SZGR2

Summary ?

GeneID	7276
Symbol	TTR
Synonyms	CTS\|CTS1\|HEL111\|HsT2651\|PALB\|TBPA
Description	transthyretin
Reference	MIM:176300\|HGNC:HGNC:12405\|Ensembl:ENSG00000118271\|HPRD:01447\|Vega:OTTHUMG00000131984
Gene type	protein-coding
Map location	18q12.1
Pascal p-value	0.075
Sherlock p-value	0.864
Fetal beta	0.923
eGene	Myers' cis & trans

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenics,schizophrenias	Click to show details
Network	Shortest path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 1.3333

Section I. Genetics and epigenetics annotation

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	qvalue	eQTL type
rs734994	chr1	30796504	TTR	7276	0.14	trans
rs17091285	chr1	71957915	TTR	7276	0.17	trans
rs11162132	chr1	76833107	TTR	7276	2.341E-4	trans
rs6688662	chr1	76842132	TTR	7276	2.702E-6	trans
rs421660	chr1	91633187	TTR	7276	0.14	trans
snp_a-1965574		0	TTR	7276	0.06	trans
rs1891733	chr1	164807829	TTR	7276	7.315E-5	trans
rs12118136	chr1	164812580	TTR	7276	5.331E-4	trans
rs17392895	chr1	164814782	TTR	7276	2.307E-4	trans
rs512189	chr1	182632586	TTR	7276	0	trans
rs16823145	chr1	184397914	TTR	7276	0.11	trans
rs16849110	chr1	201567374	TTR	7276	0.03	trans
rs17163777	chr1	223468731	TTR	7276	0.15	trans
rs6666913	chr1	237092144	TTR	7276	4.156E-8	trans
rs7528464	chr1	246272686	TTR	7276	0.03	trans
rs1377421	chr2	35213051	TTR	7276	0.08	trans
rs10209546	chr2	53408320	TTR	7276	2.155E-4	trans
rs3755119	chr2	53957339	TTR	7276	0.01	trans
rs13401483	chr2	84219167	TTR	7276	0.09	trans
rs260675	chr2	109600118	TTR	7276	0	trans
rs7596511	chr2	120010898	TTR	7276	4.693E-4	trans
rs7574824	chr2	130696073	TTR	7276	0.06	trans
rs10176716	chr2	151596595	TTR	7276	0.02	trans
rs10195263	chr2	151725791	TTR	7276	0.07	trans
rs12694629	chr2	157312146	TTR	7276	0.17	trans
rs10515928	chr2	160074898	TTR	7276	0.1	trans
rs9287785	chr2	160075008	TTR	7276	0.1	trans
rs10490004	chr2	160076139	TTR	7276	0.1	trans
rs11903200	chr2	160076308	TTR	7276	0.1	trans
rs2241023	chr2	160081335	TTR	7276	0.1	trans
rs10490003	chr2	160082889	TTR	7276	0.1	trans
rs10189317	chr2	160123106	TTR	7276	0.1	trans
rs8179587	chr2	160187588	TTR	7276	0.18	trans
rs13035414	chr2	166304918	TTR	7276	0.15	trans
rs7600169	chr2	167080978	TTR	7276	0.07	trans
rs7589313	chr2	174771910	TTR	7276	0.15	trans
rs4453654	chr2	189185130	TTR	7276	0.01	trans
rs1983539	chr3	9736740	TTR	7276	0.07	trans
snp_a-2312022		0	TTR	7276	0.07	trans
rs17015415	chr3	24933888	TTR	7276	0.08	trans
rs7646474	chr3	46011068	TTR	7276	0.01	trans
rs11923953	chr3	64365756	TTR	7276	0	trans
rs6548978	chr3	68139529	TTR	7276	0.03	trans
rs17011179	chr3	73501887	TTR	7276	0.04	trans
rs7609917	chr3	76094301	TTR	7276	3.598E-7	trans
rs2324466	chr3	76100753	TTR	7276	4.359E-12	trans
rs17013713	chr3	76105150	TTR	7276	1.824E-13	trans
rs17013724	chr3	76107684	TTR	7276	4.359E-12	trans
rs301930	chr3	97348309	TTR	7276	0.06	trans
rs2705554	chr3	112273545	TTR	7276	0.07	trans
rs4312656	chr3	115157721	TTR	7276	0.03	trans
rs16859029	chr3	146759514	TTR	7276	0.17	trans
rs16831155	chr3	173574763	TTR	7276	0.01	trans
rs9882442	chr3	173644484	TTR	7276	3.282E-4	trans
rs4686772	chr3	186126448	TTR	7276	0.04	trans
rs1403709	chr3	187472811	TTR	7276	0.04	trans
rs10015205	chr4	26144278	TTR	7276	0.06	trans
rs16991886	chr4	36048970	TTR	7276	0	trans
rs12646252		0	TTR	7276	0.01	trans
rs17148160	chr4	70974564	TTR	7276	0.19	trans
rs1389042	chr4	82973241	TTR	7276	0.03	trans
rs11734196	chr4	102796071	TTR	7276	0.03	trans
rs10212684	chr4	102822506	TTR	7276	0.03	trans
rs17007390	chr4	124705927	TTR	7276	0.01	trans
rs11937178	chr4	148847598	TTR	7276	0.02	trans
rs11934409	chr4	148848884	TTR	7276	0.02	trans
rs2605050	chr4	180362144	TTR	7276	0.01	trans
rs4301163	chr4	187861271	TTR	7276	0.08	trans
rs9986296	chr5	3199318	TTR	7276	0	trans
rs16875617	chr5	5483721	TTR	7276	0.13	trans
rs16875618	chr5	5484079	TTR	7276	0.13	trans
rs16875619	chr5	5487310	TTR	7276	0.13	trans
rs4702271	chr5	5491289	TTR	7276	0.13	trans
rs2937812	chr5	5540693	TTR	7276	0.18	trans
rs16876290	chr5	5790694	TTR	7276	0.16	trans
rs10755251	chr5	31789357	TTR	7276	0.16	trans
rs2455248	chr5	36478729	TTR	7276	9.987E-4	trans
rs2648734	chr5	52068572	TTR	7276	0	trans
rs6897533	chr5	72660099	TTR	7276	0.17	trans
rs12658469	chr5	72670113	TTR	7276	0.16	trans
rs920385	chr5	124490714	TTR	7276	0.04	trans
rs2895773	chr5	148114635	TTR	7276	0.03	trans
rs17077791	chr5	176616523	TTR	7276	0.14	trans
rs2281351	chr6	187343	TTR	7276	0.08	trans
rs9396617	chr6	15924214	TTR	7276	0	trans
rs726836	chr6	25843925	TTR	7276	0.05	trans
rs16899778	chr6	27390149	TTR	7276	0.15	trans
rs7740062	chr6	27705597	TTR	7276	0.01	trans
rs200470	chr6	27762186	TTR	7276	5.129E-4	trans
rs201005	chr6	27804159	TTR	7276	0.01	trans
rs200955	chr6	27839311	TTR	7276	0.01	trans
rs200959	chr6	27842046	TTR	7276	0.01	trans
rs839777	chr6	27909656	TTR	7276	0	trans
rs149898	chr6	27958071	TTR	7276	0	trans
rs156741	chr6	27962383	TTR	7276	0.01	trans
rs156742	chr6	27963191	TTR	7276	0	trans
rs175955	chr6	28059733	TTR	7276	0	trans
rs1225593	chr6	28150518	TTR	7276	0	trans
rs16894180	chr6	28628465	TTR	7276	0.09	trans
rs3130602	chr6	32972206	TTR	7276	0.01	trans
rs16895035	chr6	34839096	TTR	7276	0.13	trans
rs9380466	chr6	34869223	TTR	7276	0.15	trans
rs195749	chr6	37253745	TTR	7276	0.01	trans
rs4435942	chr6	37694937	TTR	7276	0.02	trans
rs16896683	chr6	43687846	TTR	7276	0.03	trans
rs9463383	chr6	48260637	TTR	7276	0.14	trans
rs16875134	chr6	85489519	TTR	7276	0.02	trans
rs16875178	chr6	85516099	TTR	7276	0.11	trans
rs7762250	chr6	144475063	TTR	7276	0.05	trans
rs3735131	chr7	2962292	TTR	7276	0.06	trans
rs7808764	chr7	10297264	TTR	7276	0.08	trans
rs1005524	chr7	20596813	TTR	7276	0.18	trans
rs17145334	chr7	21808409	TTR	7276	0.09	trans
rs17148638	chr7	24065071	TTR	7276	0.03	trans
rs895578	chr7	35410694	TTR	7276	0.02	trans
rs340406	chr7	35418631	TTR	7276	0.16	trans
rs2197617	chr7	35504198	TTR	7276	0.16	trans
rs2013491	chr7	91946015	TTR	7276	0.05	trans
rs992435	chr7	97050802	TTR	7276	0.01	trans
rs7810149	chr7	111899363	TTR	7276	0.06	trans
rs1047551	chr7	111983277	TTR	7276	0.14	trans
rs1528356	chr7	121121454	TTR	7276	0.02	trans
rs12532261	chr7	132264028	TTR	7276	0.02	trans
rs12533690	chr7	132265977	TTR	7276	0.01	trans
rs6952992	chr7	139421473	TTR	7276	0.15	trans
rs7810706	chr7	150831288	TTR	7276	1.663E-4	trans
rs11769541	chr7	154373157	TTR	7276	0.01	trans
rs4504596	chr8	11111891	TTR	7276	0.14	trans
rs8190856	chr8	18079123	TTR	7276	0.18	trans
rs16920368	chr8	55392852	TTR	7276	6.068E-4	trans
rs16927318	chr8	62365911	TTR	7276	3.254E-7	trans
rs348150	chr8	73371619	TTR	7276	0	trans
rs16938220	chr8	73377940	TTR	7276	0.01	trans
rs7843769	chr8	83608406	TTR	7276	8.283E-4	trans
rs7830923	chr8	83608478	TTR	7276	8.283E-4	trans
rs16910790	chr8	83621808	TTR	7276	2.313E-4	trans
rs16910793	chr8	83621841	TTR	7276	8.283E-4	trans
rs16910802	chr8	83622265	TTR	7276	8.283E-4	trans
rs16910804	chr8	83622540	TTR	7276	0	trans
rs1969215	chr8	108644706	TTR	7276	0.18	trans
rs16904520	chr8	132774255	TTR	7276	0.06	trans
rs12547258	chr8	133456995	TTR	7276	0.05	trans
rs1448721	chr8	136924784	TTR	7276	0.14	trans
rs16908622	chr8	139231604	TTR	7276	0.05	trans
rs4545144	chr8	139689307	TTR	7276	8.061E-4	trans
rs3780045		0	TTR	7276	0.17	trans
rs10815658	chr9	7709422	TTR	7276	1.43E-4	trans
rs1410387	chr9	89359203	TTR	7276	0.11	trans
rs180038	chr9	101514415	TTR	7276	0.02	trans
rs4742740	chr9	101524552	TTR	7276	0	trans
rs4743277	chr9	101557528	TTR	7276	0	trans
rs10119434	chr9	110944789	TTR	7276	7.613E-4	trans
rs10983187	chr9	119238934	TTR	7276	0.01	trans
rs2448377	chr10	274223	TTR	7276	0.2	trans
rs11251091	chr10	2249852	TTR	7276	0.03	trans
rs11007809	chr10	30209705	TTR	7276	0.1	trans
rs11238503	chr10	43781090	TTR	7276	0.13	trans
rs16916915	chr10	63785368	TTR	7276	0.16	trans
rs7906330	chr10	87372192	TTR	7276	0.13	trans
rs11193467	chr10	109217296	TTR	7276	0.16	trans
rs7920992	chr10	130402940	TTR	7276	0.08	trans
rs6578423	chr11	3969443	TTR	7276	0.01	trans
rs16929438	chr11	4104006	TTR	7276	0.05	trans
rs16907878	chr11	10518250	TTR	7276	0.11	trans
rs17233214	chr11	21367388	TTR	7276	0.03	trans
rs11823843	chr11	21376537	TTR	7276	0.18	trans
rs16911034	chr11	23302320	TTR	7276	0.03	trans
rs10734372	chr11	26090747	TTR	7276	0.03	trans
rs12224887	chr11	37400374	TTR	7276	0.04	trans
rs11034154	chr11	37481053	TTR	7276	0.17	trans
rs1002405	chr11	85572958	TTR	7276	0.08	trans
rs11569358	chr12	6553503	TTR	7276	0.11	trans
rs7311343	chr12	21228780	TTR	7276	0.06	trans
rs11177887	chr12	41093631	TTR	7276	0.07	trans
rs12305552	chr12	41797385	TTR	7276	0.11	trans
rs2069410	chr12	56364644	TTR	7276	4.62E-14	trans
rs17120736	chr12	58785277	TTR	7276	0.1	trans
rs11115597	chr12	83509142	TTR	7276	2.005E-4	trans
rs10746278	chr12	83789575	TTR	7276	0	trans
rs7979024	chr12	84506011	TTR	7276	0.19	trans
rs11105124	chr12	89375908	TTR	7276	0.07	trans
rs17837122	chr12	92660211	TTR	7276	0.01	trans
rs7972610	chr12	93486183	TTR	7276	0	trans
rs10859541	chr12	94010186	TTR	7276	0.03	trans
rs17021407	chr12	94013807	TTR	7276	0.13	trans
rs17031683	chr12	102005385	TTR	7276	0.14	trans
rs825045	chr12	102045030	TTR	7276	0.01	trans
rs6539020	chr12	102308189	TTR	7276	0.15	trans
rs4770243	chr13	22662276	TTR	7276	0.06	trans
rs1885898	chr13	22676828	TTR	7276	0.18	trans
rs1885900	chr13	22676939	TTR	7276	0.18	trans
rs1125957	chr13	22693170	TTR	7276	0.18	trans
rs17078563	chr13	23864835	TTR	7276	6.011E-4	trans
rs9670212	chr13	29070572	TTR	7276	0	trans
rs17053321	chr13	36577034	TTR	7276	0.16	trans
rs17834315	chr13	37991091	TTR	7276	3.047E-7	trans
rs17072833	chr13	49914392	TTR	7276	0.19	trans
rs575555	chr13	52437620	TTR	7276	0.01	trans
rs343134	chr13	60204988	TTR	7276	0.01	trans
rs11841288	chr13	60215833	TTR	7276	1.56E-4	trans
rs987035	chr13	106274330	TTR	7276	0.08	trans
rs16967008	chr13	106287437	TTR	7276	0.06	trans
rs16975617	chr13	110867407	TTR	7276	0.12	trans
rs10498433	chr14	52289530	TTR	7276	0	trans
rs17091014	chr14	56562713	TTR	7276	2.379E-4	trans
rs10483833	chr14	71165243	TTR	7276	0.04	trans
rs1642278	chr14	87273027	TTR	7276	0.09	trans
rs1743505	chr14	96143407	TTR	7276	0.01	trans
rs6576402	chr15	25310439	TTR	7276	0.16	trans
rs16946329	chr15	63324362	TTR	7276	0.01	trans
rs16946913	chr15	63653889	TTR	7276	0.13	trans
rs17694187	chr15	91881259	TTR	7276	0.02	trans
rs17524193	chr15	93222971	TTR	7276	0.07	trans
rs920567	chr15	98248480	TTR	7276	0.06	trans
rs931891	chr15	98293206	TTR	7276	0.03	trans
rs6598553	chr15	99339208	TTR	7276	0.08	trans
rs17634236	chr16	5067148	TTR	7276	0.01	trans
rs17142983	chr16	7294508	TTR	7276	0.03	trans
rs8056710	chr16	7447629	TTR	7276	0.01	trans
rs16972025	chr16	19461881	TTR	7276	0.14	trans
rs1557515	chr16	19462965	TTR	7276	0.12	trans
rs12596831	chr16	23385256	TTR	7276	0.03	trans
rs17666993	chr16	72146665	TTR	7276	0.03	trans
rs17667053	chr16	72147430	TTR	7276	0.01	trans
rs8051077	chr16	75036432	TTR	7276	0.16	trans
rs935931	chr16	81208821	TTR	7276	0	trans
rs1391765	chr17	8297465	TTR	7276	0.12	trans
rs8077034	chr17	12145884	TTR	7276	0.14	trans
snp_a-2072200		0	TTR	7276	0.07	trans
rs4796760	chr17	40178214	TTR	7276	0.09	trans
rs4799294	chr18	38002283	TTR	7276	0.19	trans
rs17798004	chr18	70665382	TTR	7276	0.01	trans
rs17736134	chr18	70665805	TTR	7276	3.988E-4	trans
rs2469060	chr18	70673106	TTR	7276	3.988E-4	trans
rs2469009	chr18	70713334	TTR	7276	1.007E-4	trans
rs9962412	chr18	73427437	TTR	7276	0.13	trans
rs9965745	chr18	73429162	TTR	7276	0.12	trans
rs1943200	chr18	73462540	TTR	7276	0.18	trans
rs166727	chr19	30470254	TTR	7276	0.11	trans
rs8110995	chr19	40863841	TTR	7276	0.01	trans
rs2288529	chr19	55665688	TTR	7276	0.08	trans
rs12461195	chr19	55688575	TTR	7276	0.19	trans
rs1022791	chr20	10730770	TTR	7276	0.16	trans
rs6514759		0	TTR	7276	0.05	trans
rs409642	chr20	54250273	TTR	7276	0.03	trans
snp_a-2019049		0	TTR	7276	0.07	trans
rs2835891	chr21	39056226	TTR	7276	0.2	trans
rs7275460	chr21	41447057	TTR	7276	0.03	trans
rs16993260	chr22	34300774	TTR	7276	0.12	trans
rs16993271	chr22	34307850	TTR	7276	0	trans
rs140059	chr22	37977417	TTR	7276	0.07	trans
rs17003586	chr22	43667457	TTR	7276	9.781E-4	trans
rs2269667	chr22	43699291	TTR	7276	0.03	trans
rs6008434	chr22	46665669	TTR	7276	0.08	trans
rs6007794	chr22	46685016	TTR	7276	0.04	trans
rs7290732	chr22	46691902	TTR	7276	0	trans
rs5961111	chrX	54659538	TTR	7276	0.1	trans
rs5920627	chrX	97385064	TTR	7276	0.03	trans
snp_a-2027825		0	TTR	7276	6.667E-5	trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
COMMD9	0.81	0.80
PRKAG1	0.80	0.76
GABARAPL2	0.80	0.80
COPS4	0.79	0.75
ARPC4	0.79	0.76
UBE2D2	0.78	0.77
ATP5B	0.78	0.75
UBE2E1	0.77	0.77
FAM54B	0.77	0.73
POP4	0.77	0.73

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AF347015.18	-0.64	-0.62
AF347015.2	-0.62	-0.53
AF347015.8	-0.62	-0.53
AF347015.26	-0.61	-0.54
MT-ATP8	-0.57	-0.51
AF347015.15	-0.57	-0.49
MT-CYB	-0.57	-0.49
AC100783.1	-0.57	-0.57
MT-CO2	-0.56	-0.47
AC016705.1	-0.55	-0.58

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005179	hormone activity	IEA		-
GO:0005496	steroid binding	IEA		-
GO:0019841	retinol binding	IEA		-
GO:0016918	retinal binding	IEA		-
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0006810	transport	NAS		10841549
GO:0006590	thyroid hormone generation	IEA		-
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005576	extracellular region	NAS		14718574

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ATF4	CREB-2 \| CREB2 \| TAXREB67 \| TXREB	activating transcription factor 4 (tax-responsive enhancer element B67)	Two-hybrid	BioGRID	16189514
C7orf20	CEE \| CGI-20	chromosome 7 open reading frame 20	Two-hybrid	BioGRID	16169070
CHD3	Mi-2a \| Mi2-ALPHA \| ZFH	chromodomain helicase DNA binding protein 3	Two-hybrid	BioGRID	16169070
DDR1	CAK \| CD167 \| DDR \| EDDR1 \| MCK10 \| NEP \| NTRK4 \| PTK3 \| PTK3A \| RTK6 \| TRKE	discoidin domain receptor tyrosine kinase 1	Two-hybrid	BioGRID	16169070
EEF1A1	CCS-3 \| CCS3 \| EEF-1 \| EEF1A \| EF-Tu \| EF1A \| FLJ25721 \| GRAF-1EF \| HNGC:16303 \| LENG7 \| MGC102687 \| MGC131894 \| MGC16224 \| PTI1 \| eEF1A-1	eukaryotic translation elongation factor 1 alpha 1	Two-hybrid	BioGRID	16169070
FEZ1	-	fasciculation and elongation protein zeta 1 (zygin I)	Two-hybrid	BioGRID	16169070
HNRNPH3	2H9 \| FLJ34092 \| HNRPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	Two-hybrid	BioGRID	16169070
HSPG2	PLC \| PRCAN \| SJA \| SJS \| SJS1	heparan sulfate proteoglycan 2	-	HPRD,BioGRID	9307034
IKBKAP	DKFZp781H1425 \| DYS \| ELP1 \| FD \| FLJ12497 \| IKAP \| IKI3 \| TOT1	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	Two-hybrid	BioGRID	16169070
LRP2	DBS \| gp330	low density lipoprotein-related protein 2	-	HPRD	10982792
MARK3	CTAK1 \| KP78 \| PAR1A	MAP/microtubule affinity-regulating kinase 3	Two-hybrid	BioGRID	16169070
PHYHIP	DYRK1AP3 \| KIAA0273 \| PAHX-AP \| PAHXAP1	phytanoyl-CoA 2-hydroxylase interacting protein	Two-hybrid	BioGRID	16169070
RBP4	-	retinol binding protein 4, plasma	-	HPRD,BioGRID	574085 \|8089102 \|11853533 \|12593674
SETDB1	ESET \| KG1T \| KIAA0067 \| KMT1E	SET domain, bifurcated 1	Two-hybrid	BioGRID	16169070
TTR	HsT2651 \| PALB \| TBPA	transthyretin	Co-crystal Structure	BioGRID	11243784
VIM	FLJ36605	vimentin	Two-hybrid	BioGRID	16169070

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
PID HNF3B PATHWAY	45	37	All SZGR 2.0 genes in this pathway
REACTOME AMYLOIDS	83	63	All SZGR 2.0 genes in this pathway
SABATES COLORECTAL ADENOMA DN	291	176	All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER DN	514	319	All SZGR 2.0 genes in this pathway
KONDO HYPOXIA	8	6	All SZGR 2.0 genes in this pathway
CERVERA SDHB TARGETS 2	114	76	All SZGR 2.0 genes in this pathway
ASTON MAJOR DEPRESSIVE DISORDER UP	49	36	All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS	882	572	All SZGR 2.0 genes in this pathway
WONG IFNA2 RESISTANCE DN	34	20	All SZGR 2.0 genes in this pathway
HSIAO LIVER SPECIFIC GENES	244	154	All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR	544	307	All SZGR 2.0 genes in this pathway
YAMAZAKI TCEB3 TARGETS UP	175	116	All SZGR 2.0 genes in this pathway
TUOMISTO TUMOR SUPPRESSION BY COL13A1 DN	17	11	All SZGR 2.0 genes in this pathway
LEIN CHOROID PLEXUS MARKERS	103	61	All SZGR 2.0 genes in this pathway
LEE LIVER CANCER	49	29	All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 2D DN	64	35	All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER DN	540	340	All SZGR 2.0 genes in this pathway
BOCHKIS FOXA2 TARGETS	425	261	All SZGR 2.0 genes in this pathway
LABBE WNT3A TARGETS DN	97	53	All SZGR 2.0 genes in this pathway
LABBE TARGETS OF TGFB1 AND WNT3A DN	108	68	All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS DN	70	43	All SZGR 2.0 genes in this pathway
YAUCH HEDGEHOG SIGNALING PARACRINE DN	264	159	All SZGR 2.0 genes in this pathway
SASAI TARGETS OF CXCR6 AND PTCH1 UP	13	9	All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SURVIVAL DN	113	76	All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP	504	321	All SZGR 2.0 genes in this pathway
VANDESLUIS COMMD1 TARGETS GROUP 4 UP	19	12	All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS DN	109	71	All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL UP	289	184	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-141/200a	78	84	m8	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	78	84	m8	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.

Gene Page: TTR