Summary ?
GeneID5506
SymbolPPP1R3A
SynonymsGM|PP1G|PPP1R3
Descriptionprotein phosphatase 1 regulatory subunit 3A
ReferenceMIM:600917|HGNC:HGNC:9291|Ensembl:ENSG00000154415|HPRD:02950|Vega:OTTHUMG00000156944
Gene typeprotein-coding
Map location7q31.1
Pascal p-value0.024

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
PEX190.900.90
GDE10.880.88
GHITM0.860.89
HCCS0.860.86
MAT2B0.860.88
ATG70.850.88
TMX20.850.87
PGK10.850.84
PKM20.850.88
ARL8B0.850.89
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AC010300.1-0.45-0.47
AC005921.3-0.45-0.55
AC135724.1-0.43-0.49
RP9P-0.42-0.46
FAM159B-0.41-0.47
ZNF814-0.41-0.49
IL3RA-0.41-0.56
AF347015.18-0.41-0.16
AL022328.1-0.40-0.42
C10orf108-0.38-0.35

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG INSULIN SIGNALING PATHWAY 137103All SZGR 2.0 genes in this pathway
PID INSULIN GLUCOSE PATHWAY 2624All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 SIGNATURE 3 UP 341197All SZGR 2.0 genes in this pathway
SWEET KRAS TARGETS DN 6639All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE DN 261183All SZGR 2.0 genes in this pathway
XU GH1 EXOGENOUS TARGETS DN 12069All SZGR 2.0 genes in this pathway
MOOTHA GLYCOGEN METABOLISM 2116All SZGR 2.0 genes in this pathway
PURBEY TARGETS OF CTBP1 NOT SATB1 DN 448282All SZGR 2.0 genes in this pathway