Gene Page: GPR88

Summary ?
GeneID54112
SymbolGPR88
SynonymsSTRG
DescriptionG protein-coupled receptor 88
ReferenceMIM:607468|HGNC:HGNC:4539|Ensembl:ENSG00000181656|HPRD:16248|Vega:OTTHUMG00000010981
Gene typeprotein-coding
Map location1p21.3
Pascal p-value0.698
Sherlock p-value0.159
Fetal beta-1.827
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10492950chr16006571GPR88541120.07trans
rs596985chr164277034GPR88541120.11trans
rs16838771chr1157511227GPR88541121.32E-10trans
rs17601631chr1169800689GPR88541120.15trans
rs6713473chr211284414GPR88541120.01trans
rs17019687chr280972176GPR88541120trans
rs17028172chr2103608895GPR88541124.597E-4trans
rs195315chr2109673132GPR88541120.07trans
rs16823058chr2170317903GPR88541120.01trans
rs16865055chr2224523383GPR88541120.14trans
snp_a-42335200GPR88541120.18trans
rs1344868chr321311149GPR88541120.04trans
snp_a-42334650GPR88541120trans
rs1587651chr379944075GPR88541120.05trans
rs6780018chr381405814GPR88541120trans
rs12637719chr385328350GPR88541120.15trans
rs9310002chr386223414GPR88541120.03trans
rs7642170chr386251251GPR88541120.03trans
rs10937395chr3189336369GPR88541120.04trans
rs6819929chr442511311GPR88541120.01trans
rs3025740chr4114163593GPR88541120.09trans
rs17011450chr4127630275GPR88541120.15trans
rs11098889chr4127631087GPR88541120.15trans
rs1491136chr4127646153GPR88541120.1trans
rs1491137chr4127646180GPR88541120.1trans
rs4277734chr4156916543GPR88541123.259E-4trans
rs1922648chr4160458423GPR88541120.16trans
rs7718330chr516023311GPR88541120.02trans
rs491989chr531452998GPR88541120.03trans
rs35406chr533946142GPR88541120.01trans
rs17186508chr565194022GPR88541120.03trans
rs7448080chr5123398097GPR88541120.14trans
rs17165234chr5126403634GPR88541120.01trans
rs1194997chr5146093747GPR88541120.13trans
rs7453019chr625457856GPR88541120.1trans
rs283063chr6118621313GPR88541120.01trans
rs4642501chr6148696792GPR88541120.01trans
rs9397728chr6150514248GPR88541121.328E-5trans
rs4320477chr7115490675GPR88541120.11trans
rs11978687chr7136765689GPR88541120.17trans
rs881927chr7155973732GPR88541120.13trans
rs16909591chr8139787216GPR88541120.11trans
rs2066315chr10514137GPR88541120.01trans
rs17143455chr108368252GPR88541120.02trans
rs16922710chr1023087297GPR88541125.435E-4trans
rs16922725chr1023100286GPR88541120.18trans
rs10508654chr1023104638GPR88541122.023E-4trans
rs16922768chr1023162329GPR88541120.14trans
rs10786907chr1083908248GPR88541120.07trans
rs7081986chr1090807242GPR88541120.05trans
rs2296217chr10105780134GPR88541120.12trans
rs11018189chr10129345787GPR88541120.01trans
rs1783466chr1156650948GPR88541120.19trans
rs11224488chr11100723105GPR88541120.18trans
rs12580163chr122134197GPR88541120.01trans
rs4764219chr1215812187GPR88541120.19trans
rs11178165chr1270669547GPR88541120.11trans
rs11178166chr1270670585GPR88541122.545E-4trans
rs12301144chr12108825968GPR88541120.06trans
rs7303847chr12115691634GPR88541120.13trans
rs4943464chr1337838293GPR88541120.14trans
rs7982899chr1337839250GPR88541120.14trans
rs575555chr1352437620GPR88541120.15trans
rs16967008chr13106287437GPR88541120trans
rs17104965chr1437145915GPR88541120.04trans
rs10047895chr1457512171GPR88541120.07trans
rs362341chr1473641457GPR88541120.18trans
rs284907chr1576741568GPR88541120.04trans
rs284904chr1576744301GPR88541120.12trans
rs284898chr1576750694GPR88541120.11trans
rs7171135chr1586479875GPR88541120.01trans
rs4497712chr1611800767GPR88541120.17trans
rs4781412chr1613203337GPR88541120.06trans
rs443222chr1683889679GPR88541122.479E-6trans
rs824575chr1683891459GPR88541122.479E-6trans
rs11081028chr183269332GPR88541122.78E-4trans
rs1703838chr1833116125GPR88541120trans
rs6120222chr2031890174GPR88541120.02trans
rs11086177chr2045350682GPR88541120.19trans
rs2835891chr2139056226GPR88541121.275E-5trans
rs6519257chr2241889401GPR88541120.18trans
rs1883665chrX17650382GPR88541123.005E-8trans
rs7062071chrX17724830GPR88541122.755E-4trans
rs16989685chrX31527328GPR88541120.08trans
rs5974674chrX136410712GPR88541120.03trans
rs7879274chrX145592957GPR88541122.852E-4trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
RODRIGUES DCC TARGETS DN 12184All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652441All SZGR 2.0 genes in this pathway
ZHAN MULTIPLE MYELOMA CD1 AND CD2 UP 8951All SZGR 2.0 genes in this pathway
KANG IMMORTALIZED BY TERT DN 10267All SZGR 2.0 genes in this pathway
KONDO PROSTATE CANCER WITH H3K27ME3 19693All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354216All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 142103All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069729All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 DN 170105All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS POLYSOMY7 UP 7950All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA DN 267160All SZGR 2.0 genes in this pathway
MIKKELSEN NPC HCP WITH H3K4ME3 AND H3K27ME3 210148All SZGR 2.0 genes in this pathway