Gene Page: SULT1A2
Summary ?
| GeneID | 6799 |
| Symbol | SULT1A2 |
| Synonyms | HAST4|P-PST|ST1A2|STP2|TSPST2 |
| Description | sulfotransferase family 1A member 2 |
| Reference | MIM:601292|HGNC:HGNC:11454|Ensembl:ENSG00000197165|HPRD:03187|Vega:OTTHUMG00000048082 |
| Gene type | protein-coding |
| Map location | 16p12.1 |
| Pascal p-value | 0.14 |
| Sherlock p-value | 0.003 |
| Fetal beta | -0.701 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellum Cortex Hippocampus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_IIE | Genome scan meta-analysis (European-ancestry samples) | Psr: 0.01775 | |
| GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6861033 | chr5 | 34917845 | SULT1A2 | 6799 | 0.03 | trans | ||
| rs11134797 | chr5 | 172860595 | SULT1A2 | 6799 | 0.02 | trans | ||
| rs3823429 | chr6 | 38864060 | SULT1A2 | 6799 | 0.17 | trans | ||
| rs9650652 | chr8 | 10267591 | SULT1A2 | 6799 | 0.1 | trans | ||
| rs6601456 | chr8 | 10275121 | SULT1A2 | 6799 | 0.1 | trans | ||
| rs6512744 | chr20 | 50305594 | SULT1A2 | 6799 | 0.1 | trans | ||
| rs62034276 | 16 | 28473465 | SULT1A2 | ENSG00000197165.6 | 4.218E-6 | 0.01 | 134965 | gtex_brain_ba24 |
| rs3785354 | 16 | 28550667 | SULT1A2 | ENSG00000197165.6 | 3.069E-6 | 0.01 | 57763 | gtex_brain_ba24 |
| rs4787457 | 16 | 28555400 | SULT1A2 | ENSG00000197165.6 | 3.045E-6 | 0.01 | 53030 | gtex_brain_ba24 |
| rs4788080 | 16 | 28558081 | SULT1A2 | ENSG00000197165.6 | 3.142E-6 | 0.01 | 50349 | gtex_brain_ba24 |
| rs4788079 | 16 | 28559363 | SULT1A2 | ENSG00000197165.6 | 3.439E-6 | 0.01 | 49067 | gtex_brain_ba24 |
| rs4787456 | 16 | 28559573 | SULT1A2 | ENSG00000197165.6 | 3.045E-6 | 0.01 | 48857 | gtex_brain_ba24 |
| rs4788078 | 16 | 28559981 | SULT1A2 | ENSG00000197165.6 | 3.045E-6 | 0.01 | 48449 | gtex_brain_ba24 |
| rs62034350 | 16 | 28562256 | SULT1A2 | ENSG00000197165.6 | 3.021E-6 | 0.01 | 46174 | gtex_brain_ba24 |
| rs7187604 | 16 | 28565953 | SULT1A2 | ENSG00000197165.6 | 3.451E-6 | 0.01 | 42477 | gtex_brain_ba24 |
| rs4788076 | 16 | 28570005 | SULT1A2 | ENSG00000197165.6 | 3.045E-6 | 0.01 | 38425 | gtex_brain_ba24 |
| rs370527719 | 16 | 28570703 | SULT1A2 | ENSG00000197165.6 | 2.947E-6 | 0.01 | 37727 | gtex_brain_ba24 |
| rs56396270 | 16 | 28580829 | SULT1A2 | ENSG00000197165.6 | 3.036E-6 | 0.01 | 27601 | gtex_brain_ba24 |
| rs12447461 | 16 | 28582941 | SULT1A2 | ENSG00000197165.6 | 3.036E-6 | 0.01 | 25489 | gtex_brain_ba24 |
| rs112191041 | 16 | 28583362 | SULT1A2 | ENSG00000197165.6 | 3.038E-6 | 0.01 | 25068 | gtex_brain_ba24 |
| rs111693583 | 16 | 28583610 | SULT1A2 | ENSG00000197165.6 | 3.038E-6 | 0.01 | 24820 | gtex_brain_ba24 |
| rs11074911 | 16 | 28583865 | SULT1A2 | ENSG00000197165.6 | 3.038E-6 | 0.01 | 24565 | gtex_brain_ba24 |
| rs56209193 | 16 | 28585636 | SULT1A2 | ENSG00000197165.6 | 2.956E-6 | 0.01 | 22794 | gtex_brain_ba24 |
| rs7193402 | 16 | 28586127 | SULT1A2 | ENSG00000197165.6 | 3.039E-6 | 0.01 | 22303 | gtex_brain_ba24 |
| rs7186573 | 16 | 28587389 | SULT1A2 | ENSG00000197165.6 | 2.89E-6 | 0.01 | 21041 | gtex_brain_ba24 |
| rs62034358 | 16 | 28587597 | SULT1A2 | ENSG00000197165.6 | 3.04E-6 | 0.01 | 20833 | gtex_brain_ba24 |
| rs12445823 | 16 | 28588049 | SULT1A2 | ENSG00000197165.6 | 3.041E-6 | 0.01 | 20381 | gtex_brain_ba24 |
| rs12445744 | 16 | 28588395 | SULT1A2 | ENSG00000197165.6 | 3.041E-6 | 0.01 | 20035 | gtex_brain_ba24 |
| rs12448429 | 16 | 28588443 | SULT1A2 | ENSG00000197165.6 | 3.259E-6 | 0.01 | 19987 | gtex_brain_ba24 |
| rs4787455 | 16 | 28589455 | SULT1A2 | ENSG00000197165.6 | 3.042E-6 | 0.01 | 18975 | gtex_brain_ba24 |
| rs7190771 | 16 | 28590030 | SULT1A2 | ENSG00000197165.6 | 2.142E-6 | 0.01 | 18400 | gtex_brain_ba24 |
| rs112047757 | 16 | 28590862 | SULT1A2 | ENSG00000197165.6 | 3.042E-6 | 0.01 | 17568 | gtex_brain_ba24 |
| rs4788074 | 16 | 28593597 | SULT1A2 | ENSG00000197165.6 | 3.045E-6 | 0.01 | 14833 | gtex_brain_ba24 |
| rs4788073 | 16 | 28594549 | SULT1A2 | ENSG00000197165.6 | 3.045E-6 | 0.01 | 13881 | gtex_brain_ba24 |
| rs17640009 | 16 | 28595700 | SULT1A2 | ENSG00000197165.6 | 3.052E-6 | 0.01 | 12730 | gtex_brain_ba24 |
| rs75539558 | 16 | 28595810 | SULT1A2 | ENSG00000197165.6 | 3.052E-6 | 0.01 | 12620 | gtex_brain_ba24 |
| rs55792032 | 16 | 28599411 | SULT1A2 | ENSG00000197165.6 | 3.072E-6 | 0.01 | 9019 | gtex_brain_ba24 |
| rs62034359 | 16 | 28600091 | SULT1A2 | ENSG00000197165.6 | 3.014E-6 | 0.01 | 8339 | gtex_brain_ba24 |
| rs112479807 | 16 | 28600201 | SULT1A2 | ENSG00000197165.6 | 3.076E-6 | 0.01 | 8229 | gtex_brain_ba24 |
| rs2077031 | 16 | 28603168 | SULT1A2 | ENSG00000197165.6 | 3.288E-6 | 0.01 | 5262 | gtex_brain_ba24 |
| rs1059491 | 16 | 28603655 | SULT1A2 | ENSG00000197165.6 | 3.302E-6 | 0.01 | 4775 | gtex_brain_ba24 |
| rs62031560 | 16 | 28605915 | SULT1A2 | ENSG00000197165.6 | 3.186E-6 | 0.01 | 2515 | gtex_brain_ba24 |
| rs113208333 | 16 | 28606160 | SULT1A2 | ENSG00000197165.6 | 2.985E-6 | 0.01 | 2270 | gtex_brain_ba24 |
| rs4149406 | 16 | 28607070 | SULT1A2 | ENSG00000197165.6 | 2.876E-6 | 0.01 | 1360 | gtex_brain_ba24 |
| rs1690407 | 16 | 28607228 | SULT1A2 | ENSG00000197165.6 | 4.151E-6 | 0.01 | 1202 | gtex_brain_ba24 |
| rs743590 | 16 | 28608230 | SULT1A2 | ENSG00000197165.6 | 2.623E-6 | 0.01 | 200 | gtex_brain_ba24 |
| rs762633 | 16 | 28608341 | SULT1A2 | ENSG00000197165.6 | 2.631E-6 | 0.01 | 89 | gtex_brain_ba24 |
| rs35175818 | 16 | 28608746 | SULT1A2 | ENSG00000197165.6 | 2.542E-6 | 0.01 | -316 | gtex_brain_ba24 |
| rs11074907 | 16 | 28613965 | SULT1A2 | ENSG00000197165.6 | 9.099E-7 | 0.01 | -5535 | gtex_brain_ba24 |
| rs200784949 | 16 | 28616040 | SULT1A2 | ENSG00000197165.6 | 4.409E-6 | 0.01 | -7610 | gtex_brain_ba24 |
| rs6839 | 16 | 28617128 | SULT1A2 | ENSG00000197165.6 | 9.901E-7 | 0.01 | -8698 | gtex_brain_ba24 |
| rs41278162 | 16 | 28617361 | SULT1A2 | ENSG00000197165.6 | 3.785E-6 | 0.01 | -8931 | gtex_brain_ba24 |
| rs9282861 | 16 | 28617514 | SULT1A2 | ENSG00000197165.6 | 4.261E-6 | 0.01 | -9084 | gtex_brain_ba24 |
| rs2925624 | 16 | 28618545 | SULT1A2 | ENSG00000197165.6 | 3.292E-6 | 0.01 | -10115 | gtex_brain_ba24 |
| rs1690405 | 16 | 28620311 | SULT1A2 | ENSG00000197165.6 | 3.165E-6 | 0.01 | -11881 | gtex_brain_ba24 |
| rs149299 | 16 | 28485141 | SULT1A2 | ENSG00000197165.6 | 6.346E-7 | 0 | 123289 | gtex_brain_putamen_basal |
| rs151179 | 16 | 28487056 | SULT1A2 | ENSG00000197165.6 | 2.946E-7 | 0 | 121374 | gtex_brain_putamen_basal |
| rs201668183 | 16 | 28487212 | SULT1A2 | ENSG00000197165.6 | 2.058E-6 | 0 | 121218 | gtex_brain_putamen_basal |
| rs181195 | 16 | 28488369 | SULT1A2 | ENSG00000197165.6 | 6.319E-7 | 0 | 120061 | gtex_brain_putamen_basal |
| rs34839 | 16 | 28489346 | SULT1A2 | ENSG00000197165.6 | 2.688E-6 | 0 | 119084 | gtex_brain_putamen_basal |
| rs151181 | 16 | 28490517 | SULT1A2 | ENSG00000197165.6 | 2.946E-7 | 0 | 117913 | gtex_brain_putamen_basal |
| rs139457431 | 16 | 28491534 | SULT1A2 | ENSG00000197165.6 | 3.925E-7 | 0 | 116896 | gtex_brain_putamen_basal |
| rs151303 | 16 | 28492510 | SULT1A2 | ENSG00000197165.6 | 2.946E-7 | 0 | 115920 | gtex_brain_putamen_basal |
| rs34838 | 16 | 28494350 | SULT1A2 | ENSG00000197165.6 | 2.331E-6 | 0 | 114080 | gtex_brain_putamen_basal |
| rs42861 | 16 | 28494421 | SULT1A2 | ENSG00000197165.6 | 2.376E-6 | 0 | 114009 | gtex_brain_putamen_basal |
| rs34836 | 16 | 28494823 | SULT1A2 | ENSG00000197165.6 | 2.32E-6 | 0 | 113607 | gtex_brain_putamen_basal |
| rs151182 | 16 | 28495752 | SULT1A2 | ENSG00000197165.6 | 2.946E-7 | 0 | 112678 | gtex_brain_putamen_basal |
| rs151301 | 16 | 28497059 | SULT1A2 | ENSG00000197165.6 | 2.946E-7 | 0 | 111371 | gtex_brain_putamen_basal |
| rs34835 | 16 | 28499291 | SULT1A2 | ENSG00000197165.6 | 6.93E-7 | 0 | 109139 | gtex_brain_putamen_basal |
| rs149301 | 16 | 28499659 | SULT1A2 | ENSG00000197165.6 | 6.369E-7 | 0 | 108771 | gtex_brain_putamen_basal |
| rs200860698 | 16 | 28502409 | SULT1A2 | ENSG00000197165.6 | 1.08E-6 | 0 | 106021 | gtex_brain_putamen_basal |
| rs27741 | 16 | 28504181 | SULT1A2 | ENSG00000197165.6 | 2.994E-6 | 0 | 104249 | gtex_brain_putamen_basal |
| rs151174 | 16 | 28508069 | SULT1A2 | ENSG00000197165.6 | 3.02E-6 | 0 | 100361 | gtex_brain_putamen_basal |
| rs202174388 | 16 | 28512888 | SULT1A2 | ENSG00000197165.6 | 3.001E-6 | 0 | 95542 | gtex_brain_putamen_basal |
| rs153106 | 16 | 28526897 | SULT1A2 | ENSG00000197165.6 | 4.358E-7 | 0 | 81533 | gtex_brain_putamen_basal |
| rs240705 | 16 | 28529716 | SULT1A2 | ENSG00000197165.6 | 4.972E-7 | 0 | 78714 | gtex_brain_putamen_basal |
| rs240704 | 16 | 28529949 | SULT1A2 | ENSG00000197165.6 | 4.916E-7 | 0 | 78481 | gtex_brain_putamen_basal |
| rs4787458 | 16 | 28531287 | SULT1A2 | ENSG00000197165.6 | 1.127E-8 | 0 | 77143 | gtex_brain_putamen_basal |
| rs240702 | 16 | 28531353 | SULT1A2 | ENSG00000197165.6 | 4.582E-7 | 0 | 77077 | gtex_brain_putamen_basal |
| rs62034319 | 16 | 28532188 | SULT1A2 | ENSG00000197165.6 | 4.6E-7 | 0 | 76242 | gtex_brain_putamen_basal |
| rs28698667 | 16 | 28533071 | SULT1A2 | ENSG00000197165.6 | 1.829E-7 | 0 | 75359 | gtex_brain_putamen_basal |
| rs62034321 | 16 | 28534038 | SULT1A2 | ENSG00000197165.6 | 1.829E-7 | 0 | 74392 | gtex_brain_putamen_basal |
| rs4788085 | 16 | 28535003 | SULT1A2 | ENSG00000197165.6 | 1.866E-6 | 0 | 73427 | gtex_brain_putamen_basal |
| rs28772958 | 16 | 28535305 | SULT1A2 | ENSG00000197165.6 | 1.866E-6 | 0 | 73125 | gtex_brain_putamen_basal |
| rs62034322 | 16 | 28535834 | SULT1A2 | ENSG00000197165.6 | 6.59E-8 | 0 | 72596 | gtex_brain_putamen_basal |
| rs62034323 | 16 | 28536473 | SULT1A2 | ENSG00000197165.6 | 1.829E-7 | 0 | 71957 | gtex_brain_putamen_basal |
| rs62034324 | 16 | 28536762 | SULT1A2 | ENSG00000197165.6 | 1.724E-7 | 0 | 71668 | gtex_brain_putamen_basal |
| rs2106480 | 16 | 28537971 | SULT1A2 | ENSG00000197165.6 | 1.866E-6 | 0 | 70459 | gtex_brain_putamen_basal |
| rs62034325 | 16 | 28538640 | SULT1A2 | ENSG00000197165.6 | 7.271E-8 | 0 | 69790 | gtex_brain_putamen_basal |
| rs62034326 | 16 | 28539293 | SULT1A2 | ENSG00000197165.6 | 1.828E-7 | 0 | 69137 | gtex_brain_putamen_basal |
| rs189278832 | 16 | 28539386 | SULT1A2 | ENSG00000197165.6 | 7.908E-8 | 0 | 69044 | gtex_brain_putamen_basal |
| rs143626010 | 16 | 28539398 | SULT1A2 | ENSG00000197165.6 | 3.051E-6 | 0 | 69032 | gtex_brain_putamen_basal |
| rs4788084 | 16 | 28539848 | SULT1A2 | ENSG00000197165.6 | 1.901E-7 | 0 | 68582 | gtex_brain_putamen_basal |
| rs8046271 | 16 | 28541394 | SULT1A2 | ENSG00000197165.6 | 1.548E-7 | 0 | 67036 | gtex_brain_putamen_basal |
| rs12446550 | 16 | 28543381 | SULT1A2 | ENSG00000197165.6 | 1.829E-7 | 0 | 65049 | gtex_brain_putamen_basal |
| rs4788083 | 16 | 28545449 | SULT1A2 | ENSG00000197165.6 | 1.866E-6 | 0 | 62981 | gtex_brain_putamen_basal |
| rs3785354 | 16 | 28550667 | SULT1A2 | ENSG00000197165.6 | 8.409E-9 | 0 | 57763 | gtex_brain_putamen_basal |
| rs1074631 | 16 | 28554108 | SULT1A2 | ENSG00000197165.6 | 5.794E-9 | 0 | 54322 | gtex_brain_putamen_basal |
| rs4787457 | 16 | 28555400 | SULT1A2 | ENSG00000197165.6 | 8.636E-9 | 0 | 53030 | gtex_brain_putamen_basal |
| rs9926245 | 16 | 28555706 | SULT1A2 | ENSG00000197165.6 | 4.408E-7 | 0 | 52724 | gtex_brain_putamen_basal |
| rs4788081 | 16 | 28556147 | SULT1A2 | ENSG00000197165.6 | 5.794E-9 | 0 | 52283 | gtex_brain_putamen_basal |
| rs201107789 | 16 | 28556564 | SULT1A2 | ENSG00000197165.6 | 1.463E-8 | 0 | 51866 | gtex_brain_putamen_basal |
| rs4788080 | 16 | 28558081 | SULT1A2 | ENSG00000197165.6 | 9.075E-9 | 0 | 50349 | gtex_brain_putamen_basal |
| rs7202948 | 16 | 28558289 | SULT1A2 | ENSG00000197165.6 | 8.24E-7 | 0 | 50141 | gtex_brain_putamen_basal |
| rs4788079 | 16 | 28559363 | SULT1A2 | ENSG00000197165.6 | 6.013E-9 | 0 | 49067 | gtex_brain_putamen_basal |
| rs4787456 | 16 | 28559573 | SULT1A2 | ENSG00000197165.6 | 8.636E-9 | 0 | 48857 | gtex_brain_putamen_basal |
| rs4788078 | 16 | 28559981 | SULT1A2 | ENSG00000197165.6 | 8.636E-9 | 0 | 48449 | gtex_brain_putamen_basal |
| rs112366001 | 16 | 28561785 | SULT1A2 | ENSG00000197165.6 | 2.522E-7 | 0 | 46645 | gtex_brain_putamen_basal |
| rs13331170 | 16 | 28561982 | SULT1A2 | ENSG00000197165.6 | 9.227E-7 | 0 | 46448 | gtex_brain_putamen_basal |
| rs62034350 | 16 | 28562256 | SULT1A2 | ENSG00000197165.6 | 8.412E-9 | 0 | 46174 | gtex_brain_putamen_basal |
| rs62034351 | 16 | 28565489 | SULT1A2 | ENSG00000197165.6 | 9.627E-9 | 0 | 42941 | gtex_brain_putamen_basal |
| rs7191618 | 16 | 28565667 | SULT1A2 | ENSG00000197165.6 | 9.081E-7 | 0 | 42763 | gtex_brain_putamen_basal |
| rs7187604 | 16 | 28565953 | SULT1A2 | ENSG00000197165.6 | 5.863E-9 | 0 | 42477 | gtex_brain_putamen_basal |
| rs3859172 | 16 | 28566158 | SULT1A2 | ENSG00000197165.6 | 9.081E-7 | 0 | 42272 | gtex_brain_putamen_basal |
| rs4788077 | 16 | 28569764 | SULT1A2 | ENSG00000197165.6 | 1.531E-8 | 0 | 38666 | gtex_brain_putamen_basal |
| rs4788076 | 16 | 28570005 | SULT1A2 | ENSG00000197165.6 | 7.911E-9 | 0 | 38425 | gtex_brain_putamen_basal |
| rs370527719 | 16 | 28570703 | SULT1A2 | ENSG00000197165.6 | 1.553E-8 | 0 | 37727 | gtex_brain_putamen_basal |
| rs56272201 | 16 | 28580685 | SULT1A2 | ENSG00000197165.6 | 1.517E-8 | 0 | 27745 | gtex_brain_putamen_basal |
| rs56396270 | 16 | 28580829 | SULT1A2 | ENSG00000197165.6 | 8.566E-9 | 0 | 27601 | gtex_brain_putamen_basal |
| rs62034355 | 16 | 28581038 | SULT1A2 | ENSG00000197165.6 | 1.517E-8 | 0 | 27392 | gtex_brain_putamen_basal |
| rs12447461 | 16 | 28582941 | SULT1A2 | ENSG00000197165.6 | 8.555E-9 | 0 | 25489 | gtex_brain_putamen_basal |
| rs112191041 | 16 | 28583362 | SULT1A2 | ENSG00000197165.6 | 8.162E-9 | 0 | 25068 | gtex_brain_putamen_basal |
| rs111693583 | 16 | 28583610 | SULT1A2 | ENSG00000197165.6 | 8.57E-9 | 0 | 24820 | gtex_brain_putamen_basal |
| rs11074911 | 16 | 28583865 | SULT1A2 | ENSG00000197165.6 | 8.57E-9 | 0 | 24565 | gtex_brain_putamen_basal |
| rs56209193 | 16 | 28585636 | SULT1A2 | ENSG00000197165.6 | 8.042E-9 | 0 | 22794 | gtex_brain_putamen_basal |
| rs7193402 | 16 | 28586127 | SULT1A2 | ENSG00000197165.6 | 8.584E-9 | 0 | 22303 | gtex_brain_putamen_basal |
| rs7186573 | 16 | 28587389 | SULT1A2 | ENSG00000197165.6 | 8.803E-9 | 0 | 21041 | gtex_brain_putamen_basal |
| rs62034358 | 16 | 28587597 | SULT1A2 | ENSG00000197165.6 | 8.588E-9 | 0 | 20833 | gtex_brain_putamen_basal |
| rs12445823 | 16 | 28588049 | SULT1A2 | ENSG00000197165.6 | 8.603E-9 | 0 | 20381 | gtex_brain_putamen_basal |
| rs12445744 | 16 | 28588395 | SULT1A2 | ENSG00000197165.6 | 8.603E-9 | 0 | 20035 | gtex_brain_putamen_basal |
| rs12448429 | 16 | 28588443 | SULT1A2 | ENSG00000197165.6 | 8.644E-9 | 0 | 19987 | gtex_brain_putamen_basal |
| rs4787455 | 16 | 28589455 | SULT1A2 | ENSG00000197165.6 | 8.607E-9 | 0 | 18975 | gtex_brain_putamen_basal |
| rs7190771 | 16 | 28590030 | SULT1A2 | ENSG00000197165.6 | 6.678E-9 | 0 | 18400 | gtex_brain_putamen_basal |
| rs112047757 | 16 | 28590862 | SULT1A2 | ENSG00000197165.6 | 8.607E-9 | 0 | 17568 | gtex_brain_putamen_basal |
| rs112831778 | 16 | 28590989 | SULT1A2 | ENSG00000197165.6 | 1.528E-8 | 0 | 17441 | gtex_brain_putamen_basal |
| rs17707300 | 16 | 28593347 | SULT1A2 | ENSG00000197165.6 | 8.636E-9 | 0 | 15083 | gtex_brain_putamen_basal |
| rs4788074 | 16 | 28593597 | SULT1A2 | ENSG00000197165.6 | 8.636E-9 | 0 | 14833 | gtex_brain_putamen_basal |
| rs4788073 | 16 | 28594549 | SULT1A2 | ENSG00000197165.6 | 8.636E-9 | 0 | 13881 | gtex_brain_putamen_basal |
| rs17640009 | 16 | 28595700 | SULT1A2 | ENSG00000197165.6 | 8.151E-9 | 0 | 12730 | gtex_brain_putamen_basal |
| rs75539558 | 16 | 28595810 | SULT1A2 | ENSG00000197165.6 | 7.995E-9 | 0 | 12620 | gtex_brain_putamen_basal |
| rs55792032 | 16 | 28599411 | SULT1A2 | ENSG00000197165.6 | 8.207E-9 | 0 | 9019 | gtex_brain_putamen_basal |
| rs62034359 | 16 | 28600091 | SULT1A2 | ENSG00000197165.6 | 8.29E-9 | 0 | 8339 | gtex_brain_putamen_basal |
| rs112479807 | 16 | 28600201 | SULT1A2 | ENSG00000197165.6 | 8.137E-9 | 0 | 8229 | gtex_brain_putamen_basal |
| rs2077031 | 16 | 28603168 | SULT1A2 | ENSG00000197165.6 | 6.83E-9 | 0 | 5262 | gtex_brain_putamen_basal |
| rs762634 | 16 | 28603335 | SULT1A2 | ENSG00000197165.6 | 5.58E-9 | 0 | 5095 | gtex_brain_putamen_basal |
| rs710410 | 16 | 28603342 | SULT1A2 | ENSG00000197165.6 | 6.577E-9 | 0 | 5088 | gtex_brain_putamen_basal |
| rs1059491 | 16 | 28603655 | SULT1A2 | ENSG00000197165.6 | 6.777E-9 | 0 | 4775 | gtex_brain_putamen_basal |
| rs62031560 | 16 | 28605915 | SULT1A2 | ENSG00000197165.6 | 5.867E-9 | 0 | 2515 | gtex_brain_putamen_basal |
| rs113208333 | 16 | 28606160 | SULT1A2 | ENSG00000197165.6 | 6.191E-9 | 0 | 2270 | gtex_brain_putamen_basal |
| rs4149406 | 16 | 28607070 | SULT1A2 | ENSG00000197165.6 | 5.744E-9 | 0 | 1360 | gtex_brain_putamen_basal |
| rs1690407 | 16 | 28607228 | SULT1A2 | ENSG00000197165.6 | 2.316E-6 | 0 | 1202 | gtex_brain_putamen_basal |
| rs1136703 | 16 | 28607232 | SULT1A2 | ENSG00000197165.6 | 3.267E-6 | 0 | 1198 | gtex_brain_putamen_basal |
| rs4115668 | 16 | 28607532 | SULT1A2 | ENSG00000197165.6 | 7.474E-9 | 0 | 898 | gtex_brain_putamen_basal |
| rs743590 | 16 | 28608230 | SULT1A2 | ENSG00000197165.6 | 5.407E-9 | 0 | 200 | gtex_brain_putamen_basal |
| rs762633 | 16 | 28608341 | SULT1A2 | ENSG00000197165.6 | 5.415E-9 | 0 | 89 | gtex_brain_putamen_basal |
| rs35175818 | 16 | 28608746 | SULT1A2 | ENSG00000197165.6 | 5.374E-9 | 0 | -316 | gtex_brain_putamen_basal |
| rs4149398 | 16 | 28608938 | SULT1A2 | ENSG00000197165.6 | 1.779E-8 | 0 | -508 | gtex_brain_putamen_basal |
| rs62031562 | 16 | 28609329 | SULT1A2 | ENSG00000197165.6 | 1.583E-8 | 0 | -899 | gtex_brain_putamen_basal |
| rs11074907 | 16 | 28613965 | SULT1A2 | ENSG00000197165.6 | 3.637E-9 | 0 | -5535 | gtex_brain_putamen_basal |
| rs7192601 | 16 | 28614488 | SULT1A2 | ENSG00000197165.6 | 1.376E-8 | 0 | -6058 | gtex_brain_putamen_basal |
| rs7191548 | 16 | 28614734 | SULT1A2 | ENSG00000197165.6 | 1.333E-8 | 0 | -6304 | gtex_brain_putamen_basal |
| rs200784949 | 16 | 28616040 | SULT1A2 | ENSG00000197165.6 | 3.35E-6 | 0 | -7610 | gtex_brain_putamen_basal |
| rs6498091 | 16 | 28616259 | SULT1A2 | ENSG00000197165.6 | 1.542E-8 | 0 | -7829 | gtex_brain_putamen_basal |
| rs4788070 | 16 | 28616399 | SULT1A2 | ENSG00000197165.6 | 1.752E-8 | 0 | -7969 | gtex_brain_putamen_basal |
| rs4788069 | 16 | 28616665 | SULT1A2 | ENSG00000197165.6 | 1.647E-8 | 0 | -8235 | gtex_brain_putamen_basal |
| rs4788068 | 16 | 28616723 | SULT1A2 | ENSG00000197165.6 | 1.655E-8 | 0 | -8293 | gtex_brain_putamen_basal |
| rs1042157 | 16 | 28617057 | SULT1A2 | ENSG00000197165.6 | 1.732E-8 | 0 | -8627 | gtex_brain_putamen_basal |
| rs6839 | 16 | 28617128 | SULT1A2 | ENSG00000197165.6 | 1.164E-8 | 0 | -8698 | gtex_brain_putamen_basal |
| rs9282864 | 16 | 28617308 | SULT1A2 | ENSG00000197165.6 | 1.486E-6 | 0 | -8878 | gtex_brain_putamen_basal |
| rs41278162 | 16 | 28617361 | SULT1A2 | ENSG00000197165.6 | 8.246E-9 | 0 | -8931 | gtex_brain_putamen_basal |
| rs9282861 | 16 | 28617514 | SULT1A2 | ENSG00000197165.6 | 7.767E-9 | 0 | -9084 | gtex_brain_putamen_basal |
| rs3176926 | 16 | 28617552 | SULT1A2 | ENSG00000197165.6 | 4.283E-7 | 0 | -9122 | gtex_brain_putamen_basal |
| rs4149394 | 16 | 28617574 | SULT1A2 | ENSG00000197165.6 | 1.014E-6 | 0 | -9144 | gtex_brain_putamen_basal |
| rs4149393 | 16 | 28617595 | SULT1A2 | ENSG00000197165.6 | 1.863E-7 | 0 | -9165 | gtex_brain_putamen_basal |
| rs79533802 | 16 | 28617794 | SULT1A2 | ENSG00000197165.6 | 1.377E-6 | 0 | -9364 | gtex_brain_putamen_basal |
| rs79039694 | 16 | 28617795 | SULT1A2 | ENSG00000197165.6 | 1.405E-6 | 0 | -9365 | gtex_brain_putamen_basal |
| rs4149392 | 16 | 28617813 | SULT1A2 | ENSG00000197165.6 | 4.196E-8 | 0 | -9383 | gtex_brain_putamen_basal |
| rs200409943 | 16 | 28617884 | SULT1A2 | ENSG00000197165.6 | 1.185E-6 | 0 | -9454 | gtex_brain_putamen_basal |
| rs75301646 | 16 | 28617885 | SULT1A2 | ENSG00000197165.6 | 2.871E-8 | 0 | -9455 | gtex_brain_putamen_basal |
| rs74459546 | 16 | 28617888 | SULT1A2 | ENSG00000197165.6 | 3.351E-8 | 0 | -9458 | gtex_brain_putamen_basal |
| rs116840534 | 16 | 28617890 | SULT1A2 | ENSG00000197165.6 | 2.789E-8 | 0 | -9460 | gtex_brain_putamen_basal |
| rs143299878 | 16 | 28617930 | SULT1A2 | ENSG00000197165.6 | 9.253E-9 | 0 | -9500 | gtex_brain_putamen_basal |
| rs111384198 | 16 | 28617934 | SULT1A2 | ENSG00000197165.6 | 1.348E-8 | 0 | -9504 | gtex_brain_putamen_basal |
| rs4149391 | 16 | 28617971 | SULT1A2 | ENSG00000197165.6 | 1.703E-8 | 0 | -9541 | gtex_brain_putamen_basal |
| rs4149390 | 16 | 28617974 | SULT1A2 | ENSG00000197165.6 | 1.702E-8 | 0 | -9544 | gtex_brain_putamen_basal |
| rs41278158 | 16 | 28617993 | SULT1A2 | ENSG00000197165.6 | 1.516E-8 | 0 | -9563 | gtex_brain_putamen_basal |
| rs4149389 | 16 | 28618011 | SULT1A2 | ENSG00000197165.6 | 2.886E-7 | 0 | -9581 | gtex_brain_putamen_basal |
| rs34954534 | 16 | 28618018 | SULT1A2 | ENSG00000197165.6 | 1.084E-8 | 0 | -9588 | gtex_brain_putamen_basal |
| rs41278156 | 16 | 28618037 | SULT1A2 | ENSG00000197165.6 | 4.028E-7 | 0 | -9607 | gtex_brain_putamen_basal |
| rs4149388 | 16 | 28618047 | SULT1A2 | ENSG00000197165.6 | 1.789E-7 | 0 | -9617 | gtex_brain_putamen_basal |
| rs3020806 | 16 | 28618065 | SULT1A2 | ENSG00000197165.6 | 1.244E-7 | 0 | -9635 | gtex_brain_putamen_basal |
| rs74752114 | 16 | 28618068 | SULT1A2 | ENSG00000197165.6 | 1.239E-7 | 0 | -9638 | gtex_brain_putamen_basal |
| rs3020805 | 16 | 28618071 | SULT1A2 | ENSG00000197165.6 | 1.243E-7 | 0 | -9641 | gtex_brain_putamen_basal |
| rs9282862 | 16 | 28618237 | SULT1A2 | ENSG00000197165.6 | 6.102E-7 | 0 | -9807 | gtex_brain_putamen_basal |
| rs2925623 | 16 | 28618446 | SULT1A2 | ENSG00000197165.6 | 1.861E-8 | 0 | -10016 | gtex_brain_putamen_basal |
| rs2925624 | 16 | 28618545 | SULT1A2 | ENSG00000197165.6 | 4.112E-9 | 0 | -10115 | gtex_brain_putamen_basal |
| rs3020804 | 16 | 28618636 | SULT1A2 | ENSG00000197165.6 | 1.452E-8 | 0 | -10206 | gtex_brain_putamen_basal |
| rs3020803 | 16 | 28618914 | SULT1A2 | ENSG00000197165.6 | 4.752E-8 | 0 | -10484 | gtex_brain_putamen_basal |
| rs2925629 | 16 | 28619076 | SULT1A2 | ENSG00000197165.6 | 1.957E-8 | 0 | -10646 | gtex_brain_putamen_basal |
| rs2925630 | 16 | 28619132 | SULT1A2 | ENSG00000197165.6 | 1.922E-8 | 0 | -10702 | gtex_brain_putamen_basal |
| rs56169261 | 16 | 28619178 | SULT1A2 | ENSG00000197165.6 | 3.044E-7 | 0 | -10748 | gtex_brain_putamen_basal |
| rs56091264 | 16 | 28619179 | SULT1A2 | ENSG00000197165.6 | 8.412E-7 | 0 | -10749 | gtex_brain_putamen_basal |
| rs56305122 | 16 | 28619180 | SULT1A2 | ENSG00000197165.6 | 1.117E-6 | 0 | -10750 | gtex_brain_putamen_basal |
| rs1126447 | 16 | 28619911 | SULT1A2 | ENSG00000197165.6 | 1.351E-7 | 0 | -11481 | gtex_brain_putamen_basal |
| rs1690405 | 16 | 28620311 | SULT1A2 | ENSG00000197165.6 | 3.651E-8 | 0 | -11881 | gtex_brain_putamen_basal |
| rs4787452 | 16 | 28623115 | SULT1A2 | ENSG00000197165.6 | 4.438E-7 | 0 | -14685 | gtex_brain_putamen_basal |
| rs28729187 | 16 | 28626966 | SULT1A2 | ENSG00000197165.6 | 3.243E-6 | 0 | -18536 | gtex_brain_putamen_basal |
| rs28480369 | 16 | 28627004 | SULT1A2 | ENSG00000197165.6 | 3.262E-6 | 0 | -18574 | gtex_brain_putamen_basal |
| rs28676837 | 16 | 28627063 | SULT1A2 | ENSG00000197165.6 | 3.388E-6 | 0 | -18633 | gtex_brain_putamen_basal |
| rs398119327 | 16 | 28628326 | SULT1A2 | ENSG00000197165.6 | 2.953E-6 | 0 | -19896 | gtex_brain_putamen_basal |
| rs62031607 | 16 | 28631530 | SULT1A2 | ENSG00000197165.6 | 3.172E-7 | 0 | -23100 | gtex_brain_putamen_basal |
| rs2411453 | 16 | 28632021 | SULT1A2 | ENSG00000197165.6 | 2.303E-6 | 0 | -23591 | gtex_brain_putamen_basal |
| rs4788062 | 16 | 28641179 | SULT1A2 | ENSG00000197165.6 | 1.364E-7 | 0 | -32749 | gtex_brain_putamen_basal |
| rs35626515 | 16 | 28649651 | SULT1A2 | ENSG00000197165.6 | 1.964E-7 | 0 | -41221 | gtex_brain_putamen_basal |
| rs62036613 | 16 | 28823097 | SULT1A2 | ENSG00000197165.6 | 2.083E-6 | 0 | -214667 | gtex_brain_putamen_basal |
| rs62036614 | 16 | 28824685 | SULT1A2 | ENSG00000197165.6 | 2.148E-6 | 0 | -216255 | gtex_brain_putamen_basal |
| rs62036618 | 16 | 28828834 | SULT1A2 | ENSG00000197165.6 | 1.197E-6 | 0 | -220404 | gtex_brain_putamen_basal |
| rs80275162 | 16 | 28863517 | SULT1A2 | ENSG00000197165.6 | 2.912E-6 | 0 | -255087 | gtex_brain_putamen_basal |
| rs149601295 | 16 | 28867159 | SULT1A2 | ENSG00000197165.6 | 2.196E-6 | 0 | -258729 | gtex_brain_putamen_basal |
| rs534187694 | 16 | 28910965 | SULT1A2 | ENSG00000197165.6 | 2.287E-6 | 0 | -302535 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FEN1 | 0.83 | 0.79 |
| RNF26 | 0.82 | 0.80 |
| USP11 | 0.80 | 0.79 |
| COG8 | 0.80 | 0.76 |
| PANK4 | 0.79 | 0.76 |
| FAM53C | 0.79 | 0.78 |
| MAEA | 0.79 | 0.77 |
| SPG7 | 0.79 | 0.75 |
| FOXRED2 | 0.78 | 0.79 |
| MUL1 | 0.78 | 0.78 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.67 | -0.61 |
| MT-CO2 | -0.65 | -0.56 |
| AF347015.31 | -0.64 | -0.56 |
| MT-CYB | -0.62 | -0.54 |
| AF347015.8 | -0.62 | -0.56 |
| NOSTRIN | -0.61 | -0.53 |
| HIGD1B | -0.61 | -0.52 |
| AF347015.33 | -0.61 | -0.52 |
| AF347015.2 | -0.60 | -0.48 |
| AC098691.2 | -0.58 | -0.58 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0004062 | aryl sulfotransferase activity | IEA | dopamine (GO term level: 6) | - |
| GO:0016740 | transferase activity | IEA | - | |
| GO:0008146 | sulfotransferase activity | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0008202 | steroid metabolic process | IEA | - | |
| GO:0009309 | amine biosynthetic process | TAS | 9119390 | |
| GO:0006629 | lipid metabolic process | IEA | - | |
| GO:0006584 | catecholamine metabolic process | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005737 | cytoplasm | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG SULFUR METABOLISM | 13 | 8 | All SZGR 2.0 genes in this pathway |
| REACTOME BIOLOGICAL OXIDATIONS | 139 | 91 | All SZGR 2.0 genes in this pathway |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 14 | 10 | All SZGR 2.0 genes in this pathway |
| REACTOME PHASE II CONJUGATION | 70 | 42 | All SZGR 2.0 genes in this pathway |
| PARENT MTOR SIGNALING UP | 567 | 375 | All SZGR 2.0 genes in this pathway |
| RODRIGUES NTN1 TARGETS DN | 158 | 102 | All SZGR 2.0 genes in this pathway |
| HAHTOLA MYCOSIS FUNGOIDES CD4 UP | 64 | 46 | All SZGR 2.0 genes in this pathway |
| DEBIASI APOPTOSIS BY REOVIRUS INFECTION DN | 287 | 208 | All SZGR 2.0 genes in this pathway |