.0 genes in this pathway |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 98 | 56 | All SZGR 2.0 genes in this pathway |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 9 | All SZGR 2.0 genes in this pathway |
| LIU BREAST CANCER | 30 | 19 | All SZGR 2.0 genes in this pathway |
| LEE AGING CEREBELLUM DN | 86 | 66 | All SZGR 2.0 genes in this pathway |
| ZAMORA NOS2 TARGETS DN | 96 | 71 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 2 UP | 140 | 94 | All SZGR 2.0 genes in this pathway |