Gene Page: UROS
Summary ?
| GeneID | 7390 |
| Symbol | UROS |
| Synonyms | UROIIIS |
| Description | uroporphyrinogen III synthase |
| Reference | MIM:606938|HGNC:HGNC:12592|Ensembl:ENSG00000188690|HPRD:06087|Vega:OTTHUMG00000019236 |
| Gene type | protein-coding |
| Map location | 10q25.2-q26.3 |
| Pascal p-value | 0.014 |
| Sherlock p-value | 0.882 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_IIA | Genome scan meta-analysis (All samples) | Psr: 0.03487 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10901424 | 10 | 127460952 | UROS | ENSG00000188690.8 | 8.649E-8 | 0 | 50865 | gtex_brain_ba24 |
| rs28381281 | 10 | 127462833 | UROS | ENSG00000188690.8 | 1.04E-6 | 0 | 48984 | gtex_brain_ba24 |
| rs28745891 | 10 | 127465866 | UROS | ENSG00000188690.8 | 7.423E-8 | 0 | 45951 | gtex_brain_ba24 |
| rs7907787 | 10 | 127467292 | UROS | ENSG00000188690.8 | 2.663E-13 | 0 | 44525 | gtex_brain_ba24 |
| rs7919631 | 10 | 127467300 | UROS | ENSG00000188690.8 | 2.663E-13 | 0 | 44517 | gtex_brain_ba24 |
| rs7918694 | 10 | 127467328 | UROS | ENSG00000188690.8 | 2.663E-13 | 0 | 44489 | gtex_brain_ba24 |
| rs7907930 | 10 | 127467650 | UROS | ENSG00000188690.8 | 2.66E-13 | 0 | 44167 | gtex_brain_ba24 |
| rs11244642 | 10 | 127467664 | UROS | ENSG00000188690.8 | 2.66E-13 | 0 | 44153 | gtex_brain_ba24 |
| rs10901426 | 10 | 127467697 | UROS | ENSG00000188690.8 | 2.66E-13 | 0 | 44120 | gtex_brain_ba24 |
| rs10901427 | 10 | 127467748 | UROS | ENSG00000188690.8 | 1.56E-15 | 0 | 44069 | gtex_brain_ba24 |
| rs10901428 | 10 | 127467987 | UROS | ENSG00000188690.8 | 2.684E-13 | 0 | 43830 | gtex_brain_ba24 |
| rs10901429 | 10 | 127468458 | UROS | ENSG00000188690.8 | 4.699E-12 | 0 | 43359 | gtex_brain_ba24 |
| rs11244644 | 10 | 127469566 | UROS | ENSG00000188690.8 | 2.663E-13 | 0 | 42251 | gtex_brain_ba24 |
| rs10901431 | 10 | 127474375 | UROS | ENSG00000188690.8 | 1.124E-15 | 0 | 37442 | gtex_brain_ba24 |
| rs10751531 | 10 | 127474657 | UROS | ENSG00000188690.8 | 7.651E-19 | 0 | 37160 | gtex_brain_ba24 |
| rs10751532 | 10 | 127474707 | UROS | ENSG00000188690.8 | 6.838E-19 | 0 | 37110 | gtex_brain_ba24 |
| rs11244646 | 10 | 127475151 | UROS | ENSG00000188690.8 | 1.124E-15 | 0 | 36666 | gtex_brain_ba24 |
| rs11244647 | 10 | 127475169 | UROS | ENSG00000188690.8 | 1.124E-15 | 0 | 36648 | gtex_brain_ba24 |
| rs9633753 | 10 | 127475792 | UROS | ENSG00000188690.8 | 5.215E-17 | 0 | 36025 | gtex_brain_ba24 |
| rs10901432 | 10 | 127476323 | UROS | ENSG00000188690.8 | 5.215E-17 | 0 | 35494 | gtex_brain_ba24 |
| rs2281958 | 10 | 127476874 | UROS | ENSG00000188690.8 | 5.215E-17 | 0 | 34943 | gtex_brain_ba24 |
| rs10794021 | 10 | 127478594 | UROS | ENSG00000188690.8 | 4.956E-17 | 0 | 33223 | gtex_brain_ba24 |
| rs10794022 | 10 | 127479115 | UROS | ENSG00000188690.8 | 5.195E-17 | 0 | 32702 | gtex_brain_ba24 |
| rs10901435 | 10 | 127481908 | UROS | ENSG00000188690.8 | 8.507E-14 | 0 | 29909 | gtex_brain_ba24 |
| rs11244655 | 10 | 127482137 | UROS | ENSG00000188690.8 | 2.48E-17 | 0 | 29680 | gtex_brain_ba24 |
| rs34569988 | 10 | 127482435 | UROS | ENSG00000188690.8 | 4.011E-8 | 0 | 29382 | gtex_brain_ba24 |
| rs41315014 | 10 | 127482764 | UROS | ENSG00000188690.8 | 2.072E-12 | 0 | 29053 | gtex_brain_ba24 |
| rs2149019 | 10 | 127482950 | UROS | ENSG00000188690.8 | 5.396E-16 | 0 | 28867 | gtex_brain_ba24 |
| rs3740179 | 10 | 127483573 | UROS | ENSG00000188690.8 | 5.396E-16 | 0 | 28244 | gtex_brain_ba24 |
| rs10751533 | 10 | 127483964 | UROS | ENSG00000188690.8 | 6.672E-15 | 0 | 27853 | gtex_brain_ba24 |
| rs7342100 | 10 | 127484203 | UROS | ENSG00000188690.8 | 6.672E-15 | 0 | 27614 | gtex_brain_ba24 |
| rs2281957 | 10 | 127484234 | UROS | ENSG00000188690.8 | 6.672E-15 | 0 | 27583 | gtex_brain_ba24 |
| rs2281956 | 10 | 127484543 | UROS | ENSG00000188690.8 | 5.422E-16 | 0 | 27274 | gtex_brain_ba24 |
| rs2281955 | 10 | 127484617 | UROS | ENSG00000188690.8 | 5.438E-16 | 0 | 27200 | gtex_brain_ba24 |
| rs2281954 | 10 | 127484653 | UROS | ENSG00000188690.8 | 5.374E-16 | 0 | 27164 | gtex_brain_ba24 |
| rs1571278 | 10 | 127485254 | UROS | ENSG00000188690.8 | 5.604E-16 | 0 | 26563 | gtex_brain_ba24 |
| rs34128376 | 10 | 127486341 | UROS | ENSG00000188690.8 | 6.922E-16 | 0 | 25476 | gtex_brain_ba24 |
| rs10901436 | 10 | 127486429 | UROS | ENSG00000188690.8 | 2.269E-14 | 0 | 25388 | gtex_brain_ba24 |
| rs10901437 | 10 | 127486885 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 24932 | gtex_brain_ba24 |
| rs11244656 | 10 | 127487171 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 24646 | gtex_brain_ba24 |
| rs10901438 | 10 | 127487529 | UROS | ENSG00000188690.8 | 6.669E-15 | 0 | 24288 | gtex_brain_ba24 |
| rs8181322 | 10 | 127487773 | UROS | ENSG00000188690.8 | 5.416E-16 | 0 | 24044 | gtex_brain_ba24 |
| rs11244657 | 10 | 127487800 | UROS | ENSG00000188690.8 | 2.269E-14 | 0 | 24017 | gtex_brain_ba24 |
| rs11244658 | 10 | 127487815 | UROS | ENSG00000188690.8 | 3.592E-17 | 0 | 24002 | gtex_brain_ba24 |
| rs8181289 | 10 | 127488927 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 22890 | gtex_brain_ba24 |
| rs10901439 | 10 | 127490689 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 21128 | gtex_brain_ba24 |
| rs3814624 | 10 | 127491165 | UROS | ENSG00000188690.8 | 9.479E-15 | 0 | 20652 | gtex_brain_ba24 |
| rs74366862 | 10 | 127491732 | UROS | ENSG00000188690.8 | 2.834E-16 | 0 | 20085 | gtex_brain_ba24 |
| rs10901440 | 10 | 127491896 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 19921 | gtex_brain_ba24 |
| rs10901441 | 10 | 127491906 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 19911 | gtex_brain_ba24 |
| rs947582 | 10 | 127495354 | UROS | ENSG00000188690.8 | 1.047E-16 | 0 | 16463 | gtex_brain_ba24 |
| rs10510149 | 10 | 127495807 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 16010 | gtex_brain_ba24 |
| rs10901442 | 10 | 127496359 | UROS | ENSG00000188690.8 | 6.868E-19 | 0 | 15458 | gtex_brain_ba24 |
| rs10794024 | 10 | 127496608 | UROS | ENSG00000188690.8 | 6.868E-19 | 0 | 15209 | gtex_brain_ba24 |
| rs10901443 | 10 | 127498368 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 13449 | gtex_brain_ba24 |
| rs10794025 | 10 | 127498555 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 13262 | gtex_brain_ba24 |
| rs9651505 | 10 | 127500279 | UROS | ENSG00000188690.8 | 7.851E-15 | 0 | 11538 | gtex_brain_ba24 |
| rs9651507 | 10 | 127500490 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 11327 | gtex_brain_ba24 |
| rs10901444 | 10 | 127500718 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 11099 | gtex_brain_ba24 |
| rs10901446 | 10 | 127502347 | UROS | ENSG00000188690.8 | 6.868E-19 | 0 | 9470 | gtex_brain_ba24 |
| rs10159841 | 10 | 127502834 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 8983 | gtex_brain_ba24 |
| rs10159660 | 10 | 127503213 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 8604 | gtex_brain_ba24 |
| rs10751534 | 10 | 127503943 | UROS | ENSG00000188690.8 | 1.052E-16 | 0 | 7874 | gtex_brain_ba24 |
| rs10794026 | 10 | 127504019 | UROS | ENSG00000188690.8 | 4.894E-16 | 0 | 7798 | gtex_brain_ba24 |
| rs11244664 | 10 | 127504389 | UROS | ENSG00000188690.8 | 5.229E-18 | 0 | 7428 | gtex_brain_ba24 |
| rs10901447 | 10 | 127505863 | UROS | ENSG00000188690.8 | 4.571E-14 | 0 | 5954 | gtex_brain_ba24 |
| rs201375511 | 10 | 127507556 | UROS | ENSG00000188690.8 | 2.401E-14 | 0 | 4261 | gtex_brain_ba24 |
| rs10901448 | 10 | 127507647 | UROS | ENSG00000188690.8 | 9.611E-19 | 0 | 4170 | gtex_brain_ba24 |
| rs11599714 | 10 | 127508725 | UROS | ENSG00000188690.8 | 1.09E-16 | 0 | 3092 | gtex_brain_ba24 |
| rs10901450 | 10 | 127509294 | UROS | ENSG00000188690.8 | 7.194E-19 | 0 | 2523 | gtex_brain_ba24 |
| rs4256900 | 10 | 127511756 | UROS | ENSG00000188690.8 | 7.468E-19 | 0 | 61 | gtex_brain_ba24 |
| rs4385801 | 10 | 127511790 | UROS | ENSG00000188690.8 | 7.598E-19 | 0 | 27 | gtex_brain_ba24 |
| rs10159992 | 10 | 127515069 | UROS | ENSG00000188690.8 | 2.715E-15 | 0 | -3252 | gtex_brain_ba24 |
| rs11244667 | 10 | 127518538 | UROS | ENSG00000188690.8 | 1.164E-12 | 0 | -6721 | gtex_brain_ba24 |
| rs2366040 | 10 | 127520429 | UROS | ENSG00000188690.8 | 6.131E-11 | 0 | -8612 | gtex_brain_ba24 |
| rs3740206 | 10 | 127522572 | UROS | ENSG00000188690.8 | 8.985E-14 | 0 | -10755 | gtex_brain_ba24 |
| rs2185740 | 10 | 127522988 | UROS | ENSG00000188690.8 | 1.047E-11 | 0 | -11171 | gtex_brain_ba24 |
| rs1891360 | 10 | 127524168 | UROS | ENSG00000188690.8 | 2.888E-7 | 0 | -12351 | gtex_brain_ba24 |
| rs4075326 | 10 | 127524612 | UROS | ENSG00000188690.8 | 1.842E-13 | 0 | -12795 | gtex_brain_ba24 |
| rs7320 | 10 | 127525072 | UROS | ENSG00000188690.8 | 8.18E-12 | 0 | -13255 | gtex_brain_ba24 |
| rs3781058 | 10 | 127528267 | UROS | ENSG00000188690.8 | 6.011E-11 | 0 | -16450 | gtex_brain_ba24 |
| rs3208565 | 10 | 127530325 | UROS | ENSG00000188690.8 | 2.181E-14 | 0 | -18508 | gtex_brain_ba24 |
| rs12049644 | 10 | 127531514 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -19697 | gtex_brain_ba24 |
| rs11244668 | 10 | 127531959 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -20142 | gtex_brain_ba24 |
| rs11244669 | 10 | 127532782 | UROS | ENSG00000188690.8 | 1.42E-6 | 0 | -20965 | gtex_brain_ba24 |
| rs12356233 | 10 | 127534930 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -23113 | gtex_brain_ba24 |
| rs10901454 | 10 | 127536267 | UROS | ENSG00000188690.8 | 2.205E-14 | 0 | -24450 | gtex_brain_ba24 |
| rs10794027 | 10 | 127536562 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -24745 | gtex_brain_ba24 |
| rs11244671 | 10 | 127538973 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -27156 | gtex_brain_ba24 |
| rs10901455 | 10 | 127539196 | UROS | ENSG00000188690.8 | 2.125E-10 | 0 | -27379 | gtex_brain_ba24 |
| rs10901456 | 10 | 127545418 | UROS | ENSG00000188690.8 | 4.87E-17 | 0 | -33601 | gtex_brain_ba24 |
| rs10794028 | 10 | 127550491 | UROS | ENSG00000188690.8 | 9.225E-12 | 0 | -38674 | gtex_brain_ba24 |
| rs11244677 | 10 | 127553359 | UROS | ENSG00000188690.8 | 2.25E-14 | 0 | -41542 | gtex_brain_ba24 |
| rs11244678 | 10 | 127554534 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -42717 | gtex_brain_ba24 |
| rs10794030 | 10 | 127562375 | UROS | ENSG00000188690.8 | 2.181E-14 | 0 | -50558 | gtex_brain_ba24 |
| rs10901457 | 10 | 127563509 | UROS | ENSG00000188690.8 | 9.336E-12 | 0 | -51692 | gtex_brain_ba24 |
| rs2366050 | 10 | 127564306 | UROS | ENSG00000188690.8 | 5.539E-12 | 0 | -52489 | gtex_brain_ba24 |
| rs10794031 | 10 | 127565320 | UROS | ENSG00000188690.8 | 5.656E-14 | 0 | -53503 | gtex_brain_ba24 |
| rs11244686 | 10 | 127568260 | UROS | ENSG00000188690.8 | 6.436E-12 | 0 | -56443 | gtex_brain_ba24 |
| rs2366053 | 10 | 127571426 | UROS | ENSG00000188690.8 | 5.807E-14 | 0 | -59609 | gtex_brain_ba24 |
| rs10901458 | 10 | 127572773 | UROS | ENSG00000188690.8 | 5.715E-12 | 0 | -60956 | gtex_brain_ba24 |
| rs10751535 | 10 | 127589202 | UROS | ENSG00000188690.8 | 1.494E-9 | 0 | -77385 | gtex_brain_ba24 |
| rs10794036 | 10 | 127590349 | UROS | ENSG00000188690.8 | 1.13E-10 | 0 | -78532 | gtex_brain_ba24 |
| rs61871956 | 10 | 127590661 | UROS | ENSG00000188690.8 | 8.636E-12 | 0 | -78844 | gtex_brain_ba24 |
| rs7474918 | 10 | 127592385 | UROS | ENSG00000188690.8 | 3.621E-7 | 0 | -80568 | gtex_brain_ba24 |
| rs10794037 | 10 | 127596105 | UROS | ENSG00000188690.8 | 1.488E-6 | 0 | -84288 | gtex_brain_ba24 |
| rs10901465 | 10 | 127596596 | UROS | ENSG00000188690.8 | 2.223E-11 | 0 | -84779 | gtex_brain_ba24 |
| rs4615938 | 10 | 127598226 | UROS | ENSG00000188690.8 | 1.377E-11 | 0 | -86409 | gtex_brain_ba24 |
| rs10794038 | 10 | 127600013 | UROS | ENSG00000188690.8 | 2.048E-11 | 0 | -88196 | gtex_brain_ba24 |
| rs10901466 | 10 | 127601214 | UROS | ENSG00000188690.8 | 2.62E-10 | 0 | -89397 | gtex_brain_ba24 |
| rs12256020 | 10 | 127603156 | UROS | ENSG00000188690.8 | 1.767E-9 | 0 | -91339 | gtex_brain_ba24 |
| rs10794039 | 10 | 127606560 | UROS | ENSG00000188690.8 | 1.617E-10 | 0 | -94743 | gtex_brain_ba24 |
| rs10901468 | 10 | 127607262 | UROS | ENSG00000188690.8 | 1.605E-9 | 0 | -95445 | gtex_brain_ba24 |
| rs11244701 | 10 | 127607827 | UROS | ENSG00000188690.8 | 1.612E-11 | 0 | -96010 | gtex_brain_ba24 |
| rs10794040 | 10 | 127614273 | UROS | ENSG00000188690.8 | 4.142E-12 | 0 | -102456 | gtex_brain_ba24 |
| rs10901470 | 10 | 127615817 | UROS | ENSG00000188690.8 | 2.245E-11 | 0 | -104000 | gtex_brain_ba24 |
| rs11244703 | 10 | 127616324 | UROS | ENSG00000188690.8 | 6.452E-8 | 0 | -104507 | gtex_brain_ba24 |
| rs11244704 | 10 | 127616826 | UROS | ENSG00000188690.8 | 1.54E-13 | 0 | -105009 | gtex_brain_ba24 |
| rs10901471 | 10 | 127617020 | UROS | ENSG00000188690.8 | 3.667E-13 | 0 | -105203 | gtex_brain_ba24 |
| rs144488289 | 10 | 127617030 | UROS | ENSG00000188690.8 | 1.454E-13 | 0 | -105213 | gtex_brain_ba24 |
| rs12359733 | 10 | 127620582 | UROS | ENSG00000188690.8 | 2.849E-13 | 0 | -108765 | gtex_brain_ba24 |
| rs1949313 | 10 | 127621532 | UROS | ENSG00000188690.8 | 2.849E-13 | 0 | -109715 | gtex_brain_ba24 |
| rs11244713 | 10 | 127633638 | UROS | ENSG00000188690.8 | 1.072E-11 | 0 | -121821 | gtex_brain_ba24 |
| rs10901473 | 10 | 127634125 | UROS | ENSG00000188690.8 | 2.106E-12 | 0 | -122308 | gtex_brain_ba24 |
| rs11244714 | 10 | 127639907 | UROS | ENSG00000188690.8 | 1.418E-13 | 0 | -128090 | gtex_brain_ba24 |
| rs10794042 | 10 | 127641756 | UROS | ENSG00000188690.8 | 2.71E-12 | 0 | -129939 | gtex_brain_ba24 |
| rs10901475 | 10 | 127642064 | UROS | ENSG00000188690.8 | 2.71E-12 | 0 | -130247 | gtex_brain_ba24 |
| rs4403725 | 10 | 127642276 | UROS | ENSG00000188690.8 | 2.71E-12 | 0 | -130459 | gtex_brain_ba24 |
| rs10901476 | 10 | 127642617 | UROS | ENSG00000188690.8 | 2.911E-13 | 0 | -130800 | gtex_brain_ba24 |
| rs11244716 | 10 | 127642986 | UROS | ENSG00000188690.8 | 2.911E-13 | 0 | -131169 | gtex_brain_ba24 |
| rs11244717 | 10 | 127643296 | UROS | ENSG00000188690.8 | 2.934E-12 | 0 | -131479 | gtex_brain_ba24 |
| rs11244719 | 10 | 127643599 | UROS | ENSG00000188690.8 | 1.947E-10 | 0 | -131782 | gtex_brain_ba24 |
| rs61870940 | 10 | 127643900 | UROS | ENSG00000188690.8 | 2.921E-13 | 0 | -132083 | gtex_brain_ba24 |
| rs11244720 | 10 | 127644783 | UROS | ENSG00000188690.8 | 1.605E-13 | 0 | -132966 | gtex_brain_ba24 |
| rs10901477 | 10 | 127644935 | UROS | ENSG00000188690.8 | 2.92E-13 | 0 | -133118 | gtex_brain_ba24 |
| rs11244722 | 10 | 127646360 | UROS | ENSG00000188690.8 | 2.911E-13 | 0 | -134543 | gtex_brain_ba24 |
| rs11244724 | 10 | 127646444 | UROS | ENSG00000188690.8 | 2.911E-13 | 0 | -134627 | gtex_brain_ba24 |
| rs11244725 | 10 | 127647134 | UROS | ENSG00000188690.8 | 2.911E-13 | 0 | -135317 | gtex_brain_ba24 |
| rs10901481 | 10 | 127647705 | UROS | ENSG00000188690.8 | 2.837E-13 | 0 | -135888 | gtex_brain_ba24 |
| rs10901482 | 10 | 127647737 | UROS | ENSG00000188690.8 | 2.911E-13 | 0 | -135920 | gtex_brain_ba24 |
| rs398114890 | 10 | 127647810 | UROS | ENSG00000188690.8 | 3.635E-12 | 0 | -135993 | gtex_brain_ba24 |
| rs10901483 | 10 | 127649011 | UROS | ENSG00000188690.8 | 2.917E-13 | 0 | -137194 | gtex_brain_ba24 |
| rs11244727 | 10 | 127649149 | UROS | ENSG00000188690.8 | 2.917E-13 | 0 | -137332 | gtex_brain_ba24 |
| rs11244728 | 10 | 127649188 | UROS | ENSG00000188690.8 | 3.47E-13 | 0 | -137371 | gtex_brain_ba24 |
| rs11244729 | 10 | 127649193 | UROS | ENSG00000188690.8 | 7.097E-13 | 0 | -137376 | gtex_brain_ba24 |
| rs11244732 | 10 | 127650710 | UROS | ENSG00000188690.8 | 1.958E-7 | 0 | -138893 | gtex_brain_ba24 |
| rs11244733 | 10 | 127651741 | UROS | ENSG00000188690.8 | 8.902E-14 | 0 | -139924 | gtex_brain_ba24 |
| rs10458780 | 10 | 127652028 | UROS | ENSG00000188690.8 | 2.075E-8 | 0 | -140211 | gtex_brain_ba24 |
| rs76339414 | 10 | 127652326 | UROS | ENSG00000188690.8 | 7.376E-14 | 0 | -140509 | gtex_brain_ba24 |
| rs7358157 | 10 | 127653081 | UROS | ENSG00000188690.8 | 7.373E-14 | 0 | -141264 | gtex_brain_ba24 |
| rs10458781 | 10 | 127653583 | UROS | ENSG00000188690.8 | 8.912E-13 | 0 | -141766 | gtex_brain_ba24 |
| rs10794045 | 10 | 127653940 | UROS | ENSG00000188690.8 | 7.373E-14 | 0 | -142123 | gtex_brain_ba24 |
| rs10794046 | 10 | 127654536 | UROS | ENSG00000188690.8 | 7.252E-11 | 0 | -142719 | gtex_brain_ba24 |
| rs10901484 | 10 | 127654672 | UROS | ENSG00000188690.8 | 7.37E-14 | 0 | -142855 | gtex_brain_ba24 |
| rs10901486 | 10 | 127655852 | UROS | ENSG00000188690.8 | 7.699E-14 | 0 | -144035 | gtex_brain_ba24 |
| rs10901487 | 10 | 127655861 | UROS | ENSG00000188690.8 | 7.713E-14 | 0 | -144044 | gtex_brain_ba24 |
| rs11244734 | 10 | 127656114 | UROS | ENSG00000188690.8 | 8.204E-14 | 0 | -144297 | gtex_brain_ba24 |
| rs10901488 | 10 | 127657666 | UROS | ENSG00000188690.8 | 2.048E-13 | 0 | -145849 | gtex_brain_ba24 |
| rs11244736 | 10 | 127658731 | UROS | ENSG00000188690.8 | 4.231E-9 | 0 | -146914 | gtex_brain_ba24 |
| rs11244737 | 10 | 127658748 | UROS | ENSG00000188690.8 | 3.024E-11 | 0 | -146931 | gtex_brain_ba24 |
| rs61870942 | 10 | 127659131 | UROS | ENSG00000188690.8 | 8.664E-12 | 0 | -147314 | gtex_brain_ba24 |
| rs11244738 | 10 | 127660351 | UROS | ENSG00000188690.8 | 5.736E-9 | 0 | -148534 | gtex_brain_ba24 |
| rs7099772 | 10 | 127729222 | UROS | ENSG00000188690.8 | 5.604E-8 | 0 | -217405 | gtex_brain_ba24 |
| rs10901424 | 10 | 127460952 | UROS | ENSG00000188690.8 | 3.852E-8 | 0 | 50865 | gtex_brain_putamen_basal |
| rs28381281 | 10 | 127462833 | UROS | ENSG00000188690.8 | 5.389E-7 | 0 | 48984 | gtex_brain_putamen_basal |
| rs28745891 | 10 | 127465866 | UROS | ENSG00000188690.8 | 1.507E-8 | 0 | 45951 | gtex_brain_putamen_basal |
| rs7907787 | 10 | 127467292 | UROS | ENSG00000188690.8 | 5.042E-14 | 0 | 44525 | gtex_brain_putamen_basal |
| rs7919631 | 10 | 127467300 | UROS | ENSG00000188690.8 | 4.968E-14 | 0 | 44517 | gtex_brain_putamen_basal |
| rs7918694 | 10 | 127467328 | UROS | ENSG00000188690.8 | 4.934E-14 | 0 | 44489 | gtex_brain_putamen_basal |
| rs7907930 | 10 | 127467650 | UROS | ENSG00000188690.8 | 4.705E-14 | 0 | 44167 | gtex_brain_putamen_basal |
| rs11244642 | 10 | 127467664 | UROS | ENSG00000188690.8 | 4.577E-14 | 0 | 44153 | gtex_brain_putamen_basal |
| rs10901426 | 10 | 127467697 | UROS | ENSG00000188690.8 | 3.934E-14 | 0 | 44120 | gtex_brain_putamen_basal |
| rs10901427 | 10 | 127467748 | UROS | ENSG00000188690.8 | 2.686E-16 | 0 | 44069 | gtex_brain_putamen_basal |
| rs10901428 | 10 | 127467987 | UROS | ENSG00000188690.8 | 1.138E-11 | 0 | 43830 | gtex_brain_putamen_basal |
| rs10901429 | 10 | 127468458 | UROS | ENSG00000188690.8 | 6.441E-11 | 0 | 43359 | gtex_brain_putamen_basal |
| rs11244644 | 10 | 127469566 | UROS | ENSG00000188690.8 | 2.777E-14 | 0 | 42251 | gtex_brain_putamen_basal |
| rs10901431 | 10 | 127474375 | UROS | ENSG00000188690.8 | 1.167E-19 | 0 | 37442 | gtex_brain_putamen_basal |
| rs10751531 | 10 | 127474657 | UROS | ENSG00000188690.8 | 1.656E-19 | 0 | 37160 | gtex_brain_putamen_basal |
| rs10751532 | 10 | 127474707 | UROS | ENSG00000188690.8 | 1.226E-19 | 0 | 37110 | gtex_brain_putamen_basal |
| rs11244646 | 10 | 127475151 | UROS | ENSG00000188690.8 | 1.167E-19 | 0 | 36666 | gtex_brain_putamen_basal |
| rs11244647 | 10 | 127475169 | UROS | ENSG00000188690.8 | 1.167E-19 | 0 | 36648 | gtex_brain_putamen_basal |
| rs9633753 | 10 | 127475792 | UROS | ENSG00000188690.8 | 1.715E-18 | 0 | 36025 | gtex_brain_putamen_basal |
| rs10901432 | 10 | 127476323 | UROS | ENSG00000188690.8 | 2.55E-16 | 0 | 35494 | gtex_brain_putamen_basal |
| rs2281958 | 10 | 127476874 | UROS | ENSG00000188690.8 | 1.719E-18 | 0 | 34943 | gtex_brain_putamen_basal |
| rs10794021 | 10 | 127478594 | UROS | ENSG00000188690.8 | 1.712E-18 | 0 | 33223 | gtex_brain_putamen_basal |
| rs10794022 | 10 | 127479115 | UROS | ENSG00000188690.8 | 1.715E-18 | 0 | 32702 | gtex_brain_putamen_basal |
| rs10901435 | 10 | 127481908 | UROS | ENSG00000188690.8 | 4.257E-12 | 0 | 29909 | gtex_brain_putamen_basal |
| rs11244655 | 10 | 127482137 | UROS | ENSG00000188690.8 | 2.612E-18 | 0 | 29680 | gtex_brain_putamen_basal |
| rs34569988 | 10 | 127482435 | UROS | ENSG00000188690.8 | 2.832E-9 | 0 | 29382 | gtex_brain_putamen_basal |
| rs41315014 | 10 | 127482764 | UROS | ENSG00000188690.8 | 4.708E-15 | 0 | 29053 | gtex_brain_putamen_basal |
| rs2149019 | 10 | 127482950 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 28867 | gtex_brain_putamen_basal |
| rs3740179 | 10 | 127483573 | UROS | ENSG00000188690.8 | 1.196E-16 | 0 | 28244 | gtex_brain_putamen_basal |
| rs10751533 | 10 | 127483964 | UROS | ENSG00000188690.8 | 1.385E-17 | 0 | 27853 | gtex_brain_putamen_basal |
| rs7342100 | 10 | 127484203 | UROS | ENSG00000188690.8 | 1.315E-17 | 0 | 27614 | gtex_brain_putamen_basal |
| rs2281957 | 10 | 127484234 | UROS | ENSG00000188690.8 | 1.315E-17 | 0 | 27583 | gtex_brain_putamen_basal |
| rs2281956 | 10 | 127484543 | UROS | ENSG00000188690.8 | 1.172E-16 | 0 | 27274 | gtex_brain_putamen_basal |
| rs2281955 | 10 | 127484617 | UROS | ENSG00000188690.8 | 1.173E-16 | 0 | 27200 | gtex_brain_putamen_basal |
| rs2281954 | 10 | 127484653 | UROS | ENSG00000188690.8 | 1.126E-16 | 0 | 27164 | gtex_brain_putamen_basal |
| rs1571278 | 10 | 127485254 | UROS | ENSG00000188690.8 | 2.847E-17 | 0 | 26563 | gtex_brain_putamen_basal |
| rs34128376 | 10 | 127486341 | UROS | ENSG00000188690.8 | 1.809E-15 | 0 | 25476 | gtex_brain_putamen_basal |
| rs10901436 | 10 | 127486429 | UROS | ENSG00000188690.8 | 3.359E-16 | 0 | 25388 | gtex_brain_putamen_basal |
| rs10901437 | 10 | 127486885 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 24932 | gtex_brain_putamen_basal |
| rs11244656 | 10 | 127487171 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 24646 | gtex_brain_putamen_basal |
| rs10901438 | 10 | 127487529 | UROS | ENSG00000188690.8 | 1.315E-17 | 0 | 24288 | gtex_brain_putamen_basal |
| rs8181322 | 10 | 127487773 | UROS | ENSG00000188690.8 | 2.051E-15 | 0 | 24044 | gtex_brain_putamen_basal |
| rs11244657 | 10 | 127487800 | UROS | ENSG00000188690.8 | 3.359E-16 | 0 | 24017 | gtex_brain_putamen_basal |
| rs11244658 | 10 | 127487815 | UROS | ENSG00000188690.8 | 3.359E-16 | 0 | 24002 | gtex_brain_putamen_basal |
| rs8181289 | 10 | 127488927 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 22890 | gtex_brain_putamen_basal |
| rs10901439 | 10 | 127490689 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 21128 | gtex_brain_putamen_basal |
| rs3814624 | 10 | 127491165 | UROS | ENSG00000188690.8 | 1.411E-13 | 0 | 20652 | gtex_brain_putamen_basal |
| rs74366862 | 10 | 127491732 | UROS | ENSG00000188690.8 | 2.018E-15 | 0 | 20085 | gtex_brain_putamen_basal |
| rs10901440 | 10 | 127491896 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 19921 | gtex_brain_putamen_basal |
| rs10901441 | 10 | 127491906 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 19911 | gtex_brain_putamen_basal |
| rs947582 | 10 | 127495354 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 16463 | gtex_brain_putamen_basal |
| rs10510149 | 10 | 127495807 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 16010 | gtex_brain_putamen_basal |
| rs10901442 | 10 | 127496359 | UROS | ENSG00000188690.8 | 1.559E-20 | 0 | 15458 | gtex_brain_putamen_basal |
| rs10794024 | 10 | 127496608 | UROS | ENSG00000188690.8 | 1.559E-20 | 0 | 15209 | gtex_brain_putamen_basal |
| rs10901443 | 10 | 127498368 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 13449 | gtex_brain_putamen_basal |
| rs10794025 | 10 | 127498555 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 13262 | gtex_brain_putamen_basal |
| rs9651505 | 10 | 127500279 | UROS | ENSG00000188690.8 | 4.865E-18 | 0 | 11538 | gtex_brain_putamen_basal |
| rs9651507 | 10 | 127500490 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 11327 | gtex_brain_putamen_basal |
| rs10901444 | 10 | 127500718 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 11099 | gtex_brain_putamen_basal |
| rs10901446 | 10 | 127502347 | UROS | ENSG00000188690.8 | 1.559E-20 | 0 | 9470 | gtex_brain_putamen_basal |
| rs10159841 | 10 | 127502834 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 8983 | gtex_brain_putamen_basal |
| rs10159660 | 10 | 127503213 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 8604 | gtex_brain_putamen_basal |
| rs10751534 | 10 | 127503943 | UROS | ENSG00000188690.8 | 4.205E-17 | 0 | 7874 | gtex_brain_putamen_basal |
| rs10794026 | 10 | 127504019 | UROS | ENSG00000188690.8 | 1.991E-15 | 0 | 7798 | gtex_brain_putamen_basal |
| rs11244664 | 10 | 127504389 | UROS | ENSG00000188690.8 | 2.195E-18 | 0 | 7428 | gtex_brain_putamen_basal |
| rs10901447 | 10 | 127505863 | UROS | ENSG00000188690.8 | 2.009E-11 | 0 | 5954 | gtex_brain_putamen_basal |
| rs201375511 | 10 | 127507556 | UROS | ENSG00000188690.8 | 4.826E-16 | 0 | 4261 | gtex_brain_putamen_basal |
| rs10901448 | 10 | 127507647 | UROS | ENSG00000188690.8 | 5.749E-20 | 0 | 4170 | gtex_brain_putamen_basal |
| rs11599714 | 10 | 127508725 | UROS | ENSG00000188690.8 | 4.261E-17 | 0 | 3092 | gtex_brain_putamen_basal |
| rs10901450 | 10 | 127509294 | UROS | ENSG00000188690.8 | 1.567E-20 | 0 | 2523 | gtex_brain_putamen_basal |
| rs4256900 | 10 | 127511756 | UROS | ENSG00000188690.8 | 1.581E-20 | 0 | 61 | gtex_brain_putamen_basal |
| rs4385801 | 10 | 127511790 | UROS | ENSG00000188690.8 | 1.581E-20 | 0 | 27 | gtex_brain_putamen_basal |
| rs10159992 | 10 | 127515069 | UROS | ENSG00000188690.8 | 4.675E-20 | 0 | -3252 | gtex_brain_putamen_basal |
| rs11244667 | 10 | 127518538 | UROS | ENSG00000188690.8 | 4.446E-18 | 0 | -6721 | gtex_brain_putamen_basal |
| rs2366040 | 10 | 127520429 | UROS | ENSG00000188690.8 | 8.331E-15 | 0 | -8612 | gtex_brain_putamen_basal |
| rs3740206 | 10 | 127522572 | UROS | ENSG00000188690.8 | 4.185E-18 | 0 | -10755 | gtex_brain_putamen_basal |
| rs2185740 | 10 | 127522988 | UROS | ENSG00000188690.8 | 5.512E-18 | 0 | -11171 | gtex_brain_putamen_basal |
| rs201219913 | 10 | 127524167 | UROS | ENSG00000188690.8 | 6.766E-8 | 0 | -12350 | gtex_brain_putamen_basal |
| rs1891360 | 10 | 127524168 | UROS | ENSG00000188690.8 | 4.072E-11 | 0 | -12351 | gtex_brain_putamen_basal |
| rs4075326 | 10 | 127524612 | UROS | ENSG00000188690.8 | 2.756E-18 | 0 | -12795 | gtex_brain_putamen_basal |
| rs7320 | 10 | 127525072 | UROS | ENSG00000188690.8 | 4.378E-15 | 0 | -13255 | gtex_brain_putamen_basal |
| rs3781058 | 10 | 127528267 | UROS | ENSG00000188690.8 | 1.944E-14 | 0 | -16450 | gtex_brain_putamen_basal |
| rs3208565 | 10 | 127530325 | UROS | ENSG00000188690.8 | 1.983E-17 | 0 | -18508 | gtex_brain_putamen_basal |
| rs12049644 | 10 | 127531514 | UROS | ENSG00000188690.8 | 5.028E-15 | 0 | -19697 | gtex_brain_putamen_basal |
| rs11244668 | 10 | 127531959 | UROS | ENSG00000188690.8 | 2.725E-12 | 0 | -20142 | gtex_brain_putamen_basal |
| rs11244669 | 10 | 127532782 | UROS | ENSG00000188690.8 | 5.017E-8 | 0 | -20965 | gtex_brain_putamen_basal |
| rs12356233 | 10 | 127534930 | UROS | ENSG00000188690.8 | 5.028E-15 | 0 | -23113 | gtex_brain_putamen_basal |
| rs10901454 | 10 | 127536267 | UROS | ENSG00000188690.8 | 1.949E-17 | 0 | -24450 | gtex_brain_putamen_basal |
| rs10794027 | 10 | 127536562 | UROS | ENSG00000188690.8 | 5.028E-15 | 0 | -24745 | gtex_brain_putamen_basal |
| rs11244671 | 10 | 127538973 | UROS | ENSG00000188690.8 | 5.028E-15 | 0 | -27156 | gtex_brain_putamen_basal |
| rs10901455 | 10 | 127539196 | UROS | ENSG00000188690.8 | 7.914E-17 | 0 | -27379 | gtex_brain_putamen_basal |
| rs10901456 | 10 | 127545418 | UROS | ENSG00000188690.8 | 1.176E-19 | 0 | -33601 | gtex_brain_putamen_basal |
| rs10794028 | 10 | 127550491 | UROS | ENSG00000188690.8 | 4.91E-15 | 0 | -38674 | gtex_brain_putamen_basal |
| rs11244677 | 10 | 127553359 | UROS | ENSG00000188690.8 | 2.044E-17 | 0 | -41542 | gtex_brain_putamen_basal |
| rs11244678 | 10 | 127554534 | UROS | ENSG00000188690.8 | 4.466E-14 | 0 | -42717 | gtex_brain_putamen_basal |
| rs10794030 | 10 | 127562375 | UROS | ENSG00000188690.8 | 1.488E-19 | 0 | -50558 | gtex_brain_putamen_basal |
| rs10901457 | 10 | 127563509 | UROS | ENSG00000188690.8 | 2.725E-12 | 0 | -51692 | gtex_brain_putamen_basal |
| rs2366050 | 10 | 127564306 | UROS | ENSG00000188690.8 | 3.925E-15 | 0 | -52489 | gtex_brain_putamen_basal |
| rs10794031 | 10 | 127565320 | UROS | ENSG00000188690.8 | 4.98E-19 | 0 | -53503 | gtex_brain_putamen_basal |
| rs11244686 | 10 | 127568260 | UROS | ENSG00000188690.8 | 7.493E-15 | 0 | -56443 | gtex_brain_putamen_basal |
| rs2366053 | 10 | 127571426 | UROS | ENSG00000188690.8 | 5.692E-19 | 0 | -59609 | gtex_brain_putamen_basal |
| rs10901458 | 10 | 127572773 | UROS | ENSG00000188690.8 | 8.307E-15 | 0 | -60956 | gtex_brain_putamen_basal |
| rs10751535 | 10 | 127589202 | UROS | ENSG00000188690.8 | 8.348E-13 | 0 | -77385 | gtex_brain_putamen_basal |
| rs10794036 | 10 | 127590349 | UROS | ENSG00000188690.8 | 8.104E-14 | 0 | -78532 | gtex_brain_putamen_basal |
| rs61871956 | 10 | 127590661 | UROS | ENSG00000188690.8 | 2.007E-15 | 0 | -78844 | gtex_brain_putamen_basal |
| rs7474918 | 10 | 127592385 | UROS | ENSG00000188690.8 | 1.16E-10 | 0 | -80568 | gtex_brain_putamen_basal |
| rs10794037 | 10 | 127596105 | UROS | ENSG00000188690.8 | 3.022E-13 | 0 | -84288 | gtex_brain_putamen_basal |
| rs10901465 | 10 | 127596596 | UROS | ENSG00000188690.8 | 3.058E-13 | 0 | -84779 | gtex_brain_putamen_basal |
| rs4615938 | 10 | 127598226 | UROS | ENSG00000188690.8 | 3.82E-14 | 0 | -86409 | gtex_brain_putamen_basal |
| rs10794038 | 10 | 127600013 | UROS | ENSG00000188690.8 | 4.123E-14 | 0 | -88196 | gtex_brain_putamen_basal |
| rs10901466 | 10 | 127601214 | UROS | ENSG00000188690.8 | 6.368E-12 | 0 | -89397 | gtex_brain_putamen_basal |
| rs12256020 | 10 | 127603156 | UROS | ENSG00000188690.8 | 1.671E-13 | 0 | -91339 | gtex_brain_putamen_basal |
| rs10794039 | 10 | 127606560 | UROS | ENSG00000188690.8 | 2.905E-12 | 0 | -94743 | gtex_brain_putamen_basal |
| rs10901468 | 10 | 127607262 | UROS | ENSG00000188690.8 | 1.039E-11 | 0 | -95445 | gtex_brain_putamen_basal |
| rs11244701 | 10 | 127607827 | UROS | ENSG00000188690.8 | 7.324E-16 | 0 | -96010 | gtex_brain_putamen_basal |
| rs10794040 | 10 | 127614273 | UROS | ENSG00000188690.8 | 4.459E-13 | 0 | -102456 | gtex_brain_putamen_basal |
| rs10901470 | 10 | 127615817 | UROS | ENSG00000188690.8 | 8.575E-13 | 0 | -104000 | gtex_brain_putamen_basal |
| rs11244703 | 10 | 127616324 | UROS | ENSG00000188690.8 | 1.563E-8 | 0 | -104507 | gtex_brain_putamen_basal |
| rs11244704 | 10 | 127616826 | UROS | ENSG00000188690.8 | 5.538E-16 | 0 | -105009 | gtex_brain_putamen_basal |
| rs10901471 | 10 | 127617020 | UROS | ENSG00000188690.8 | 9.327E-16 | 0 | -105203 | gtex_brain_putamen_basal |
| rs144488289 | 10 | 127617030 | UROS | ENSG00000188690.8 | 1.603E-15 | 0 | -105213 | gtex_brain_putamen_basal |
| rs12359733 | 10 | 127620582 | UROS | ENSG00000188690.8 | 2.652E-15 | 0 | -108765 | gtex_brain_putamen_basal |
| rs1949313 | 10 | 127621532 | UROS | ENSG00000188690.8 | 2.652E-15 | 0 | -109715 | gtex_brain_putamen_basal |
| rs11244713 | 10 | 127633638 | UROS | ENSG00000188690.8 | 6.064E-13 | 0 | -121821 | gtex_brain_putamen_basal |
| rs10901473 | 10 | 127634125 | UROS | ENSG00000188690.8 | 2.525E-11 | 0 | -122308 | gtex_brain_putamen_basal |
| rs11244714 | 10 | 127639907 | UROS | ENSG00000188690.8 | 4.604E-16 | 0 | -128090 | gtex_brain_putamen_basal |
| rs10794042 | 10 | 127641756 | UROS | ENSG00000188690.8 | 1.48E-13 | 0 | -129939 | gtex_brain_putamen_basal |
| rs10901475 | 10 | 127642064 | UROS | ENSG00000188690.8 | 1.436E-13 | 0 | -130247 | gtex_brain_putamen_basal |
| rs4403725 | 10 | 127642276 | UROS | ENSG00000188690.8 | 1.403E-13 | 0 | -130459 | gtex_brain_putamen_basal |
| rs10901476 | 10 | 127642617 | UROS | ENSG00000188690.8 | 2.671E-15 | 0 | -130800 | gtex_brain_putamen_basal |
| rs11244716 | 10 | 127642986 | UROS | ENSG00000188690.8 | 2.677E-15 | 0 | -131169 | gtex_brain_putamen_basal |
| rs11244717 | 10 | 127643296 | UROS | ENSG00000188690.8 | 1.245E-13 | 0 | -131479 | gtex_brain_putamen_basal |
| rs11244719 | 10 | 127643599 | UROS | ENSG00000188690.8 | 8.687E-13 | 0 | -131782 | gtex_brain_putamen_basal |
| rs61870940 | 10 | 127643900 | UROS | ENSG00000188690.8 | 2.663E-15 | 0 | -132083 | gtex_brain_putamen_basal |
| rs11244720 | 10 | 127644783 | UROS | ENSG00000188690.8 | 1.797E-15 | 0 | -132966 | gtex_brain_putamen_basal |
| rs10901477 | 10 | 127644935 | UROS | ENSG00000188690.8 | 2.674E-15 | 0 | -133118 | gtex_brain_putamen_basal |
| rs11244722 | 10 | 127646360 | UROS | ENSG00000188690.8 | 2.705E-15 | 0 | -134543 | gtex_brain_putamen_basal |
| rs11244724 | 10 | 127646444 | UROS | ENSG00000188690.8 | 2.716E-15 | 0 | -134627 | gtex_brain_putamen_basal |
| rs11244725 | 10 | 127647134 | UROS | ENSG00000188690.8 | 2.709E-15 | 0 | -135317 | gtex_brain_putamen_basal |
| rs10901481 | 10 | 127647705 | UROS | ENSG00000188690.8 | 2.953E-15 | 0 | -135888 | gtex_brain_putamen_basal |
| rs10901482 | 10 | 127647737 | UROS | ENSG00000188690.8 | 2.715E-15 | 0 | -135920 | gtex_brain_putamen_basal |
| rs398114890 | 10 | 127647810 | UROS | ENSG00000188690.8 | 2.32E-15 | 0 | -135993 | gtex_brain_putamen_basal |
| rs10901483 | 10 | 127649011 | UROS | ENSG00000188690.8 | 2.705E-15 | 0 | -137194 | gtex_brain_putamen_basal |
| rs11244727 | 10 | 127649149 | UROS | ENSG00000188690.8 | 2.708E-15 | 0 | -137332 | gtex_brain_putamen_basal |
| rs11244728 | 10 | 127649188 | UROS | ENSG00000188690.8 | 2.864E-15 | 0 | -137371 | gtex_brain_putamen_basal |
| rs11244729 | 10 | 127649193 | UROS | ENSG00000188690.8 | 1.193E-14 | 0 | -137376 | gtex_brain_putamen_basal |
| rs11244733 | 10 | 127651741 | UROS | ENSG00000188690.8 | 6.067E-15 | 0 | -139924 | gtex_brain_putamen_basal |
| rs10458780 | 10 | 127652028 | UROS | ENSG00000188690.8 | 6.707E-8 | 0 | -140211 | gtex_brain_putamen_basal |
| rs76339414 | 10 | 127652326 | UROS | ENSG00000188690.8 | 5.553E-15 | 0 | -140509 | gtex_brain_putamen_basal |
| rs7358157 | 10 | 127653081 | UROS | ENSG00000188690.8 | 5.558E-15 | 0 | -141264 | gtex_brain_putamen_basal |
| rs10458781 | 10 | 127653583 | UROS | ENSG00000188690.8 | 3.72E-12 | 0 | -141766 | gtex_brain_putamen_basal |
| rs10794045 | 10 | 127653940 | UROS | ENSG00000188690.8 | 5.544E-15 | 0 | -142123 | gtex_brain_putamen_basal |
| rs10794046 | 10 | 127654536 | UROS | ENSG00000188690.8 | 1.251E-13 | 0 | -142719 | gtex_brain_putamen_basal |
| rs10901484 | 10 | 127654672 | UROS | ENSG00000188690.8 | 5.591E-15 | 0 | -142855 | gtex_brain_putamen_basal |
| rs10901486 | 10 | 127655852 | UROS | ENSG00000188690.8 | 5.312E-15 | 0 | -144035 | gtex_brain_putamen_basal |
| rs10901487 | 10 | 127655861 | UROS | ENSG00000188690.8 | 5.306E-15 | 0 | -144044 | gtex_brain_putamen_basal |
| rs11244734 | 10 | 127656114 | UROS | ENSG00000188690.8 | 5.296E-15 | 0 | -144297 | gtex_brain_putamen_basal |
| rs10901488 | 10 | 127657666 | UROS | ENSG00000188690.8 | 7.546E-15 | 0 | -145849 | gtex_brain_putamen_basal |
| rs11244736 | 10 | 127658731 | UROS | ENSG00000188690.8 | 1.818E-13 | 0 | -146914 | gtex_brain_putamen_basal |
| rs11244737 | 10 | 127658748 | UROS | ENSG00000188690.8 | 2.91E-13 | 0 | -146931 | gtex_brain_putamen_basal |
| rs61870942 | 10 | 127659131 | UROS | ENSG00000188690.8 | 6.825E-14 | 0 | -147314 | gtex_brain_putamen_basal |
| rs11244738 | 10 | 127660351 | UROS | ENSG00000188690.8 | 1.023E-6 | 0 | -148534 | gtex_brain_putamen_basal |
| rs10901491 | 10 | 127660777 | UROS | ENSG00000188690.8 | 1.895E-7 | 0 | -148960 | gtex_brain_putamen_basal |
| rs3812685 | 10 | 127661022 | UROS | ENSG00000188690.8 | 1.822E-9 | 0 | -149205 | gtex_brain_putamen_basal |
| rs151081626 | 10 | 127661373 | UROS | ENSG00000188690.8 | 3.667E-9 | 0 | -149556 | gtex_brain_putamen_basal |
| rs11244740 | 10 | 127662829 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -151012 | gtex_brain_putamen_basal |
| rs11244741 | 10 | 127662975 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -151158 | gtex_brain_putamen_basal |
| rs12356665 | 10 | 127663380 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -151563 | gtex_brain_putamen_basal |
| rs7078337 | 10 | 127663957 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -152140 | gtex_brain_putamen_basal |
| rs11528564 | 10 | 127665932 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -154115 | gtex_brain_putamen_basal |
| rs11244742 | 10 | 127666587 | UROS | ENSG00000188690.8 | 2.514E-10 | 0 | -154770 | gtex_brain_putamen_basal |
| rs397797720 | 10 | 127666887 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -155070 | gtex_brain_putamen_basal |
| rs35717616 | 10 | 127667376 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -155559 | gtex_brain_putamen_basal |
| rs35713731 | 10 | 127667412 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -155595 | gtex_brain_putamen_basal |
| rs34203433 | 10 | 127667543 | UROS | ENSG00000188690.8 | 1.913E-8 | 0 | -155726 | gtex_brain_putamen_basal |
| rs35958975 | 10 | 127667708 | UROS | ENSG00000188690.8 | 2.257E-8 | 0 | -155891 | gtex_brain_putamen_basal |
| rs34120875 | 10 | 127667812 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -155995 | gtex_brain_putamen_basal |
| rs35451781 | 10 | 127667881 | UROS | ENSG00000188690.8 | 5.24E-8 | 0 | -156064 | gtex_brain_putamen_basal |
| rs56266020 | 10 | 127668033 | UROS | ENSG00000188690.8 | 2.242E-8 | 0 | -156216 | gtex_brain_putamen_basal |
| rs56040808 | 10 | 127668048 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -156231 | gtex_brain_putamen_basal |
| rs56132121 | 10 | 127668056 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -156239 | gtex_brain_putamen_basal |
| rs11244744 | 10 | 127668317 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -156500 | gtex_brain_putamen_basal |
| rs11244745 | 10 | 127668431 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -156614 | gtex_brain_putamen_basal |
| rs2176097 | 10 | 127668487 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -156670 | gtex_brain_putamen_basal |
| rs2138275 | 10 | 127668610 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -156793 | gtex_brain_putamen_basal |
| rs2366341 | 10 | 127669318 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -157501 | gtex_brain_putamen_basal |
| rs11818112 | 10 | 127669384 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -157567 | gtex_brain_putamen_basal |
| rs11814311 | 10 | 127669555 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -157738 | gtex_brain_putamen_basal |
| rs398054833 | 10 | 127669588 | UROS | ENSG00000188690.8 | 3.728E-8 | 0 | -157771 | gtex_brain_putamen_basal |
| rs10901492 | 10 | 127669761 | UROS | ENSG00000188690.8 | 2.137E-8 | 0 | -157944 | gtex_brain_putamen_basal |
| rs10901493 | 10 | 127670411 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -158594 | gtex_brain_putamen_basal |
| rs11244748 | 10 | 127670426 | UROS | ENSG00000188690.8 | 2.184E-8 | 0 | -158609 | gtex_brain_putamen_basal |
| rs1913740 | 10 | 127670780 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -158963 | gtex_brain_putamen_basal |
| rs10794047 | 10 | 127671038 | UROS | ENSG00000188690.8 | 1.555E-8 | 0 | -159221 | gtex_brain_putamen_basal |
| rs10901494 | 10 | 127671071 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -159254 | gtex_brain_putamen_basal |
| rs10794048 | 10 | 127671152 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -159335 | gtex_brain_putamen_basal |
| rs10901495 | 10 | 127671203 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -159386 | gtex_brain_putamen_basal |
| rs10794049 | 10 | 127671377 | UROS | ENSG00000188690.8 | 4.217E-7 | 0 | -159560 | gtex_brain_putamen_basal |
| rs2366342 | 10 | 127671466 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -159649 | gtex_brain_putamen_basal |
| rs2366343 | 10 | 127671666 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -159849 | gtex_brain_putamen_basal |
| rs2366344 | 10 | 127671692 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -159875 | gtex_brain_putamen_basal |
| rs2366345 | 10 | 127671790 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -159973 | gtex_brain_putamen_basal |
| rs2138276 | 10 | 127671865 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -160048 | gtex_brain_putamen_basal |
| rs2138277 | 10 | 127672039 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -160222 | gtex_brain_putamen_basal |
| rs2090248 | 10 | 127672759 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -160942 | gtex_brain_putamen_basal |
| rs10901496 | 10 | 127673483 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -161666 | gtex_brain_putamen_basal |
| rs71486562 | 10 | 127673668 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -161851 | gtex_brain_putamen_basal |
| rs11244750 | 10 | 127673877 | UROS | ENSG00000188690.8 | 4.424E-7 | 0 | -162060 | gtex_brain_putamen_basal |
| rs11244751 | 10 | 127674027 | UROS | ENSG00000188690.8 | 8.626E-10 | 0 | -162210 | gtex_brain_putamen_basal |
| rs9633754 | 10 | 127674353 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -162536 | gtex_brain_putamen_basal |
| rs2366347 | 10 | 127674508 | UROS | ENSG00000188690.8 | 4.217E-7 | 0 | -162691 | gtex_brain_putamen_basal |
| rs2366349 | 10 | 127674675 | UROS | ENSG00000188690.8 | 4.217E-7 | 0 | -162858 | gtex_brain_putamen_basal |
| rs11244752 | 10 | 127675130 | UROS | ENSG00000188690.8 | 4.217E-7 | 0 | -163313 | gtex_brain_putamen_basal |
| rs3812683 | 10 | 127675607 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -163790 | gtex_brain_putamen_basal |
| rs4420176 | 10 | 127676198 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -164381 | gtex_brain_putamen_basal |
| rs2280173 | 10 | 127677374 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -165557 | gtex_brain_putamen_basal |
| rs7085584 | 10 | 127677570 | UROS | ENSG00000188690.8 | 2.232E-8 | 0 | -165753 | gtex_brain_putamen_basal |
| rs2277217 | 10 | 127677676 | UROS | ENSG00000188690.8 | 2.284E-10 | 0 | -165859 | gtex_brain_putamen_basal |
| rs7900129 | 10 | 127679403 | UROS | ENSG00000188690.8 | 1.435E-7 | 0 | -167586 | gtex_brain_putamen_basal |
| rs10901501 | 10 | 127683640 | UROS | ENSG00000188690.8 | 2.016E-9 | 0 | -171823 | gtex_brain_putamen_basal |
| rs10901502 | 10 | 127683743 | UROS | ENSG00000188690.8 | 2.016E-9 | 0 | -171926 | gtex_brain_putamen_basal |
| rs10901503 | 10 | 127685323 | UROS | ENSG00000188690.8 | 2.016E-9 | 0 | -173506 | gtex_brain_putamen_basal |
| rs10901504 | 10 | 127685570 | UROS | ENSG00000188690.8 | 2.016E-9 | 0 | -173753 | gtex_brain_putamen_basal |
| rs11244755 | 10 | 127687017 | UROS | ENSG00000188690.8 | 4.558E-7 | 0 | -175200 | gtex_brain_putamen_basal |
| rs397847521 | 10 | 127687312 | UROS | ENSG00000188690.8 | 2.016E-9 | 0 | -175495 | gtex_brain_putamen_basal |
| rs71486566 | 10 | 127689542 | UROS | ENSG00000188690.8 | 1.76E-7 | 0 | -177725 | gtex_brain_putamen_basal |
| rs199702515 | 10 | 127689546 | UROS | ENSG00000188690.8 | 1.77E-7 | 0 | -177729 | gtex_brain_putamen_basal |
| rs2090249 | 10 | 127692391 | UROS | ENSG00000188690.8 | 1.692E-9 | 0 | -180574 | gtex_brain_putamen_basal |
| rs10901513 | 10 | 127699936 | UROS | ENSG00000188690.8 | 5.801E-10 | 0 | -188119 | gtex_brain_putamen_basal |
| rs10901514 | 10 | 127700066 | UROS | ENSG00000188690.8 | 5.801E-10 | 0 | -188249 | gtex_brain_putamen_basal |
| rs7082311 | 10 | 127700408 | UROS | ENSG00000188690.8 | 5.801E-10 | 0 | -188591 | gtex_brain_putamen_basal |
| rs3781001 | 10 | 127706028 | UROS | ENSG00000188690.8 | 5.801E-10 | 0 | -194211 | gtex_brain_putamen_basal |
| rs34845021 | 10 | 127707961 | UROS | ENSG00000188690.8 | 1.167E-9 | 0 | -196144 | gtex_brain_putamen_basal |
| rs35835884 | 10 | 127708468 | UROS | ENSG00000188690.8 | 1.821E-9 | 0 | -196651 | gtex_brain_putamen_basal |
| rs11244772 | 10 | 127711296 | UROS | ENSG00000188690.8 | 1.358E-6 | 0 | -199479 | gtex_brain_putamen_basal |
| rs10901520 | 10 | 127718837 | UROS | ENSG00000188690.8 | 5.801E-10 | 0 | -207020 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MICAL2 | 0.94 | 0.78 |
| EXTL1 | 0.93 | 0.87 |
| MFSD4 | 0.93 | 0.82 |
| KCNIP3 | 0.93 | 0.90 |
| TYRO3 | 0.92 | 0.75 |
| TMEM38A | 0.92 | 0.88 |
| KCNK1 | 0.91 | 0.87 |
| PACSIN1 | 0.91 | 0.88 |
| TOLLIP | 0.91 | 0.74 |
| CAMK2A | 0.91 | 0.88 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FADS2 | -0.55 | -0.61 |
| BCL7C | -0.55 | -0.72 |
| TUBB2B | -0.53 | -0.69 |
| PDE9A | -0.53 | -0.69 |
| KIAA1949 | -0.53 | -0.62 |
| TRAF4 | -0.53 | -0.70 |
| PKN1 | -0.52 | -0.64 |
| SH3BP2 | -0.52 | -0.67 |
| HEBP2 | -0.52 | -0.80 |
| GPR125 | -0.52 | -0.51 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0004852 | uroporphyrinogen-III synthase activity | IEA | - | |
| GO:0016829 | lyase activity | IEA | - | |
| GO:0016491 | oxidoreductase activity | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0008152 | metabolic process | IEA | - | |
| GO:0006783 | heme biosynthetic process | IEA | - | |
| GO:0006780 | uroporphyrinogen III biosynthetic process | TAS | 2331520 | |
| GO:0006779 | porphyrin biosynthetic process | IEA | - | |
| GO:0033014 | tetrapyrrole biosynthetic process | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005739 | mitochondrion | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG PORPHYRIN AND CHLOROPHYLL METABOLISM | 41 | 23 | All SZGR 2.0 genes in this pathway |
| BIOCARTA AHSP PATHWAY | 13 | 6 | All SZGR 2.0 genes in this pathway |
| REACTOME METABOLISM OF PORPHYRINS | 14 | 7 | All SZGR 2.0 genes in this pathway |
| HOLLMANN APOPTOSIS VIA CD40 DN | 267 | 178 | All SZGR 2.0 genes in this pathway |
| LIU SOX4 TARGETS DN | 309 | 191 | All SZGR 2.0 genes in this pathway |
| CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN | 663 | 425 | All SZGR 2.0 genes in this pathway |
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | 1382 | 904 | All SZGR 2.0 genes in this pathway |
| BORCZUK MALIGNANT MESOTHELIOMA UP | 305 | 185 | All SZGR 2.0 genes in this pathway |
| ROVERSI GLIOMA COPY NUMBER DN | 54 | 37 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 UP | 309 | 199 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | 637 | 377 | All SZGR 2.0 genes in this pathway |
| WELCH GATA1 TARGETS | 22 | 12 | All SZGR 2.0 genes in this pathway |
| BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS | 882 | 572 | All SZGR 2.0 genes in this pathway |
| PENG RAPAMYCIN RESPONSE UP | 203 | 130 | All SZGR 2.0 genes in this pathway |
| LU AGING BRAIN DN | 153 | 120 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE DN | 1237 | 837 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 24HR DN | 148 | 102 | All SZGR 2.0 genes in this pathway |
| WANG CISPLATIN RESPONSE AND XPC DN | 228 | 146 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 18HR DN | 178 | 121 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT DN | 165 | 106 | All SZGR 2.0 genes in this pathway |
| DOUGLAS BMI1 TARGETS DN | 314 | 188 | All SZGR 2.0 genes in this pathway |
| MONNIER POSTRADIATION TUMOR ESCAPE DN | 373 | 196 | All SZGR 2.0 genes in this pathway |
| MOOTHA HUMAN MITODB 6 2002 | 429 | 260 | All SZGR 2.0 genes in this pathway |
| KYNG RESPONSE TO H2O2 VIA ERCC6 UP | 40 | 30 | All SZGR 2.0 genes in this pathway |
| KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP | 756 | 494 | All SZGR 2.0 genes in this pathway |
| KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP | 682 | 440 | All SZGR 2.0 genes in this pathway |
| VERHAAK GLIOBLASTOMA NEURAL | 129 | 85 | All SZGR 2.0 genes in this pathway |
| LIM MAMMARY STEM CELL DN | 428 | 246 | All SZGR 2.0 genes in this pathway |