Gene Page: MTTP

Summary ?
GeneID4547
SymbolMTTP
SynonymsABL|MTP
Descriptionmicrosomal triglyceride transfer protein
ReferenceMIM:157147|HGNC:HGNC:7467|Ensembl:ENSG00000138823|HPRD:01144|Vega:OTTHUMG00000131023
Gene typeprotein-coding
Map location4q24
Pascal p-value0.593
Fetal beta0.269
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17107208chr152884681MTTP45470.06trans
rs12060661chr1218238494MTTP45470trans
snp_a-18097640MTTP45470.12trans
rs10489958chr1221202661MTTP45470.14trans
rs10196529chr222475979MTTP45470.14trans
rs13409526chr222508913MTTP45470.14trans
rs12617962chr286513101MTTP45470.11trans
rs17023999chr2100951590MTTP45470.08trans
rs10168656chr2146923444MTTP45470.1trans
rs7608936chr2146933933MTTP45470.1trans
rs13387176chr2167403516MTTP45470trans
rs17613002chr2221571132MTTP45470.07trans
rs16861747chr2221643239MTTP45470.02trans
rs16861754chr2221643553MTTP45470.12trans
rs16861756chr2221643602MTTP45470.04trans
rs1510514chr2239436367MTTP45474.374E-4trans
rs179852chr3172328734MTTP45470.01trans
rs4544747chr4179527501MTTP45470.11trans
rs3911341chr533328176MTTP45470.2trans
rs7709525chr533333510MTTP45470.06trans
rs16896739chr566716605MTTP45470.04trans
rs6862696chr566724676MTTP45470.01trans
rs7734355chr5102747929MTTP45470.02trans
rs4958094chr5133001523MTTP45470.15trans
rs9378305chr61703289MTTP45470.18trans
rs9503011chr61704149MTTP45470.18trans
rs4052671chr624223578MTTP45470.13trans
rs17057213chr697459552MTTP45470.04trans
rs7748086chr697471138MTTP45470.04trans
rs6949211chr711231070MTTP45470.14trans
rs17160028chr731292738MTTP45470trans
rs920630chr826448752MTTP45470trans
rs17055486chr826449410MTTP45470trans
rs7001738chr826455799MTTP45470.05trans
rs17782229chr833937315MTTP45470.03trans
rs2513956chr898838200MTTP45470.08trans
snp_a-18389410MTTP45470.06trans
snp_a-18220680MTTP45470.15trans
rs538066chr9130494956MTTP45470.12trans
rs17093688chr9137170563MTTP45470.06trans
rs16924738chr1024712202MTTP45470.19trans
rs11005510chr1058532988MTTP45470.01trans
rs16909905chr1058740538MTTP45470.15trans
rs17099339chr1083832303MTTP45470.18trans
rs540477chr10100315774MTTP45470.01trans
rs628037chr10100325514MTTP45470.03trans
rs1381549chr10100332800MTTP45470.03trans
rs10736134chr10100344123MTTP45470.1trans
rs3866908chr10100347967MTTP45470.07trans
rs675410chr10100350321MTTP45470.03trans
rs12244614chr10100353615MTTP45470.03trans
rs12294434chr1112265082MTTP45470.03trans
rs2283252chr1117520964MTTP45470.11trans
rs7941111chr11112562626MTTP45470.1trans
rs7953173chr1244488755MTTP45470.05trans
rs17042851chr1277469962MTTP45471.599E-4trans
rs10732643chr1289162114MTTP45470.06trans
rs12309615chr1298585947MTTP45470.05trans
rs7304029chr12120295224MTTP45470.07trans
rs7988137chr1320682078MTTP45470.16trans
rs2313862chr1320933817MTTP45470trans
rs3961328chr1325516431MTTP45470.1trans
rs954547chr1341039976MTTP45470.11trans
rs2137842chr1361344861MTTP45470.05trans
rs17750196chr1529741278MTTP45470.06trans
rs882396chr1537194830MTTP45470.1trans
rs2415151chr1573723264MTTP45470.02trans
rs17650617chr1593867698MTTP45470.08trans
rs2240690chr162026441MTTP45470.16trans
rs9946000chr1844296318MTTP45470trans
rs16940060chr1844348819MTTP45470trans
rs6133799chr2010086798MTTP45470.12trans
rs12556858chrX93352570MTTP45470.02trans
rs12556892chrX93417735MTTP45470trans
rs808754chrX93438033MTTP45470trans
rs5930726chrX134658726MTTP45470.13trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS 478302All SZGR 2.0 genes in this pathway
REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT 4637All SZGR 2.0 genes in this pathway
REACTOME LIPOPROTEIN METABOLISM 2824All SZGR 2.0 genes in this pathway
REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT 1615All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367220All SZGR 2.0 genes in this pathway
SANSOM APC TARGETS DN 366238All SZGR 2.0 genes in this pathway
HSIAO LIVER SPECIFIC GENES 244154All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN 274165All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS UP 9356All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN 17997All SZGR 2.0 genes in this pathway
WOO LIVER CANCER RECURRENCE DN 8054All SZGR 2.0 genes in this pathway
OHGUCHI LIVER HNF4A TARGETS DN 14985All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549316All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682433All SZGR 2.0 genes in this pathway