Gene Page: THRSP
Summary ?
GeneID | 7069 |
Symbol | THRSP |
Synonyms | LPGP1|Lpgp|S14|SPOT14|THRP |
Description | thyroid hormone responsive |
Reference | MIM:601926|HGNC:HGNC:11800|Ensembl:ENSG00000151365|HPRD:03566|Vega:OTTHUMG00000166632 |
Gene type | protein-coding |
Map location | 11q14.1 |
Pascal p-value | 0.018 |
eGene | Cerebellar Hemisphere Cerebellum Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RRM1 | 0.94 | 0.93 |
WDHD1 | 0.93 | 0.92 |
FAM60A | 0.93 | 0.76 |
PPM1D | 0.93 | 0.93 |
ACTL6A | 0.93 | 0.71 |
MSH6 | 0.92 | 0.92 |
LMNB1 | 0.91 | 0.86 |
SP3 | 0.91 | 0.95 |
C6orf167 | 0.91 | 0.87 |
PRPF40A | 0.91 | 0.92 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
C5orf53 | -0.56 | -0.74 |
PTH1R | -0.55 | -0.74 |
HLA-F | -0.55 | -0.74 |
AIFM3 | -0.54 | -0.73 |
AF347015.31 | -0.54 | -0.86 |
SLC16A11 | -0.53 | -0.64 |
SLC9A3R2 | -0.53 | -0.49 |
TNFSF12 | -0.53 | -0.61 |
AF347015.27 | -0.53 | -0.83 |
MT-CO2 | -0.53 | -0.88 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION DN | 234 | 147 | All SZGR 2.0 genes in this pathway |
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL DN | 114 | 58 | All SZGR 2.0 genes in this pathway |
KHETCHOUMIAN TRIM24 TARGETS DN | 8 | 7 | All SZGR 2.0 genes in this pathway |
NIKOLSKY BREAST CANCER 11Q12 Q14 AMPLICON | 158 | 93 | All SZGR 2.0 genes in this pathway |
LE EGR2 TARGETS DN | 108 | 84 | All SZGR 2.0 genes in this pathway |
YAO HOXA10 TARGETS VIA PROGESTERONE UP | 79 | 58 | All SZGR 2.0 genes in this pathway |
NADLER OBESITY DN | 48 | 34 | All SZGR 2.0 genes in this pathway |
RUAN RESPONSE TO TNF UP | 12 | 10 | All SZGR 2.0 genes in this pathway |
SCHLINGEMANN SKIN CARCINOGENESIS TPA DN | 29 | 15 | All SZGR 2.0 genes in this pathway |
BURTON ADIPOGENESIS 6 | 189 | 112 | All SZGR 2.0 genes in this pathway |
MARTINEZ RB1 TARGETS UP | 673 | 430 | All SZGR 2.0 genes in this pathway |
MARTINEZ TP53 TARGETS UP | 602 | 364 | All SZGR 2.0 genes in this pathway |
MARTINEZ RB1 AND TP53 TARGETS UP | 601 | 369 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER DN | 540 | 340 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN | 274 | 165 | All SZGR 2.0 genes in this pathway |
ZHENG GLIOBLASTOMA PLASTICITY UP | 250 | 168 | All SZGR 2.0 genes in this pathway |
CADWELL ATG16L1 TARGETS UP | 93 | 56 | All SZGR 2.0 genes in this pathway |
YOSHIOKA LIVER CANCER EARLY RECURRENCE DN | 65 | 31 | All SZGR 2.0 genes in this pathway |
MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 9 | 76 | 45 | All SZGR 2.0 genes in this pathway |
BAUS TFF2 TARGETS DN | 11 | 7 | All SZGR 2.0 genes in this pathway |
RUAN RESPONSE TO TROGLITAZONE DN | 19 | 14 | All SZGR 2.0 genes in this pathway |
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D | 882 | 506 | All SZGR 2.0 genes in this pathway |
DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |