Gene Page: ALPK3
Summary ?
| GeneID | 57538 |
| Symbol | ALPK3 |
| Synonyms | MAK|MIDORI |
| Description | alpha kinase 3 |
| Reference | HGNC:HGNC:17574|Ensembl:ENSG00000136383|HPRD:11365|Vega:OTTHUMG00000148667 |
| Gene type | protein-coding |
| Map location | 15q25.2 |
| Pascal p-value | 5.714E-7 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| SDR39U1 | 0.87 | 0.84 |
| COQ4 | 0.87 | 0.86 |
| RHBDD3 | 0.86 | 0.87 |
| TMUB1 | 0.86 | 0.85 |
| PEMT | 0.86 | 0.86 |
| C22orf36 | 0.85 | 0.85 |
| TSSC4 | 0.85 | 0.83 |
| ADCK4 | 0.85 | 0.85 |
| VPS28 | 0.85 | 0.82 |
| GPR175 | 0.84 | 0.82 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.27 | -0.52 | -0.55 |
| AF347015.8 | -0.52 | -0.56 |
| AF347015.31 | -0.51 | -0.54 |
| MT-CYB | -0.51 | -0.55 |
| MT-CO2 | -0.50 | -0.53 |
| MT-ATP8 | -0.50 | -0.63 |
| AF347015.33 | -0.50 | -0.53 |
| AF347015.2 | -0.49 | -0.55 |
| AF347015.15 | -0.48 | -0.53 |
| AF347015.26 | -0.47 | -0.54 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
| LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
| PENG LEUCINE DEPRIVATION UP | 142 | 93 | All SZGR 2.0 genes in this pathway |
| KUROKAWA LIVER CANCER CHEMOTHERAPY UP | 12 | 8 | All SZGR 2.0 genes in this pathway |
| MANALO HYPOXIA UP | 207 | 145 | All SZGR 2.0 genes in this pathway |
| REN ALVEOLAR RHABDOMYOSARCOMA UP | 98 | 64 | All SZGR 2.0 genes in this pathway |
| KAAB HEART ATRIUM VS VENTRICLE DN | 261 | 183 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR DN | 88 | 59 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP B | 549 | 316 | All SZGR 2.0 genes in this pathway |
| VANDESLUIS COMMD1 TARGETS GROUP 3 UP | 89 | 50 | All SZGR 2.0 genes in this pathway |