Gene Page: TTC3
Summary ?
| GeneID | 7267 |
| Symbol | TTC3 |
| Synonyms | DCRR1|RNF105|TPRDIII |
| Description | tetratricopeptide repeat domain 3 |
| Reference | MIM:602259|HGNC:HGNC:12393|Ensembl:ENSG00000182670|HPRD:03773|Vega:OTTHUMG00000086654 |
| Gene type | protein-coding |
| Map location | 21q22.2 |
| Pascal p-value | 0.21 |
| Sherlock p-value | 0.006 |
| Fetal beta | 1.441 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Meta |
| Support | CompositeSet Darnell FMRP targets Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg24693520 | 21 | 38445266 | PIGP;TTC3 | 1.815E-4 | -0.365 | 0.034 | DMG:Wockner_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs1235345 | 21 | 38432325 | TTC3 | ENSG00000182670.9 | 1.158E-8 | 0 | -13201 | gtex_brain_putamen_basal |
| rs2249947 | 21 | 38433519 | TTC3 | ENSG00000182670.9 | 3.45E-9 | 0 | -12007 | gtex_brain_putamen_basal |
| rs397760628 | 21 | 38436954 | TTC3 | ENSG00000182670.9 | 3.221E-9 | 0 | -8572 | gtex_brain_putamen_basal |
| rs8127496 | 21 | 38442482 | TTC3 | ENSG00000182670.9 | 3.45E-9 | 0 | -3044 | gtex_brain_putamen_basal |
| rs28503645 | 21 | 38443674 | TTC3 | ENSG00000182670.9 | 5.652E-10 | 0 | -1852 | gtex_brain_putamen_basal |
| rs2298682 | 21 | 38444890 | TTC3 | ENSG00000182670.9 | 2.81E-9 | 0 | -636 | gtex_brain_putamen_basal |
| rs2298683 | 21 | 38445069 | TTC3 | ENSG00000182670.9 | 6.537E-9 | 0 | -457 | gtex_brain_putamen_basal |
| rs2298684 | 21 | 38445095 | TTC3 | ENSG00000182670.9 | 2.712E-9 | 0 | -431 | gtex_brain_putamen_basal |
| rs8128474 | 21 | 38446319 | TTC3 | ENSG00000182670.9 | 1.367E-6 | 0 | 793 | gtex_brain_putamen_basal |
| rs1543748 | 21 | 38446581 | TTC3 | ENSG00000182670.9 | 3.084E-9 | 0 | 1055 | gtex_brain_putamen_basal |
| rs1543749 | 21 | 38446621 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 1095 | gtex_brain_putamen_basal |
| rs1543750 | 21 | 38446918 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 1392 | gtex_brain_putamen_basal |
| rs5843790 | 21 | 38446955 | TTC3 | ENSG00000182670.9 | 2.956E-9 | 0 | 1429 | gtex_brain_putamen_basal |
| rs11412056 | 21 | 38446961 | TTC3 | ENSG00000182670.9 | 5.816E-8 | 0 | 1435 | gtex_brain_putamen_basal |
| rs4817843 | 21 | 38447040 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 1514 | gtex_brain_putamen_basal |
| rs4817844 | 21 | 38447064 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 1538 | gtex_brain_putamen_basal |
| rs4817845 | 21 | 38447132 | TTC3 | ENSG00000182670.9 | 3.025E-9 | 0 | 1606 | gtex_brain_putamen_basal |
| rs6517402 | 21 | 38447423 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 1897 | gtex_brain_putamen_basal |
| rs8133549 | 21 | 38447489 | TTC3 | ENSG00000182670.9 | 3.033E-9 | 0 | 1963 | gtex_brain_putamen_basal |
| rs1155785 | 21 | 38447939 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 2413 | gtex_brain_putamen_basal |
| rs1155786 | 21 | 38448025 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 2499 | gtex_brain_putamen_basal |
| rs1155787 | 21 | 38448069 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 2543 | gtex_brain_putamen_basal |
| rs60447195 | 21 | 38448600 | TTC3 | ENSG00000182670.9 | 2.096E-9 | 0 | 3074 | gtex_brain_putamen_basal |
| rs1015549 | 21 | 38448880 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 3354 | gtex_brain_putamen_basal |
| rs1015551 | 21 | 38449510 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 3984 | gtex_brain_putamen_basal |
| rs7280371 | 21 | 38450008 | TTC3 | ENSG00000182670.9 | 3.124E-9 | 0 | 4482 | gtex_brain_putamen_basal |
| rs9975361 | 21 | 38450025 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 4499 | gtex_brain_putamen_basal |
| rs61701101 | 21 | 38450317 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 4791 | gtex_brain_putamen_basal |
| rs9975168 | 21 | 38450557 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 5031 | gtex_brain_putamen_basal |
| rs9977602 | 21 | 38450650 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 5124 | gtex_brain_putamen_basal |
| rs397776637 | 21 | 38450906 | TTC3 | ENSG00000182670.9 | 6.807E-10 | 0 | 5380 | gtex_brain_putamen_basal |
| rs7275582 | 21 | 38451130 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 5604 | gtex_brain_putamen_basal |
| rs7276917 | 21 | 38451334 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 5808 | gtex_brain_putamen_basal |
| rs9981706 | 21 | 38451970 | TTC3 | ENSG00000182670.9 | 3.397E-9 | 0 | 6444 | gtex_brain_putamen_basal |
| rs9981207 | 21 | 38451977 | TTC3 | ENSG00000182670.9 | 3.358E-9 | 0 | 6451 | gtex_brain_putamen_basal |
| rs9981136 | 21 | 38452022 | TTC3 | ENSG00000182670.9 | 2.946E-9 | 0 | 6496 | gtex_brain_putamen_basal |
| rs9981226 | 21 | 38452127 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 6601 | gtex_brain_putamen_basal |
| rs2187101 | 21 | 38452379 | TTC3 | ENSG00000182670.9 | 8.801E-10 | 0 | 6853 | gtex_brain_putamen_basal |
| rs2156076 | 21 | 38452634 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 7108 | gtex_brain_putamen_basal |
| rs4411798 | 21 | 38453183 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 7657 | gtex_brain_putamen_basal |
| rs4572679 | 21 | 38453227 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 7701 | gtex_brain_putamen_basal |
| rs10154032 | 21 | 38453459 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 7933 | gtex_brain_putamen_basal |
| rs10154036 | 21 | 38453510 | TTC3 | ENSG00000182670.9 | 2.586E-7 | 0 | 7984 | gtex_brain_putamen_basal |
| rs62223589 | 21 | 38453695 | TTC3 | ENSG00000182670.9 | 2.934E-9 | 0 | 8169 | gtex_brain_putamen_basal |
| rs9976621 | 21 | 38454339 | TTC3 | ENSG00000182670.9 | 3.057E-9 | 0 | 8813 | gtex_brain_putamen_basal |
| rs9977232 | 21 | 38454456 | TTC3 | ENSG00000182670.9 | 2.922E-9 | 0 | 8930 | gtex_brain_putamen_basal |
| rs11701556 | 21 | 38455153 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 9627 | gtex_brain_putamen_basal |
| rs2835574 | 21 | 38455324 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 9798 | gtex_brain_putamen_basal |
| rs2835575 | 21 | 38455936 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 10410 | gtex_brain_putamen_basal |
| rs28666643 | 21 | 38455999 | TTC3 | ENSG00000182670.9 | 7.259E-11 | 0 | 10473 | gtex_brain_putamen_basal |
| rs9974286 | 21 | 38456832 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 11306 | gtex_brain_putamen_basal |
| rs9974486 | 21 | 38457069 | TTC3 | ENSG00000182670.9 | 4.584E-9 | 0 | 11543 | gtex_brain_putamen_basal |
| rs9974798 | 21 | 38457272 | TTC3 | ENSG00000182670.9 | 3.262E-10 | 0 | 11746 | gtex_brain_putamen_basal |
| rs2835576 | 21 | 38457393 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 11867 | gtex_brain_putamen_basal |
| rs2835577 | 21 | 38457457 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 11931 | gtex_brain_putamen_basal |
| rs2835578 | 21 | 38457671 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 12145 | gtex_brain_putamen_basal |
| rs13050226 | 21 | 38457708 | TTC3 | ENSG00000182670.9 | 8.22E-11 | 0 | 12182 | gtex_brain_putamen_basal |
| rs2835579 | 21 | 38457965 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 12439 | gtex_brain_putamen_basal |
| rs2835582 | 21 | 38458773 | TTC3 | ENSG00000182670.9 | 3.064E-9 | 0 | 13247 | gtex_brain_putamen_basal |
| rs2835584 | 21 | 38460338 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 14812 | gtex_brain_putamen_basal |
| rs2835585 | 21 | 38460488 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 14962 | gtex_brain_putamen_basal |
| rs2835586 | 21 | 38461326 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 15800 | gtex_brain_putamen_basal |
| rs2835587 | 21 | 38461795 | TTC3 | ENSG00000182670.9 | 3.034E-9 | 0 | 16269 | gtex_brain_putamen_basal |
| rs9984861 | 21 | 38462028 | TTC3 | ENSG00000182670.9 | 5.596E-9 | 0 | 16502 | gtex_brain_putamen_basal |
| rs9984911 | 21 | 38462241 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 16715 | gtex_brain_putamen_basal |
| rs3787780 | 21 | 38462614 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 17088 | gtex_brain_putamen_basal |
| rs2835588 | 21 | 38462716 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 17190 | gtex_brain_putamen_basal |
| rs3787782 | 21 | 38462909 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 17383 | gtex_brain_putamen_basal |
| rs3787783 | 21 | 38462959 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 17433 | gtex_brain_putamen_basal |
| rs3827191 | 21 | 38463109 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 17583 | gtex_brain_putamen_basal |
| rs2835589 | 21 | 38463342 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 17816 | gtex_brain_putamen_basal |
| rs2835590 | 21 | 38463406 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 17880 | gtex_brain_putamen_basal |
| rs3787786 | 21 | 38463436 | TTC3 | ENSG00000182670.9 | 3.029E-9 | 0 | 17910 | gtex_brain_putamen_basal |
| rs3787787 | 21 | 38463452 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 17926 | gtex_brain_putamen_basal |
| rs9979811 | 21 | 38463967 | TTC3 | ENSG00000182670.9 | 1.363E-9 | 0 | 18441 | gtex_brain_putamen_basal |
| rs2835592 | 21 | 38464387 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 18861 | gtex_brain_putamen_basal |
| rs13050757 | 21 | 38465345 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 19819 | gtex_brain_putamen_basal |
| rs13046924 | 21 | 38465620 | TTC3 | ENSG00000182670.9 | 9.005E-9 | 0 | 20094 | gtex_brain_putamen_basal |
| rs2835593 | 21 | 38465873 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 20347 | gtex_brain_putamen_basal |
| rs2835594 | 21 | 38466064 | TTC3 | ENSG00000182670.9 | 3.086E-9 | 0 | 20538 | gtex_brain_putamen_basal |
| rs2835595 | 21 | 38466203 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 20677 | gtex_brain_putamen_basal |
| rs3753070 | 21 | 38466261 | TTC3 | ENSG00000182670.9 | 3.56E-9 | 0 | 20735 | gtex_brain_putamen_basal |
| rs200069136 | 21 | 38466261 | TTC3 | ENSG00000182670.9 | 9.001E-7 | 0 | 20735 | gtex_brain_putamen_basal |
| rs2835597 | 21 | 38466539 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 21013 | gtex_brain_putamen_basal |
| rs3753073 | 21 | 38466615 | TTC3 | ENSG00000182670.9 | 7.259E-11 | 0 | 21089 | gtex_brain_putamen_basal |
| rs2835598 | 21 | 38466669 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 21143 | gtex_brain_putamen_basal |
| rs2835599 | 21 | 38466937 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 21411 | gtex_brain_putamen_basal |
| rs2006941 | 21 | 38467616 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 22090 | gtex_brain_putamen_basal |
| rs2251161 | 21 | 38467857 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 22331 | gtex_brain_putamen_basal |
| rs2835600 | 21 | 38468958 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 23432 | gtex_brain_putamen_basal |
| rs2835601 | 21 | 38469017 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 23491 | gtex_brain_putamen_basal |
| rs2835602 | 21 | 38469069 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 23543 | gtex_brain_putamen_basal |
| rs7277657 | 21 | 38469523 | TTC3 | ENSG00000182670.9 | 2.944E-9 | 0 | 23997 | gtex_brain_putamen_basal |
| rs4817849 | 21 | 38469796 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 24270 | gtex_brain_putamen_basal |
| rs11911508 | 21 | 38470504 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 24978 | gtex_brain_putamen_basal |
| rs9977314 | 21 | 38471963 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 26437 | gtex_brain_putamen_basal |
| rs68084341 | 21 | 38474341 | TTC3 | ENSG00000182670.9 | 3.107E-9 | 0 | 28815 | gtex_brain_putamen_basal |
| rs34273703 | 21 | 38475019 | TTC3 | ENSG00000182670.9 | 2.057E-9 | 0 | 29493 | gtex_brain_putamen_basal |
| rs73201942 | 21 | 38475164 | TTC3 | ENSG00000182670.9 | 8.22E-11 | 0 | 29638 | gtex_brain_putamen_basal |
| rs59637309 | 21 | 38475398 | TTC3 | ENSG00000182670.9 | 2.952E-9 | 0 | 29872 | gtex_brain_putamen_basal |
| rs11088381 | 21 | 38478429 | TTC3 | ENSG00000182670.9 | 3.267E-9 | 0 | 32903 | gtex_brain_putamen_basal |
| rs9974374 | 21 | 38479885 | TTC3 | ENSG00000182670.9 | 9.344E-10 | 0 | 34359 | gtex_brain_putamen_basal |
| rs8130846 | 21 | 38480242 | TTC3 | ENSG00000182670.9 | 3.054E-9 | 0 | 34716 | gtex_brain_putamen_basal |
| rs8127148 | 21 | 38481292 | TTC3 | ENSG00000182670.9 | 3.262E-10 | 0 | 35766 | gtex_brain_putamen_basal |
| rs1793870 | 21 | 38481436 | TTC3 | ENSG00000182670.9 | 9.408E-11 | 0 | 35910 | gtex_brain_putamen_basal |
| rs8127182 | 21 | 38481505 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 35979 | gtex_brain_putamen_basal |
| rs111263176 | 21 | 38482304 | TTC3 | ENSG00000182670.9 | 5.59E-7 | 0 | 36778 | gtex_brain_putamen_basal |
| rs62223615 | 21 | 38484175 | TTC3 | ENSG00000182670.9 | 8.525E-8 | 0 | 38649 | gtex_brain_putamen_basal |
| rs150259029 | 21 | 38485178 | TTC3 | ENSG00000182670.9 | 3.583E-8 | 0 | 39652 | gtex_brain_putamen_basal |
| rs8131234 | 21 | 38487274 | TTC3 | ENSG00000182670.9 | 8.42E-9 | 0 | 41748 | gtex_brain_putamen_basal |
| rs4816560 | 21 | 38487561 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 42035 | gtex_brain_putamen_basal |
| rs397866600 | 21 | 38488922 | TTC3 | ENSG00000182670.9 | 9.133E-10 | 0 | 43396 | gtex_brain_putamen_basal |
| rs71198850 | 21 | 38489352 | TTC3 | ENSG00000182670.9 | 4.036E-7 | 0 | 43826 | gtex_brain_putamen_basal |
| rs4399800 | 21 | 38489478 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 43952 | gtex_brain_putamen_basal |
| rs2040341 | 21 | 38489753 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 44227 | gtex_brain_putamen_basal |
| rs7277150 | 21 | 38490006 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 44480 | gtex_brain_putamen_basal |
| rs2835605 | 21 | 38490734 | TTC3 | ENSG00000182670.9 | 3.039E-9 | 0 | 45208 | gtex_brain_putamen_basal |
| rs2835606 | 21 | 38490851 | TTC3 | ENSG00000182670.9 | 8.22E-11 | 0 | 45325 | gtex_brain_putamen_basal |
| rs1003719 | 21 | 38491095 | TTC3 | ENSG00000182670.9 | 2.207E-7 | 0 | 45569 | gtex_brain_putamen_basal |
| rs2835607 | 21 | 38491973 | TTC3 | ENSG00000182670.9 | 2.207E-7 | 0 | 46447 | gtex_brain_putamen_basal |
| rs2154536 | 21 | 38492147 | TTC3 | ENSG00000182670.9 | 2.207E-7 | 0 | 46621 | gtex_brain_putamen_basal |
| rs1003721 | 21 | 38492657 | TTC3 | ENSG00000182670.9 | 3.669E-8 | 0 | 47131 | gtex_brain_putamen_basal |
| rs2835608 | 21 | 38493455 | TTC3 | ENSG00000182670.9 | 2.207E-7 | 0 | 47929 | gtex_brain_putamen_basal |
| rs6517404 | 21 | 38494918 | TTC3 | ENSG00000182670.9 | 3.262E-10 | 0 | 49392 | gtex_brain_putamen_basal |
| rs2835613 | 21 | 38496883 | TTC3 | ENSG00000182670.9 | 1.043E-9 | 0 | 51357 | gtex_brain_putamen_basal |
| rs2835615 | 21 | 38497303 | TTC3 | ENSG00000182670.9 | 1.043E-9 | 0 | 51777 | gtex_brain_putamen_basal |
| rs10154113 | 21 | 38497490 | TTC3 | ENSG00000182670.9 | 9.389E-10 | 0 | 51964 | gtex_brain_putamen_basal |
| rs9981715 | 21 | 38499610 | TTC3 | ENSG00000182670.9 | 2.806E-10 | 0 | 54084 | gtex_brain_putamen_basal |
| rs12185870 | 21 | 38500689 | TTC3 | ENSG00000182670.9 | 1.935E-8 | 0 | 55163 | gtex_brain_putamen_basal |
| rs12185869 | 21 | 38500710 | TTC3 | ENSG00000182670.9 | 1.467E-8 | 0 | 55184 | gtex_brain_putamen_basal |
| rs9985082 | 21 | 38501021 | TTC3 | ENSG00000182670.9 | 3.542E-10 | 0 | 55495 | gtex_brain_putamen_basal |
| rs8129231 | 21 | 38501034 | TTC3 | ENSG00000182670.9 | 2.826E-10 | 0 | 55508 | gtex_brain_putamen_basal |
| rs2154537 | 21 | 38502012 | TTC3 | ENSG00000182670.9 | 1.766E-10 | 0 | 56486 | gtex_brain_putamen_basal |
| rs3787788 | 21 | 38502804 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 57278 | gtex_brain_putamen_basal |
| rs2000417 | 21 | 38502868 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 57342 | gtex_brain_putamen_basal |
| rs2835618 | 21 | 38503126 | TTC3 | ENSG00000182670.9 | 4.56E-11 | 0 | 57600 | gtex_brain_putamen_basal |
| rs4261789 | 21 | 38503762 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 58236 | gtex_brain_putamen_basal |
| rs10470177 | 21 | 38504653 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 59127 | gtex_brain_putamen_basal |
| rs2835619 | 21 | 38505380 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 59854 | gtex_brain_putamen_basal |
| rs2835620 | 21 | 38505581 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 60055 | gtex_brain_putamen_basal |
| rs7275984 | 21 | 38505696 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 60170 | gtex_brain_putamen_basal |
| rs3992 | 21 | 38505969 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 60443 | gtex_brain_putamen_basal |
| rs2252893 | 21 | 38507572 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 62046 | gtex_brain_putamen_basal |
| rs7282195 | 21 | 38508619 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 63093 | gtex_brain_putamen_basal |
| rs35199609 | 21 | 38510262 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 64736 | gtex_brain_putamen_basal |
| rs2835621 | 21 | 38510616 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 65090 | gtex_brain_putamen_basal |
| rs1133001 | 21 | 38512956 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 67430 | gtex_brain_putamen_basal |
| rs8134466 | 21 | 38516508 | TTC3 | ENSG00000182670.9 | 4.313E-10 | 0 | 70982 | gtex_brain_putamen_basal |
| rs56127106 | 21 | 38516549 | TTC3 | ENSG00000182670.9 | 1.253E-9 | 0 | 71023 | gtex_brain_putamen_basal |
| rs764175 | 21 | 38517058 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 71532 | gtex_brain_putamen_basal |
| rs2018521 | 21 | 38517264 | TTC3 | ENSG00000182670.9 | 2.098E-11 | 0 | 71738 | gtex_brain_putamen_basal |
| rs13046844 | 21 | 38517603 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 72077 | gtex_brain_putamen_basal |
| rs2252402 | 21 | 38520720 | TTC3 | ENSG00000182670.9 | 9.781E-12 | 0 | 75194 | gtex_brain_putamen_basal |
| rs2835629 | 21 | 38521660 | TTC3 | ENSG00000182670.9 | 2.819E-10 | 0 | 76134 | gtex_brain_putamen_basal |
| rs397705538 | 21 | 38521678 | TTC3 | ENSG00000182670.9 | 2.854E-10 | 0 | 76152 | gtex_brain_putamen_basal |
| rs2835630 | 21 | 38521842 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 76316 | gtex_brain_putamen_basal |
| rs2257091 | 21 | 38522618 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 77092 | gtex_brain_putamen_basal |
| rs3737540 | 21 | 38523266 | TTC3 | ENSG00000182670.9 | 7.666E-10 | 0 | 77740 | gtex_brain_putamen_basal |
| rs2835633 | 21 | 38525019 | TTC3 | ENSG00000182670.9 | 4.56E-11 | 0 | 79493 | gtex_brain_putamen_basal |
| rs1053808 | 21 | 38525356 | TTC3 | ENSG00000182670.9 | 4.56E-11 | 0 | 79830 | gtex_brain_putamen_basal |
| rs767998 | 21 | 38525652 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 80126 | gtex_brain_putamen_basal |
| rs2835634 | 21 | 38528270 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 82744 | gtex_brain_putamen_basal |
| rs201116403 | 21 | 38528341 | TTC3 | ENSG00000182670.9 | 3.118E-10 | 0 | 82815 | gtex_brain_putamen_basal |
| rs35023563 | 21 | 38528342 | TTC3 | ENSG00000182670.9 | 3.077E-10 | 0 | 82816 | gtex_brain_putamen_basal |
| rs71198854 | 21 | 38528508 | TTC3 | ENSG00000182670.9 | 9.752E-12 | 0 | 82982 | gtex_brain_putamen_basal |
| rs2187577 | 21 | 38533341 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 87815 | gtex_brain_putamen_basal |
| rs2298685 | 21 | 38533390 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 87864 | gtex_brain_putamen_basal |
| rs2835638 | 21 | 38534533 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 89007 | gtex_brain_putamen_basal |
| rs9978998 | 21 | 38535848 | TTC3 | ENSG00000182670.9 | 2.819E-10 | 0 | 90322 | gtex_brain_putamen_basal |
| rs2835639 | 21 | 38537016 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 91490 | gtex_brain_putamen_basal |
| rs2835640 | 21 | 38537380 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 91854 | gtex_brain_putamen_basal |
| rs2835642 | 21 | 38539066 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 93540 | gtex_brain_putamen_basal |
| rs2156077 | 21 | 38539357 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 93831 | gtex_brain_putamen_basal |
| rs2000413 | 21 | 38539718 | TTC3 | ENSG00000182670.9 | 6.691E-8 | 0 | 94192 | gtex_brain_putamen_basal |
| rs2000416 | 21 | 38540089 | TTC3 | ENSG00000182670.9 | 6.691E-8 | 0 | 94563 | gtex_brain_putamen_basal |
| rs58008706 | 21 | 38540506 | TTC3 | ENSG00000182670.9 | 6.691E-8 | 0 | 94980 | gtex_brain_putamen_basal |
| rs1981432 | 21 | 38541356 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 95830 | gtex_brain_putamen_basal |
| rs1981433 | 21 | 38542223 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 96697 | gtex_brain_putamen_basal |
| rs55992706 | 21 | 38542749 | TTC3 | ENSG00000182670.9 | 2.957E-10 | 0 | 97223 | gtex_brain_putamen_basal |
| rs55740803 | 21 | 38542761 | TTC3 | ENSG00000182670.9 | 2.957E-10 | 0 | 97235 | gtex_brain_putamen_basal |
| rs56268364 | 21 | 38542765 | TTC3 | ENSG00000182670.9 | 2.957E-10 | 0 | 97239 | gtex_brain_putamen_basal |
| rs2835644 | 21 | 38545610 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 100084 | gtex_brain_putamen_basal |
| rs2156078 | 21 | 38546473 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 100947 | gtex_brain_putamen_basal |
| rs2835646 | 21 | 38546574 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 101048 | gtex_brain_putamen_basal |
| rs2835647 | 21 | 38546773 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 101247 | gtex_brain_putamen_basal |
| rs71328561 | 21 | 38546806 | TTC3 | ENSG00000182670.9 | 2.821E-10 | 0 | 101280 | gtex_brain_putamen_basal |
| rs8131944 | 21 | 38547215 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 101689 | gtex_brain_putamen_basal |
| rs2040125 | 21 | 38549236 | TTC3 | ENSG00000182670.9 | 1.013E-11 | 0 | 103710 | gtex_brain_putamen_basal |
| rs2051398 | 21 | 38550258 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 104732 | gtex_brain_putamen_basal |
| rs8126491 | 21 | 38551219 | TTC3 | ENSG00000182670.9 | 2.844E-10 | 0 | 105693 | gtex_brain_putamen_basal |
| rs8126941 | 21 | 38551542 | TTC3 | ENSG00000182670.9 | 2.179E-9 | 0 | 106016 | gtex_brain_putamen_basal |
| rs8130643 | 21 | 38551715 | TTC3 | ENSG00000182670.9 | 2.838E-10 | 0 | 106189 | gtex_brain_putamen_basal |
| rs13046303 | 21 | 38551976 | TTC3 | ENSG00000182670.9 | 2.53E-11 | 0 | 106450 | gtex_brain_putamen_basal |
| rs8129942 | 21 | 38552070 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 106544 | gtex_brain_putamen_basal |
| rs8130069 | 21 | 38552116 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 106590 | gtex_brain_putamen_basal |
| rs2835649 | 21 | 38552230 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 106704 | gtex_brain_putamen_basal |
| rs8128387 | 21 | 38556787 | TTC3 | ENSG00000182670.9 | 2.8E-10 | 0 | 111261 | gtex_brain_putamen_basal |
| rs2835652 | 21 | 38557408 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 111882 | gtex_brain_putamen_basal |
| rs2835653 | 21 | 38558636 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 113110 | gtex_brain_putamen_basal |
| rs9980353 | 21 | 38558812 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 113286 | gtex_brain_putamen_basal |
| rs2251952 | 21 | 38559711 | TTC3 | ENSG00000182670.9 | 2.179E-9 | 0 | 114185 | gtex_brain_putamen_basal |
| rs6517405 | 21 | 38560334 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 114808 | gtex_brain_putamen_basal |
| rs397867287 | 21 | 38561385 | TTC3 | ENSG00000182670.9 | 1.742E-10 | 0 | 115859 | gtex_brain_putamen_basal |
| rs3787795 | 21 | 38562647 | TTC3 | ENSG00000182670.9 | 2.822E-10 | 0 | 117121 | gtex_brain_putamen_basal |
| rs2835657 | 21 | 38565064 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 119538 | gtex_brain_putamen_basal |
| rs2835658 | 21 | 38565201 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 119675 | gtex_brain_putamen_basal |
| rs9974494 | 21 | 38566566 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 121040 | gtex_brain_putamen_basal |
| rs2835659 | 21 | 38567902 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 122376 | gtex_brain_putamen_basal |
| rs7280251 | 21 | 38567911 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 122385 | gtex_brain_putamen_basal |
| rs1053966 | 21 | 38568009 | TTC3 | ENSG00000182670.9 | 9.329E-12 | 0 | 122483 | gtex_brain_putamen_basal |
| rs6579 | 21 | 38568308 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 122782 | gtex_brain_putamen_basal |
| rs762139 | 21 | 38568475 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 122949 | gtex_brain_putamen_basal |
| rs2835660 | 21 | 38568882 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 123356 | gtex_brain_putamen_basal |
| rs2835662 | 21 | 38568967 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 123441 | gtex_brain_putamen_basal |
| rs1034357 | 21 | 38571482 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 125956 | gtex_brain_putamen_basal |
| rs2835664 | 21 | 38573429 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 127903 | gtex_brain_putamen_basal |
| rs1053984 | 21 | 38574018 | TTC3 | ENSG00000182670.9 | 4.56E-11 | 0 | 128492 | gtex_brain_putamen_basal |
| rs35220333 | 21 | 38574673 | TTC3 | ENSG00000182670.9 | 5.323E-7 | 0 | 129147 | gtex_brain_putamen_basal |
| rs1063948 | 21 | 38574674 | TTC3 | ENSG00000182670.9 | 2.443E-9 | 0 | 129148 | gtex_brain_putamen_basal |
| rs1063949 | 21 | 38574675 | TTC3 | ENSG00000182670.9 | 1.828E-9 | 0 | 129149 | gtex_brain_putamen_basal |
| rs9982 | 21 | 38574680 | TTC3 | ENSG00000182670.9 | 4.611E-11 | 0 | 129154 | gtex_brain_putamen_basal |
| rs2032063 | 21 | 38576657 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 131131 | gtex_brain_putamen_basal |
| rs6517406 | 21 | 38577817 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 132291 | gtex_brain_putamen_basal |
| rs7276711 | 21 | 38578189 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 132663 | gtex_brain_putamen_basal |
| rs7276569 | 21 | 38578207 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 132681 | gtex_brain_putamen_basal |
| rs2212742 | 21 | 38578685 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 133159 | gtex_brain_putamen_basal |
| rs2835667 | 21 | 38579914 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 134388 | gtex_brain_putamen_basal |
| rs2835668 | 21 | 38580151 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 134625 | gtex_brain_putamen_basal |
| rs7277820 | 21 | 38580309 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 134783 | gtex_brain_putamen_basal |
| rs2835670 | 21 | 38581114 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 135588 | gtex_brain_putamen_basal |
| rs2835671 | 21 | 38581125 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 135599 | gtex_brain_putamen_basal |
| rs2835672 | 21 | 38581234 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 135708 | gtex_brain_putamen_basal |
| rs11356622 | 21 | 38581422 | TTC3 | ENSG00000182670.9 | 2.902E-10 | 0 | 135896 | gtex_brain_putamen_basal |
| rs2835674 | 21 | 38581522 | TTC3 | ENSG00000182670.9 | 2.839E-10 | 0 | 135996 | gtex_brain_putamen_basal |
| rs2246285 | 21 | 38582431 | TTC3 | ENSG00000182670.9 | 1.773E-10 | 0 | 136905 | gtex_brain_putamen_basal |
| rs2835675 | 21 | 38582815 | TTC3 | ENSG00000182670.9 | 1.064E-9 | 0 | 137289 | gtex_brain_putamen_basal |
| rs34520132 | 21 | 38583133 | TTC3 | ENSG00000182670.9 | 5.029E-9 | 0 | 137607 | gtex_brain_putamen_basal |
| rs9982429 | 21 | 38586334 | TTC3 | ENSG00000182670.9 | 1.451E-8 | 0 | 140808 | gtex_brain_putamen_basal |
| rs9982431 | 21 | 38586339 | TTC3 | ENSG00000182670.9 | 3.182E-8 | 0 | 140813 | gtex_brain_putamen_basal |
| rs200994614 | 21 | 38586845 | TTC3 | ENSG00000182670.9 | 2.804E-11 | 0 | 141319 | gtex_brain_putamen_basal |
| rs9976501 | 21 | 38587837 | TTC3 | ENSG00000182670.9 | 2.729E-10 | 0 | 142311 | gtex_brain_putamen_basal |
| rs9976360 | 21 | 38587860 | TTC3 | ENSG00000182670.9 | 2.459E-10 | 0 | 142334 | gtex_brain_putamen_basal |
| rs3035179 | 21 | 38588281 | TTC3 | ENSG00000182670.9 | 2.773E-10 | 0 | 142755 | gtex_brain_putamen_basal |
| rs9636914 | 21 | 38589732 | TTC3 | ENSG00000182670.9 | 6.992E-12 | 0 | 144206 | gtex_brain_putamen_basal |
| rs2835676 | 21 | 38591311 | TTC3 | ENSG00000182670.9 | 1.418E-6 | 0 | 145785 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN | 634 | 384 | All SZGR 2.0 genes in this pathway |
| ONKEN UVEAL MELANOMA UP | 783 | 507 | All SZGR 2.0 genes in this pathway |
| BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER DN | 169 | 118 | All SZGR 2.0 genes in this pathway |
| SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP | 408 | 247 | All SZGR 2.0 genes in this pathway |
| TURASHVILI BREAST CARCINOMA DUCTAL VS LOBULAR UP | 21 | 14 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS UP | 473 | 314 | All SZGR 2.0 genes in this pathway |
| THUM SYSTOLIC HEART FAILURE DN | 244 | 147 | All SZGR 2.0 genes in this pathway |
| CHARAFE BREAST CANCER LUMINAL VS BASAL UP | 380 | 215 | All SZGR 2.0 genes in this pathway |
| BASAKI YBX1 TARGETS DN | 384 | 230 | All SZGR 2.0 genes in this pathway |
| WANG LMO4 TARGETS UP | 372 | 227 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN MLL SIGNATURE 1 DN | 242 | 165 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN MLL SIGNATURE 2 DN | 281 | 186 | All SZGR 2.0 genes in this pathway |
| TIEN INTESTINE PROBIOTICS 24HR DN | 214 | 133 | All SZGR 2.0 genes in this pathway |
| RODRIGUES THYROID CARCINOMA ANAPLASTIC UP | 722 | 443 | All SZGR 2.0 genes in this pathway |
| HAHTOLA MYCOSIS FUNGOIDES CD4 DN | 116 | 71 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| GAUSSMANN MLL AF4 FUSION TARGETS G UP | 238 | 135 | All SZGR 2.0 genes in this pathway |
| BERENJENO TRANSFORMED BY RHOA DN | 394 | 258 | All SZGR 2.0 genes in this pathway |
| EBAUER TARGETS OF PAX3 FOXO1 FUSION UP | 207 | 128 | All SZGR 2.0 genes in this pathway |
| MATTIOLI MULTIPLE MYELOMA SUBGROUPS | 16 | 7 | All SZGR 2.0 genes in this pathway |
| MOHANKUMAR TLX1 TARGETS UP | 414 | 287 | All SZGR 2.0 genes in this pathway |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | 584 | 395 | All SZGR 2.0 genes in this pathway |
| FALVELLA SMOKERS WITH LUNG CANCER | 80 | 52 | All SZGR 2.0 genes in this pathway |
| PARK HSC AND MULTIPOTENT PROGENITORS | 50 | 33 | All SZGR 2.0 genes in this pathway |
| SESTO RESPONSE TO UV C8 | 72 | 56 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE DN | 1237 | 837 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT DN | 165 | 106 | All SZGR 2.0 genes in this pathway |
| COATES MACROPHAGE M1 VS M2 UP | 81 | 52 | All SZGR 2.0 genes in this pathway |
| MITSIADES RESPONSE TO APLIDIN DN | 249 | 165 | All SZGR 2.0 genes in this pathway |
| ZHANG BREAST CANCER PROGENITORS UP | 425 | 253 | All SZGR 2.0 genes in this pathway |
| ZHANG BREAST CANCER PROGENITORS DN | 145 | 93 | All SZGR 2.0 genes in this pathway |
| CADWELL ATG16L1 TARGETS DN | 70 | 43 | All SZGR 2.0 genes in this pathway |
| WANG TUMOR INVASIVENESS DN | 210 | 128 | All SZGR 2.0 genes in this pathway |
| BOYAULT LIVER CANCER SUBCLASS G1 UP | 113 | 70 | All SZGR 2.0 genes in this pathway |
| YAGI AML WITH T 8 21 TRANSLOCATION | 368 | 247 | All SZGR 2.0 genes in this pathway |
| HOSHIDA LIVER CANCER SUBCLASS S2 | 115 | 74 | All SZGR 2.0 genes in this pathway |
| CAIRO LIVER DEVELOPMENT UP | 166 | 105 | All SZGR 2.0 genes in this pathway |
| WONG ADULT TISSUE STEM MODULE | 721 | 492 | All SZGR 2.0 genes in this pathway |
| LI INDUCED T TO NATURAL KILLER DN | 116 | 83 | All SZGR 2.0 genes in this pathway |
| KIM ALL DISORDERS CALB1 CORR UP | 548 | 370 | All SZGR 2.0 genes in this pathway |
| VERHAAK GLIOBLASTOMA PRONEURAL | 177 | 132 | All SZGR 2.0 genes in this pathway |
| HIRSCH CELLULAR TRANSFORMATION SIGNATURE DN | 103 | 67 | All SZGR 2.0 genes in this pathway |
| CHICAS RB1 TARGETS SENESCENT | 572 | 352 | All SZGR 2.0 genes in this pathway |
| CHICAS RB1 TARGETS GROWING | 243 | 155 | All SZGR 2.0 genes in this pathway |
| LI DCP2 BOUND MRNA | 89 | 57 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |