Gene Page: TAL2
Summary ?
| GeneID | 6887 |
| Symbol | TAL2 |
| Synonyms | - |
| Description | T-cell acute lymphocytic leukemia 2 |
| Reference | MIM:186855|HGNC:HGNC:11557|Ensembl:ENSG00000186051|HPRD:01735|Vega:OTTHUMG00000020424 |
| Gene type | protein-coding |
| Map location | 9q32 |
| Pascal p-value | 0.011 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TRMU | 0.50 | 0.51 |
| AC091196.1 | 0.50 | 0.51 |
| CDC37 | 0.49 | 0.49 |
| RNF215 | 0.48 | 0.52 |
| CSNK1G2 | 0.48 | 0.50 |
| CDK10 | 0.47 | 0.50 |
| BRSK1 | 0.47 | 0.48 |
| TAF6 | 0.47 | 0.49 |
| ZNF839 | 0.47 | 0.50 |
| AMDHD2 | 0.47 | 0.51 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.41 | -0.39 |
| AF347015.31 | -0.40 | -0.37 |
| MT-ATP8 | -0.40 | -0.37 |
| AF347015.8 | -0.40 | -0.34 |
| AF347015.27 | -0.39 | -0.36 |
| MT-CO2 | -0.38 | -0.34 |
| MT-CYB | -0.38 | -0.36 |
| AF347015.18 | -0.38 | -0.32 |
| NOSTRIN | -0.37 | -0.35 |
| GNG11 | -0.36 | -0.40 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KONG E2F3 TARGETS | 97 | 58 | All SZGR 2.0 genes in this pathway |
| RIZ ERYTHROID DIFFERENTIATION HBZ | 41 | 27 | All SZGR 2.0 genes in this pathway |
| RIZ ERYTHROID DIFFERENTIATION HEMGN | 31 | 21 | All SZGR 2.0 genes in this pathway |
| MYLLYKANGAS AMPLIFICATION HOT SPOT 8 | 18 | 7 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS NEUROEPITHELIUM DN | 164 | 111 | All SZGR 2.0 genes in this pathway |
| LENAOUR DENDRITIC CELL MATURATION DN | 128 | 90 | All SZGR 2.0 genes in this pathway |
| GRESHOCK CANCER COPY NUMBER UP | 323 | 240 | All SZGR 2.0 genes in this pathway |
| MEISSNER ES ICP WITH H3K4ME3 | 34 | 17 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MCV6 ICP WITH H3K4ME3 AND H3K27ME3 | 34 | 21 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF ICP WITH H3K4ME3 AND H3K27ME3 | 38 | 34 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| GOBERT CORE OLIGODENDROCYTE DIFFERENTIATION | 40 | 28 | All SZGR 2.0 genes in this pathway |