Gene Page: FAM178B
Summary ?
| GeneID | 51252 |
| Symbol | FAM178B |
| Synonyms | - |
| Description | family with sequence similarity 178 member B |
| Reference | HGNC:HGNC:28036|Ensembl:ENSG00000168754|HPRD:14235|Vega:OTTHUMG00000155257 |
| Gene type | protein-coding |
| Map location | 2q11.2 |
| Pascal p-value | 1.335E-4 |
| eGene | Cortex Frontal Cortex BA9 Putamen basal ganglia Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs62152901 | 2 | 97564898 | FAM178B | ENSG00000168754.9 | 8.702E-6 | 0.02 | 119277 | gtex_brain_putamen_basal |
| rs7589232 | 2 | 97566148 | FAM178B | ENSG00000168754.9 | 9.316E-6 | 0.02 | 118027 | gtex_brain_putamen_basal |
| rs6721921 | 2 | 97566501 | FAM178B | ENSG00000168754.9 | 9.328E-6 | 0.02 | 117674 | gtex_brain_putamen_basal |
| rs59131346 | 2 | 97566768 | FAM178B | ENSG00000168754.9 | 9.328E-6 | 0.02 | 117407 | gtex_brain_putamen_basal |
| rs140006341 | 2 | 97568771 | FAM178B | ENSG00000168754.9 | 9.106E-6 | 0.02 | 115404 | gtex_brain_putamen_basal |
| rs4260285 | 2 | 97570081 | FAM178B | ENSG00000168754.9 | 9.106E-6 | 0.02 | 114094 | gtex_brain_putamen_basal |
| rs62152904 | 2 | 97571873 | FAM178B | ENSG00000168754.9 | 9.396E-6 | 0.02 | 112302 | gtex_brain_putamen_basal |
| rs140933337 | 2 | 97572551 | FAM178B | ENSG00000168754.9 | 9.69E-6 | 0.02 | 111624 | gtex_brain_putamen_basal |
| rs10191663 | 2 | 97573844 | FAM178B | ENSG00000168754.9 | 5.924E-6 | 0.02 | 110331 | gtex_brain_putamen_basal |
| rs62152910 | 2 | 97577082 | FAM178B | ENSG00000168754.9 | 6.353E-6 | 0.02 | 107093 | gtex_brain_putamen_basal |
| rs6734673 | 2 | 97577241 | FAM178B | ENSG00000168754.9 | 6.147E-6 | 0.02 | 106934 | gtex_brain_putamen_basal |
| rs6717064 | 2 | 97577343 | FAM178B | ENSG00000168754.9 | 3.762E-6 | 0.02 | 106832 | gtex_brain_putamen_basal |
| rs17119655 | 2 | 97577495 | FAM178B | ENSG00000168754.9 | 5.862E-6 | 0.02 | 106680 | gtex_brain_putamen_basal |
| rs13390019 | 2 | 97797680 | FAM178B | ENSG00000168754.9 | 6.533E-6 | 0.02 | -113505 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DARWICHE SKIN TUMOR PROMOTER DN | 185 | 115 | All SZGR 2.0 genes in this pathway |
| DARWICHE PAPILLOMA RISK LOW DN | 165 | 107 | All SZGR 2.0 genes in this pathway |
| DARWICHE PAPILLOMA RISK HIGH DN | 180 | 110 | All SZGR 2.0 genes in this pathway |
| DARWICHE SQUAMOUS CELL CARCINOMA DN | 181 | 107 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS LATE PROGENITOR | 544 | 307 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 1 | 528 | 324 | All SZGR 2.0 genes in this pathway |
| ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF HCP WITH H3 UNMETHYLATED | 228 | 119 | All SZGR 2.0 genes in this pathway |