Gene Page: SULT1C2

Summary ?
GeneID6819
SymbolSULT1C2
SynonymsST1C1|ST1C2|SULT1C1|humSULTC2
Descriptionsulfotransferase family 1C member 2
ReferenceMIM:602385|HGNC:HGNC:11456|Ensembl:ENSG00000198203|HPRD:03858|Vega:OTTHUMG00000153215
Gene typeprotein-coding
Map location2q12.3
Pascal p-value0.02
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IGenome scan meta-analysisPsr: 0.0004 
GSMA_IIAGenome scan meta-analysis (All samples)Psr: 0.00755 

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10994209chr1061877705SULT1C268190.14trans
rs126173322108886551SULT1C2ENSG00000198203.51.922E-80-18544gtex_brain_ba24
rs130034612108889658SULT1C2ENSG00000198203.51.697E-80-15437gtex_brain_ba24
rs67609182108904340SULT1C2ENSG00000198203.55.068E-130-755gtex_brain_ba24
rs23054842108905030SULT1C2ENSG00000198203.52.581E-60-65gtex_brain_ba24
rs23054852108905048SULT1C2ENSG00000198203.54.058E-110-47gtex_brain_ba24
rs101735542108907361SULT1C2ENSG00000198203.52.106E-702266gtex_brain_ba24
rs134245302108909401SULT1C2ENSG00000198203.52.106E-704306gtex_brain_ba24
rs170360612108911809SULT1C2ENSG00000198203.52.106E-706714gtex_brain_ba24
rs360553222108911904SULT1C2ENSG00000198203.52.106E-706809gtex_brain_ba24
rs134103052108912673SULT1C2ENSG00000198203.54.931E-807578gtex_brain_ba24
rs121045902108913012SULT1C2ENSG00000198203.52.897E-907917gtex_brain_ba24
rs41494202108913090SULT1C2ENSG00000198203.54.979E-807995gtex_brain_ba24
rs41494232108916044SULT1C2ENSG00000198203.52.877E-9010949gtex_brain_ba24
rs126200502108919798SULT1C2ENSG00000198203.51.375E-6014703gtex_brain_ba24
rs21984662108926967SULT1C2ENSG00000198203.51.658E-6021872gtex_brain_ba24
rs46761942108928082SULT1C2ENSG00000198203.54.451E-7022987gtex_brain_ba24
rs67232742108884790SULT1C2ENSG00000198203.59.318E-70-20305gtex_brain_putamen_basal
rs130241692108885125SULT1C2ENSG00000198203.55.089E-60-19970gtex_brain_putamen_basal
rs65427582108885748SULT1C2ENSG00000198203.54.432E-60-19347gtex_brain_putamen_basal
rs126173322108886551SULT1C2ENSG00000198203.54.696E-80-18544gtex_brain_putamen_basal
rs130034612108889658SULT1C2ENSG00000198203.58.498E-80-15437gtex_brain_putamen_basal
rs67609182108904340SULT1C2ENSG00000198203.54.95E-130-755gtex_brain_putamen_basal
rs23054842108905030SULT1C2ENSG00000198203.51.091E-70-65gtex_brain_putamen_basal
rs23054852108905048SULT1C2ENSG00000198203.54.017E-100-47gtex_brain_putamen_basal
rs101735542108907361SULT1C2ENSG00000198203.59.039E-702266gtex_brain_putamen_basal
rs134245302108909401SULT1C2ENSG00000198203.59.039E-704306gtex_brain_putamen_basal
rs170360612108911809SULT1C2ENSG00000198203.59.039E-706714gtex_brain_putamen_basal
rs360553222108911904SULT1C2ENSG00000198203.59.039E-706809gtex_brain_putamen_basal
rs134103052108912673SULT1C2ENSG00000198203.55.938E-1007578gtex_brain_putamen_basal
rs121045902108913012SULT1C2ENSG00000198203.55.981E-1007917gtex_brain_putamen_basal
rs41494202108913090SULT1C2ENSG00000198203.55.947E-1007995gtex_brain_putamen_basal
rs41494232108916044SULT1C2ENSG00000198203.55.934E-12010949gtex_brain_putamen_basal
rs126200502108919798SULT1C2ENSG00000198203.51.695E-10014703gtex_brain_putamen_basal
rs21984662108926967SULT1C2ENSG00000198203.52.94E-9021872gtex_brain_putamen_basal
rs46761942108928082SULT1C2ENSG00000198203.59.336E-11022987gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0016740transferase activityIEA-
GO:0008146sulfotransferase activityTAS9169148 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0009308cellular amine metabolic processTAS9169148 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005856cytoskeletonIDA18029348 
GO:0005737cytoplasmTAS9169148 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME BIOLOGICAL OXIDATIONS 13991All SZGR 2.0 genes in this pathway
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 1410All SZGR 2.0 genes in this pathway
REACTOME PHASE II CONJUGATION 7042All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS DN 384230All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER ADVANCED VS EARLY DN 13870All SZGR 2.0 genes in this pathway
BARRIER COLON CANCER RECURRENCE UP 4228All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D DN 14383All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584356All SZGR 2.0 genes in this pathway
AUNG GASTRIC CANCER 5420All SZGR 2.0 genes in this pathway
PATTERSON DOCETAXEL RESISTANCE 2920All SZGR 2.0 genes in this pathway
GRUETZMANN PANCREATIC CANCER UP 358245All SZGR 2.0 genes in this pathway
LIAO METASTASIS 539324All SZGR 2.0 genes in this pathway
CERVERA SDHB TARGETS 2 11476All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546351All SZGR 2.0 genes in this pathway
LENAOUR DENDRITIC CELL MATURATION UP 11484All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY NO BLOOD DN 15093All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY DN 14588All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER WITH H3K9ME3 UP 14175All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS DN 7043All SZGR 2.0 genes in this pathway
HAN SATB1 TARGETS UP 395249All SZGR 2.0 genes in this pathway
HAN SATB1 TARGETS DN 442275All SZGR 2.0 genes in this pathway
TAVAZOIE METASTASIS 10868All SZGR 2.0 genes in this pathway
YAMASHITA LIVER CANCER STEM CELL DN 7651All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 UP 430288All SZGR 2.0 genes in this pathway
SUMI HNF4A TARGETS 3414All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS DN 10971All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP 289184All SZGR 2.0 genes in this pathway