SZGR2

Summary ?

GeneID	635
Symbol	BHMT
Synonyms	BHMT1\|HEL-S-61p
Description	betaine--homocysteine S-methyltransferase
Reference	MIM:602888\|HGNC:HGNC:1047\|Ensembl:ENSG00000145692\|HPRD:04200\|Vega:OTTHUMG00000108157
Gene type	protein-coding
Map location	5q14.1
Pascal p-value	0.033
eGene	Caudate basal ganglia Cortex Hippocampus Meta

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	Click to show details

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AC021087.1	0.53	0.28
GSX1	0.51	0.19
C1QL4	0.51	0.12
PRSS36	0.51	0.25
PROK2	0.50	0.25
PRG2	0.50	0.14
SLC5A10	0.49	0.20
KISS1R	0.48	0.15
C3orf45	0.47	0.19
MTL5	0.46	0.10

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
COX4I2	-0.22	-0.29
C5orf53	-0.22	-0.26
MT-CO2	-0.21	-0.27
AF347015.31	-0.21	-0.28
AF347015.33	-0.20	-0.26
MOBP	-0.20	-0.24
AF347015.27	-0.20	-0.27
MT-CYB	-0.20	-0.27
MBP	-0.19	-0.22
GBP2	-0.18	-0.22

Section V. Pathway annotation